The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Electrooculography


Psychiatry related information on Electrooculography


High impact information on Electrooculography

  • Interestingly, electroolfactogram (EOG) responses stimulated by either cAMP- or inositol 1,4,5-triphosphate- (IP3-) inducing odorants were completely ablated in AC3 mutants, despite the presence of AC2 and AC4 in olfactory cilia [8].
  • The basolateral plasma membrane localization of bestrophin suggests the possibility that bestrophin plays a role in generating the altered electrooculogram of individuals with Best disease [9].
  • It is encoded by the VMD2 gene, which is mutated in Best macular dystrophy, a disease characterized by a depressed light peak in the electrooculogram [10].
  • BMD is distinguished from AVMD by a diminished electrooculogram light peak (LP) in the absence of changes in the flash electroretinogram [11].
  • EOG, a more sensitive diagnostic tool than ERG for screening vigabatrin-treated patients, also appears to be more specific [12].

Biological context of Electrooculography

  • We examined the relationship between eye movement direction in REM sleep recorded by electrooculograph (EOG) and gaze direction in dream imagery [13].
  • Electroencephalogram (EEG) and electrooculogram (EOG) were recorded while subjects performed the tasks and LORETA source analysis was performed on event-related potential (ERP) components [14].
  • Serial electrophysiological brainstem tests including masseter reflex, blink reflex, masseter inhibitory reflex, AEP, MEP, EOG and the oculoauricular phenomenon were applied [15].
  • Periodic examinations by ophthalmoscopy and by functional tests such as EOG and visual fields should be continued in patients at risk of delayed-onset chloroquine retinopathy after discontinuance of the drug [16].
  • Mental and musical abilities of both groups were controlled by standardized tests (Kaufman's ABC and Gordon's PMMA) and compared with data taken from recordings of saccadic eye movement using online identification from an electrooculogram (EOG) [17].

Anatomical context of Electrooculography


Associations of Electrooculography with chemical compounds

  • Electro-olfactogram (EOG) recording also demonstrated that the olfactory system of migratory adult sea lamprey is acutely and specifically sensitive to ACA and PS; detection thresholds for these compounds were approximately 10(-12) M [22].
  • CONCLUSIONS: Alcohol and light act through separate pathways to form a final common pathway inside the RPE cell that is responsible for triggering the timing of the slow oscillatory changes of EOG voltage [23].
  • Twelve-hour recordings of electrocardiogram, electroencephalogram, digastric electromyogram, electrooculogram and expired CO2 were obtained from 25 normal infants at 1 week and 1, 2, 3, 4 and 6 months of age [24].
  • Octanal and other aldehydes induce large EOG responses in the rodent olfactory epithelium, suggesting that these compounds activate a large number of odour receptors (ORs) [25].
  • The effects of fluoxetine on automated measures of electrooculographic (EOG) and electromyographic (EMG) activity were evaluated in 41 patients with nonpsychotic, major depressive disorder [26].

Gene context of Electrooculography

  • Four individuals who did not have maculopathy, but did have an abnormal EOG, also had mutations in the VMD2 gene [27].
  • Evidence is presented to suggest that the FO component of the EOG is mediated directly or indirectly by CFTR [28].
  • Analyses of the patterns of EOG responses to the test stimuli identified and characterized the respective "transduction processes," a term used to describe membrane events initiated by a particular subset of amino acid stimuli that are intricately linked to the origin of the olfactory receptor potential [29].
  • Electro-oculographic recordings (EOG) were made on 26 patients with Machado-Joseph disease or at genetic risk for that disease [30].
  • The dream narratives and EOG activity occurring prior to the REM awakenings were each reduced to a series of quantitatively scaled ratings [13].

Analytical, diagnostic and therapeutic context of Electrooculography

  • This study evaluated the effects of flurazepam 30 mg, lorazepam 4 mg, triazolam 0.5 mg, and placebo upon sleep and memory in eleven normal male subjects continuously monitored for nighttime EEG, EOG, and EMG recording [31].
  • METHODS: Sixty-four consecutive patients with a history of partial seizures currently treated with VGB with either carbamazepine (CBZ) or valproate (VPA) were examined with automated kinetic perimetry, static perimetry, electrooculogram (EOG), and electroretinogram (ERG) [32].
  • The ophthalmological examination included ophthalmoscopy, fluorescein angiography, electroretinogram and electrooculogram [33].
  • The magnitude of this subtraction-phase error is compared to between-subject ERP variability and to error associated with EOG rejection (omitting data contaminated by ocular artefact) [34].
  • We recorded the alcohol-induced EOG response after a single oral administration of ethanol at 160 mg/kg, followed by an ISCEV-standard EOG [35].


  1. Effects of chronic lithium treatment on retinal electrophysiologic function. Lam, R.W., Allain, S., Sullivan, K., Beattie, C.W., Remick, R.A., Zis, A.P. Biol. Psychiatry (1997) [Pubmed]
  2. Slow saccades and other eye movement disorders in spinocerebellar atrophy type 1. Klostermann, W., Zühlke, C., Heide, W., Kömpf, D., Wessel, K. J. Neurol. (1997) [Pubmed]
  3. EOG as a monitor of desferrioxamine retinal toxicity. Hidajat, R.R., McLay, J.L., Goode, D.H., Spearing, R.L. Documenta ophthalmologica. Advances in ophthalmology. (2004) [Pubmed]
  4. Studies on the psychosomatic functioning of ill-health according to Eastern and Western medicine 5. Psychosomatic characteristics of anxiety and anxiety-affinitive constitution. Takeichi, M., Sato, T., Takefu, M., Shigematsu, M., Shimohira, H., Katsuki, T. Am. J. Chin. Med. (2001) [Pubmed]
  5. Dominantly inherited cystoid macular edema. Fishman, G.A., Goldberg, M.F., Trautmann, J.C. Annals of ophthalmology. (1979) [Pubmed]
  6. Horizontal component of electro-oculogram as a parameter of arousal in dementia: relationship between intellectual improvement and increasing arousal under pharmacotherapy. Shigeta, M., Nishikawa, Y., Shimizu, M., Usui, M., Hyoki, K., Kawamuro, Y. Journal of clinical pharmacology. (1993) [Pubmed]
  7. The diagnostic value of eye movement recordings in patients with Huntington's disease and their offspring. Beenen, N., Büttner, U., Lange, H.W. Electroencephalography and clinical neurophysiology. (1986) [Pubmed]
  8. Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice. Wong, S.T., Trinh, K., Hacker, B., Chan, G.C., Lowe, G., Gaggar, A., Xia, Z., Gold, G.H., Storm, D.R. Neuron (2000) [Pubmed]
  9. Bestrophin, the product of the Best vitelliform macular dystrophy gene (VMD2), localizes to the basolateral plasma membrane of the retinal pigment epithelium. Marmorstein, A.D., Marmorstein, L.Y., Rayborn, M., Wang, X., Hollyfield, J.G., Petrukhin, K. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  10. Bestrophin interacts physically and functionally with protein phosphatase 2A. Marmorstein, L.Y., McLaughlin, P.J., Stanton, J.B., Yan, L., Crabb, J.W., Marmorstein, A.D. J. Biol. Chem. (2002) [Pubmed]
  11. The Light Peak of the Electroretinogram Is Dependent on Voltage-gated Calcium Channels and Antagonized by Bestrophin (Best-1). Marmorstein, L.Y., Wu, J., McLaughlin, P., Yocom, J., Karl, M.O., Neussert, R., Wimmers, S., Stanton, J.B., Gregg, R.G., Strauss, O., Peachey, N.S., Marmorstein, A.D. J. Gen. Physiol. (2006) [Pubmed]
  12. Outer retinal dysfunction in patients treated with vigabatrin. Arndt, C.F., Derambure, P., Defoort-Dhellemmes, S., Hache, J.C. Neurology (1999) [Pubmed]
  13. Evidence for a directional correspondence between eye movements and dream imagery in REM sleep. Herman, J.H., Erman, M., Boys, R., Peiser, L., Taylor, M.E., Roffwarg, H.P. Sleep. (1984) [Pubmed]
  14. Time course of cross-hemispheric spatial updating in the human parietal cortex. Bellebaum, C., Daum, I. Behav. Brain Res. (2006) [Pubmed]
  15. Electrophysiological brainstem testing in the diagnosis of reversible brainstem ischemia. Marx, J.J., Mika-Gruettner, A., Thoemke, F., Fitzek, S., Fitzek, C., Vucurevic, G., Urban, P.P., Stoeter, P., Hopf, H.C. J. Neurol. (2002) [Pubmed]
  16. Delayed-onset chloroquine retinopathy. Ehrenfeld, M., Nesher, R., Merin, S. The British journal of ophthalmology. (1986) [Pubmed]
  17. Do mental speed and musical abilities interact? Gruhn, W., Galley, N., Kluth, C. Ann. N. Y. Acad. Sci. (2003) [Pubmed]
  18. Saccadic eye movements in myasthenia gravis. Yee, R.D., Whitcup, S.M., Williams, I.M., Baloh, R.W., Honrubia, V. Ophthalmology (1987) [Pubmed]
  19. The fast oscillation of the electrooculogram reveals sensitivity of the human outer retina/retinal pigment epithelium to glucose level. Schneck, M.E., Fortune, B., Adams, A.J. Vision Res. (2000) [Pubmed]
  20. Differential effects of mercurial compounds on the electroolfactogram (EOG) of salmon (Salmo salar L.). Baatrup, E., Døving, K.B., Winberg, S. Ecotoxicol. Environ. Saf. (1990) [Pubmed]
  21. Degenerative choroidal sclerosis with a peculiar bilateral pattern. Zimmerman, T.J., Fitzgerald, C.R. Annals of ophthalmology. (1975) [Pubmed]
  22. The olfactory system of migratory adult sea lamprey (Petromyzon marinus) is specifically and acutely sensitive to unique bile acids released by conspecific larvae. Li, W., Sorensen, P.W., Gallaher, D.D. J. Gen. Physiol. (1995) [Pubmed]
  23. The human electro-oculogram: interaction of light and alcohol. Arden, G.B., Wolf, J.E. Invest. Ophthalmol. Vis. Sci. (2000) [Pubmed]
  24. The maturation of correlations between cardiac and respiratory measures across sleep states in normal infants. Schechtman, V.L., Harper, R.M. Sleep. (1992) [Pubmed]
  25. A pharmacological profile of the aldehyde receptor repertoire in rat olfactory epithelium. Araneda, R.C., Peterlin, Z., Zhang, X., Chesler, A., Firestein, S. J. Physiol. (Lond.) (2004) [Pubmed]
  26. Fluoxetine and oculomotor activity during sleep in depressed patients. Armitage, R., Trivedi, M., Rush, A.J. Neuropsychopharmacology (1995) [Pubmed]
  27. Phenotype and genotype correlations in two best families. Seddon, J.M., Sharma, S., Chong, S., Hutchinson, A., Allikmets, R., Adelman, R.A. Ophthalmology (2003) [Pubmed]
  28. Retinal pigment epithelial function: a role for CFTR? Blaug, S., Quinn, R., Quong, J., Jalickee, S., Miller, S.S. Documenta ophthalmologica. Advances in ophthalmology. (2003) [Pubmed]
  29. Electrophysiological evidence for acidic, basic, and neutral amino acid olfactory receptor sites in the catfish. Caprio, J., Byrd, R.P. J. Gen. Physiol. (1984) [Pubmed]
  30. Electro-oculographic findings in Machado-Joseph disease. Dawson, D.M., Feudo, P., Zubick, H.H., Rosenberg, R., Fowler, H. Neurology (1982) [Pubmed]
  31. The effects of flurazepam, lorazepam, and triazolam on sleep and memory. Roth, T., Hartse, K.M., Saab, P.G., Piccione, P.M., Kramer, M. Psychopharmacology (Berl.) (1980) [Pubmed]
  32. The effect on vision of associated treatments in patients taking vigabatrin: carbamazepine versus valproate. Arndt, C.F., Salle, M., Derambure, P.H., Defoort-Dhellemmes, S., Hache, J.C. Epilepsia (2002) [Pubmed]
  33. Charcot-Marie-Tooth disease associated with retinal pigment dystrophy and protanopia. Neurological, ophthalmological and genetic study of a family. Khoubesserian, P., van Regemorter, N., Ohrn-Degueldre, O., Toussaint, D., Telerman-Toppet, N., Coërs, C. J. Neurol. (1979) [Pubmed]
  34. Issues relating to the subtraction phase in EOG artefact correction of the EEG. Croft, R.J., Barry, R.J. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. (2002) [Pubmed]
  35. Alcohol- and Light-induced Electro-oculographic Responses in Age-related Macular Degeneration & Central Serous Chorioretinopathy Alcohol- and Light-induced EOG Responses in ARMD & CSC. Wu, K.H., Marmor, M.F. Documenta ophthalmologica. Advances in ophthalmology. (2005) [Pubmed]
WikiGenes - Universities