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MeSH Review


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Disease relevance of Curettage


High impact information on Curettage

  • The procedure was performed with the idea that an element of faulty hematopoietic microenvironment existed and that regeneration of normal marrow might occur in areas distant from the site of curettage [6].
  • EXPERIMENTAL DESIGN: Two hundred twenty-six postmenopausal women who had received adjuvant tamoxifen 20 mg/d (> or =12 months, < or =48 months) and developed abnormal vaginal bleeding and/or an asymptomatic endometrial thickness >10 mm [measured by transvaginal ultrasound (TVUS)] were subjected to hysteroscopy and dilation and curettage (D&C) [7].
  • The present study is the first dealing with the demonstration of estrogen receptors (ER) in up to 8-year-old paraffin blocks of endometrial curettage samples routinely fixed in 10% formalin [8].
  • One hundred and thirty-seven consecutive acute superficial abscesses were randomly allocated to incision, curettage and primary suture without parenteral antibiotics (64 cases) or to conventional treatment with incision, drainage and dressings (73 cases) [9].
  • The majority of women whose endometria demonstrated metaplastic transformation were postmenopausal, and most had received some form of oral estrogen replacement therapy within 3 months of the time of curettage or endometrial biopsy [10].

Chemical compound and disease context of Curettage


Biological context of Curettage


Anatomical context of Curettage


Associations of Curettage with chemical compounds


Gene context of Curettage

  • RESULTS: The four groups of complete and incomplete diagnosed hydatiform moles, spontaneous abortions and retention curettage were matched in pairs and evaluated according to the PCNA index [30].
  • Estrogen receptors (ER) and progesterone receptors (PR) were determined on curettages from women with endometrial adenocarcinoma [31].
  • For PR determination on curettage material the DCC assay seems more accurate than EIA [31].
  • The most important single pretreatment factor combined with the presence of residual carcinoma was myometrial fragments with infiltrating carcinoma in the curettage material (MICC) [32].
  • In this report, a vascularized pedicle bone graft was used to treat ANFH, particularly those cases identified as Stage II on the system established by the Japanese Investigation Committee. Surgery involved curettage of necrotic bone, implantation of spongy bone, and application of a vascularized pedicle bone graft [33].

Analytical, diagnostic and therapeutic context of Curettage

  • Thus far, PDT has failed to become established as a routine treatment for small premalignant and malignant skin lesions as it has not proved superior to simple cheaper conventional therapies such as cryotherapy, curettage and cautery, topical chemotherapy with 5-fluorouracil, or surgery [34].
  • Eutectic lidocaine/prilocaine 5% cream and patch may provide satisfactory analgesia for excisional biopsy or curettage with electrosurgery of cutaneous lesions. A randomized, controlled, parallel group study [35].
  • RESULTS: Cesarean delivery was associated with a 13-fold increased risk of emergent hysterectomy when we controlled for previous cesarean delivery, dilation and curettage or abortion before the index pregnancy, use of prostaglandin, and use of pitocin (OR 12.9; 95% CI 5.2, 32.3) [36].
  • METHODS: Twelve patients with severe preeclampsia undergoing an indicated abdominal delivery had endothelin-1 levels measured from plasma specimens drawn from right and left uterine and antecubital veins before delivery and after placenta removal with uterine curettage [37].
  • Major complications occurred in 5% of those undergoing curettage procedures, 41% of women undergoing prostaglandin amnioinfusion, and 17% of those who had hysterotomy as a method of abortion [38].


  1. The immunocytochemical distribution of leukocytic subpopulations in human endometrium. Kamat, B.R., Isaacson, P.G. Am. J. Pathol. (1987) [Pubmed]
  2. Treatment of unicameral bone cysts by curettage and packing with plaster-of-Paris pellets. Peltier, L.F., Jones, R.H. The Journal of bone and joint surgery. American volume. (1978) [Pubmed]
  3. Adjunctive treatment of enchondromas with CO2 laser. Giles, D.W., Miller, S.J., Rayan, G.M. Lasers in surgery and medicine. (1999) [Pubmed]
  4. Treatment of molluscum contagiosum using a lidocaine/prilocaine cream (EMLA) for analgesia. de Waard-van der Spek, F.B., Oranje, A.P., Lillieborg, S., Hop, W.C., Stolz, E. J. Am. Acad. Dermatol. (1990) [Pubmed]
  5. Accelerated recovery from severe preeclampsia: uterine curettage versus nifedipine. Magann, E.F., Bass, J.D., Chauhan, S.P., Perry, K.G., Morrison, J.C., Martin, J.N. J. Soc. Gynecol. Investig. (1994) [Pubmed]
  6. Bone marrow curettage in myelodysplastic disorders. A stimulus for regeneration in disturbed hematopoiesis. Matzner, Y., Polliack, A. JAMA (1981) [Pubmed]
  7. Anastrozole versus tamoxifen treatment in postmenopausal women with endocrine-responsive breast cancer and tamoxifen-induced endometrial pathology. Gerber, B., Krause, A., Reimer, T., Mylonas, I., Makovitzky, J., Kundt, G., Janni, W. Clin. Cancer Res. (2006) [Pubmed]
  8. Immunohistochemical detection of estrogen receptors on paraffin sections of normal, hyperplatic and carcinomatous endometrium. Papadimitriou, C.S., Athanasiadou, S., Stylianidou, A., Bai, M.K., Demoliatis, J., Stephanou, D.G. Oncology (1992) [Pubmed]
  9. Treatment of acute abscesses by incision, curettage and primary suture without antibiotics: a controlled clinical trial. Stewart, M.P., Laing, M.R., Krukowski, Z.H. The British journal of surgery. (1985) [Pubmed]
  10. Endometrial epithelial metaplasias: proliferations frequently misdiagnosed as adenocarcinoma. Report of 89 cases and proposed classification. Hendrickson, M.R., Kempson, R.L. Am. J. Surg. Pathol. (1980) [Pubmed]
  11. Presumed diagnosis of ectopic pregnancy. Barnhart, K.T., Katz, I., Hummel, A., Gracia, C.R. Obstetrics and gynecology. (2002) [Pubmed]
  12. A thrombogenic uterine pack for postpartum hemorrhage. Bobrowski, R.A., Jones, T.B. Obstetrics and gynecology. (1995) [Pubmed]
  13. Effects of tamoxifen on steroid hormone receptors and hormone concentration and the results of DNA analysis by flow cytometry in endometrial carcinoma. Nola, M., Jukić, S., Ilić-Forko, J., Babić, D., Uzarević, B., Petrovecki, M., Suchanek, E., Skrablin, S., Dotlić, S., Marusić, M. Gynecol. Oncol. (1999) [Pubmed]
  14. Primary infertility and uterine anomalies. Heinonen, P.K., Pystynen, P.P. Fertil. Steril. (1983) [Pubmed]
  15. Hyperhidrosis: evolving therapies for a well-established phenomenon. Eisenach, J.H., Atkinson, J.L., Fealey, R.D. Mayo Clin. Proc. (2005) [Pubmed]
  16. Tubal curettage: a new conservative treatment for haemorrhagic interstitial pregnancies. Ayoubi, J.M., Fanchin, R., Olivennes, F., Fernandez, H., Pons, J.C. Hum. Reprod. (2001) [Pubmed]
  17. Induced regeneration of endometrium following curettage for abortion: a comparative study. Farhi, J., Bar-Hava, I., Homburg, R., Dicker, D., Ben-Rafael, Z. Hum. Reprod. (1993) [Pubmed]
  18. Transvaginal Doppler sonography: is there a role for this modality in the evaluation of women with postmenopausal bleeding? Wilailak, S., Jirapinyo, M., Theppisai, U. Maturitas. (2005) [Pubmed]
  19. Uterine curettage following second trimester abortion by extraovular instillation of prostaglandin E2. A prospective-randomized trial. Atad, J., Hallak, M., Fruchter, O., Yshai, D., Auslender, R., Abramovici, H. Eur. J. Obstet. Gynecol. Reprod. Biol. (1999) [Pubmed]
  20. A 17-year review of cryosurgery in the treatment of bone tumors. Marcove, R.C. Clin. Orthop. Relat. Res. (1982) [Pubmed]
  21. The attachment between tooth and gingival tissues after periodic root planing and soft tissue curettage. Caton, J.G., Zander, H.A. J. Periodontol. (1979) [Pubmed]
  22. High-energy, low-dose radiation therapy for aneurysmal bone cyst. Report of a case. Maeda, M., Tateishi, H., Takaiwa, H., Kinoshita, G., Hatano, N., Nakano, K. Clin. Orthop. Relat. Res. (1989) [Pubmed]
  23. Chemical matricectomy with 10% sodium hydroxide for the treatment of ingrowing toenails. Ozdemir, E., Bostanci, S., Ekmekci, P., Gurgey, E. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. (2004) [Pubmed]
  24. Treatment of coccidioidomycosis infection of bone with local amphotericin B suction-irrigation. Report of a case. Stein, S.R., Leukens, C.A., Bagg, R.J. Clin. Orthop. Relat. Res. (1975) [Pubmed]
  25. Economic evaluation of misoprostol in the treatment of early pregnancy failure compared to curettage after an expectant management. Graziosi, G.C., van der Steeg, J.W., Reuwer, P.H., Drogtrop, A.P., Bruinse, H.W., Mol, B.W. Hum. Reprod. (2005) [Pubmed]
  26. Lidocaine versus plain saline for pain relief in fractional curettage: a randomized controlled trial. Chanrachakul, B., Likittanasombut, P., O-Prasertsawat, P., Herabutya, Y. Obstetrics and gynecology. (2001) [Pubmed]
  27. 'Chemical curettage' using intrauterine methotrexate injection. Strohmer, H., Boldizsar, A., Feichtinger, W. Hum. Reprod. (1992) [Pubmed]
  28. Desmoplastic fibroma of bone. A report of eight cases and review of the literature. Gebhardt, M.C., Campbell, C.J., Schiller, A.L., Mankin, H.J. The Journal of bone and joint surgery. American volume. (1985) [Pubmed]
  29. Curettage after mifepristone-induced abortion: frequency, timing, and indications. Allen, R.H., Westhoff, C., De Nonno, L., Fielding, S.L., Schaff, E.A. Obstetrics and gynecology. (2001) [Pubmed]
  30. Immunohistochemical staining properties of PCNA, Ki-67, p53, beta-hCG and HPL in trophoblastic disease. Ozbilim, G., Karaburun, S.P., Zorlu, G., Kaya, R., Erdoğan, G., Karaveli, S. Eur. J. Gynaecol. Oncol. (2000) [Pubmed]
  31. Determination of estrogen and progesterone receptors in endometrial adenocarcinomas. Comparison between dextran-coated charcoal and immunoenzymatic methods on curettage biopsies. Marchal, S., Marchal, C., Hoffstetter, S., Parache, R.M., Pernot, M. Anticancer Res. (1992) [Pubmed]
  32. Residual carcinoma after intracavitary irradiation of endometrial carcinoma, stage I. A study of whole-organ sections. Gröntoft, O., Risberg, B., Sténson, S., Westholm, B. Acta obstetricia et gynecologica Scandinavica. (1982) [Pubmed]
  33. Indications and results of vascularized pedicle iliac bone graft in avascular necrosis of the femoral head. Iwata, H., Torii, S., Hasegawa, Y., Itoh, H., Mizuno, M., Genda, E., Kataoka, Y. Clin. Orthop. Relat. Res. (1993) [Pubmed]
  34. Bowen's disease, solar keratoses and superficial basal cell carcinomas treated by photodynamic therapy using a large-field incoherent light source. Varma, S., Wilson, H., Kurwa, H.A., Gambles, B., Charman, C., Pearse, A.D., Taylor, D., Anstey, A.V. Br. J. Dermatol. (2001) [Pubmed]
  35. Eutectic lidocaine/prilocaine 5% cream and patch may provide satisfactory analgesia for excisional biopsy or curettage with electrosurgery of cutaneous lesions. A randomized, controlled, parallel group study. Gupta, A.K., Sibbald, R.G. J. Am. Acad. Dermatol. (1996) [Pubmed]
  36. Route of delivery as a risk factor for emergent peripartum hysterectomy: a case-control study. Kacmar, J., Bhimani, L., Boyd, M., Shah-Hosseini, R., Peipert, J. Obstetrics and gynecology. (2003) [Pubmed]
  37. The origin of endothelin-1 in patients with severe preeclampsia. Rust, O.A., Bofill, J.A., Zappe, D.H., Hall, J.E., Burnett, J.C., Martin, J.N. Obstetrics and gynecology. (1997) [Pubmed]
  38. Factors influencing morbidity in termination of pregnancy. Harman, C.R., Fish, D.G., Tyson, J.E. Am. J. Obstet. Gynecol. (1981) [Pubmed]
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