Chemical Compound Review:
Omadine 1-hydroxypyridine-2-thione
Synonyms:
Pyrithion, pyrithione, SureCN49266, ACMC-1BNPO, AG-D-31053, ...
- Membrane-permeant chelators can attenuate Zn2+-induced cortical neuronal death. Canzoniero, L.M., Manzerra, P., Sheline, C.T., Choi, D.W. Neuropharmacology (2003)
- Studies on cytotoxic and genotoxic effects of N-hydroxypyridine-2-thione (Omadine) in L5178Y mouse lymphoma cells. Möller, M., Adam, W., Saha-Möller, C.R., Stopper, H. Toxicol. Lett. (2002)
- Growth and survival of Klebsiella pneumoniae in the presence of pyrithione. Khattar, M.M., Salt, W.G., Stretton, R.J. Journal of chemotherapy (Florence, Italy) (1989)
- Antimicrobial susceptibility changes and T-OMP shifts in pyrithione-passaged planktonic cultures of Pseudomonas aeruginosa PAO1. Abdel-Malek, S.M., Al-Adham, I.S., Winder, C.L., Buultjens, T.E., Gartland, K.M., Collier, P.J. J. Appl. Microbiol. (2002)
- The influence of pyrithione on the growth of micro-organisms. Khattar, M.M., Salt, W.G., Stretton, R.J. J. Appl. Bacteriol. (1988)
- Comparison of activity of deferoxamine with that of oral iron chelators against human neuroblastoma cell lines. Blatt, J., Taylor, S.R., Kontoghiorghes, G.J. Cancer Res. (1989)
- Oxidative stress inhibits calpain activity in situ. Guttmann, R.P., Johnson, G.V. J. Biol. Chem. (1998)
- Zinc induces cell death in immortalized embryonic hippocampal cells via activation of Akt-GSK-3beta signaling. Kyu Min, Y., Eun Lee, J., Chul Chung, K. Exp. Cell Res. (2007)
- Role for zinc in a cellular response mediated by protein kinase C in human B lymphocytes. Forbes, I.J., Zalewski, P.D., Giannakis, C. Exp. Cell Res. (1991)
- Zn2+-induced ERK activation mediated by reactive oxygen species causes cell death in differentiated PC12 cells. Seo, S.R., Chong, S.A., Lee, S.I., Sung, J.Y., Ahn, Y.S., Chung, K.C., Seo, J.T. J. Neurochem. (2001)
- The interactive effects of binary mixtures of three antifouling biocides and three heavy metals against the marine algae Chaetoceros gracilis. Koutsaftis, A., Aoyama, I. Environ. Toxicol. (2006)
- Exogenous intracellular, but not extracellular, iron augments myocardial reperfusion injury. Lesnefsky, E.J., Ye, J. Am. J. Physiol. (1994)
- Correlation of apoptosis with change in intracellular labile Zn(II) using zinquin [(2-methyl-8-p-toluenesulphonamido-6-quinolyloxy)acetic acid], a new specific fluorescent probe for Zn(II). Zalewski, P.D., Forbes, I.J., Betts, W.H. Biochem. J. (1993)
- Requirement of caspase and p38MAPK activation in zinc-induced apoptosis in human leukemia HL-60 cells. Kondoh, M., Tasaki, E., Araragi, S., Takiguchi, M., Higashimoto, M., Watanabe, Y., Sato, M. Eur. J. Biochem. (2002)
- Nuclear factor-kappaB inhibitors abolish hypoxic vasoconstriction in sheep-isolated pulmonary arteries. Uzun, O., Demiryürek, A.T. Eur. J. Pharmacol. (2003)
- Zinc ions potentiate adenosine diphosphate-induced platelet aggregation by activation of protein kinase C. Kowalska, M.A., Juliano, D., Trybulec, M., Lu, W., Niewiarowski, S. J. Lab. Clin. Med. (1994)
- Indirect estimation of degradation time for zinc pyrithione and copper pyrithione in seawater. Maraldo, K., Dahllöf, I. Mar. Pollut. Bull. (2004)
- Comparison of leukocytes labeled with indium-111-2-mercaptopyridine-N-oxide and indium-111 oxine for abscess detection. Intenzo, C.M., Desai, A.G., Thakur, M.L., Park, C.H. J. Nucl. Med. (1987)
- Astrocytes are more resistant than neurons to the cytotoxic effects of increased [Zn(2+)](i). Dineley, K.E., Scanlon, J.M., Kress, G.J., Stout, A.K., Reynolds, I.J. Neurobiol. Dis. (2000)
- Mechanism of pyrithione-induced membrane depolarization in Neurospora crassa. Ermolayeva, E., Sanders, D. Appl. Environ. Microbiol. (1995)
- S100A9 deficiency alters adenosine-5'-triphosphate induced calcium signalling but does not generally interfere with calcium and zinc homeostasis in murine neutrophils. Nacken, W., Mooren, F.C., Manitz, M.P., Bode, G., Sorg, C., Kerkhoff, C. Int. J. Biochem. Cell Biol. (2005)
- Zinc induces apoptosis that can be suppressed by lanthanum in C6 rat glioma cells. Haase, H., Wätjen, W., Beyersmann, D. Biol. Chem. (2001)
- In vitro effects of three iron chelators on mitogen-activated lymphocytes: identification of differences in their mechanisms of action. van Reyk, D.M., Sarel, S., Hunt, N.H. Int. J. Immunopharmacol. (1992)
- Indium 111-mercaptopyridine N-oxide-labeled human leukocytes and platelets: mechanism of labeling and intracellular location of 111In and mercaptopyridine N-oxide. Thakur, M.L., McKenney, S.M. J. Lab. Clin. Med. (1986)
- The effect of coal tar distillate, cadmium sulfide, ichthyol sodium and omadine MDS on the epidermis of the guinea pig. Gloor, M., Dressel, M., Schnyder, U.W. Dermatologica (1978)
- Mercaptopyridine-N-oxide, an NADH-fumarate reductase inhibitor, blocks Trypanosoma cruzi growth in culture and in infected myoblasts. Turrens, J.F., Newton, C.L., Zhong, L., Hernandez, F.R., Whitfield, J., Docampo, R. FEMS Microbiol. Lett. (1999)
- Zinc increases phorbol ester receptors in intact B-cells, neutrophil polymorphs and platelets. Forbes, I.J., Zalewski, P.D., Hurst, N.P., Giannakis, C., Whitehouse, M.W. FEBS Lett. (1989)
- High-performance capillary electrophoresis determination of pyrithione in antidandruff preparations and shampoos. Peña-Méndez, E.M., Havel, J., Malecek, J. Journal of capillary electrophoresis. (1997)
- 3-Alkylpyridinium compounds as potential non-toxic antifouling agents. Sepcić, K., Turk, T. Prog. Mol. Subcell. Biol. (2006)