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Chemical Compound Review

CCRIS 5557     trichlorochromium

Synonyms: AG-E-12708, HSDB 6341, AC1L2NOT, LS-53418, CTK4D1357, ...
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Disease relevance of trichlorochromium


High impact information on trichlorochromium


Biological context of trichlorochromium


Anatomical context of trichlorochromium

  • This report describes the development of a solid-phase haemadsorption system using chromic chloride-linked, antibody coated erythrocytes [16].
  • Bovine erythrocytes were coated with avidin using a chromic chloride coupling technique and used successfully in an indirect rosette assay to identify and quantitate: (a) T-lymphocyte helper and suppressor subpopulations, and (b) Ia positive B-lymphocyte populations [17].
  • Antibody fractions separated by DEAE chromatography of ascitic fluids were coupled to ox red cells with chromic chloride and compared with polyclonal antibodies for the detection of cell-surface immunoglobulins [18].
  • Sheep red blood cells coated with rabbit anti-erythrocyte antibodies and treated with chromic chloride showed continuous electron-opaque labelling of the cell membrane due to chelation of rabbit IgG with chromium atoms [4].

Associations of trichlorochromium with other chemical compounds


Gene context of trichlorochromium


Analytical, diagnostic and therapeutic context of trichlorochromium


  1. Stabilization of erythrocytes by aldehydes and suitability of chicken IgY for the detection of potato virus X (PVX) in avidin-biotin enhanced reverse passive haemagglutination. Grossmann, A., Eggers-Schumacher, G., Sander, E. J. Immunol. Methods (1995) [Pubmed]
  2. Chemical linkage of erythrocytes and viral antigen in the hemolysis-in-gel (HIG) test for viral antibodies. Steinmann, J., Marzock, H.J. J. Immunol. Methods (1983) [Pubmed]
  3. The detection of heat-aggregated IgG (as a model for immune complexes) by reverse passive haemagglutination using a human monoclonal rheumatoid factor coupled to erythrocytes. Welsh, C.J., Steinitz, M., Clark, M.R., Coombs, R.R. J. Immunol. Methods (1987) [Pubmed]
  4. I. An ultrastructural investigation on erythrocytes and lymphocytes coated with proteins: use of CrCl3 as an electron-dense marker. Mandache, E., Moraru, I., Ghetie, V. J. Immunol. Methods (1978) [Pubmed]
  5. Administration of myelin basic protein-coupled spleen cells prevents experimental allergic encephalitis. Sriram, S., Schwartz, G., Steinman, L. Cell. Immunol. (1983) [Pubmed]
  6. Chromium(III) picolinate produces chromosome damage in Chinese hamster ovary cells. Stearns, D.M., Wise, J.P., Patierno, S.R., Wetterhahn, K.E. FASEB J. (1995) [Pubmed]
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  8. Thyroid antibodies in spontaneous autoimmune thyroiditis in the Buffalo rat. Noble, B., Yoshida, T., Rose, N.R., Bigazzi, P.E. J. Immunol. (1976) [Pubmed]
  9. Immunoglobulin-positive mononuclear cells in human peripheral blood: detection by mixed anti-globulin and direct anti-globulin-rosetting reactions. Haegert, D.G., Coombs, R.R. J. Immunol. (1976) [Pubmed]
  10. Sister chromatid exchanges in Chinese hamster V79 cells treated with the trivalent chromium compounds chromic chloride and chromic oxide. Elias, Z., Schneider, O., Aubry, F., Daniere, M.C., Poirot, O. Carcinogenesis (1983) [Pubmed]
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  12. Ultrastructural damage in chromium picolinate-treated cells: a TEM study. Transmission electron microscopy. Manygoats, K.R., Yazzie, M., Stearns, D.M. J. Biol. Inorg. Chem. (2002) [Pubmed]
  13. In vitro targeting of erythrocytes to cytotoxic T-cells by coupling of Thy-1.2 monoclonal antibody. Chiarantini, L., Droleskey, R., Magnani, M., DeLoach, J.R. Biotechnol. Appl. Biochem. (1992) [Pubmed]
  14. Studies on experimental murine histoplasmosis: host protection and cellular immunity. Burt, W.R., Smith, R.A. Can. J. Microbiol. (1983) [Pubmed]
  15. The effect of humic acid on the toxicity and bioavailability of trivalent chromium. Stackhouse, R.A., Benson, W.H. Ecotoxicol. Environ. Saf. (1989) [Pubmed]
  16. A solid-phase system (SPACE) for the detection and quantification of rotavirus in faeces. Bradburne, A.F., Almeida, J.D., Gardner, P.S., Moosai, R.B., Nash, A.A., Coombs, R.R. J. Gen. Virol. (1979) [Pubmed]
  17. Identification of subpopulations of T lymphocytes and Ia positive B lymphocytes using a rosette assay based upon the biotin-avidin interaction. Mason, R.J., Stewart, K.N., Power, D.A., MacLeod, A.M., Catto, G.R. Immunol. Lett. (1983) [Pubmed]
  18. Properties of monoclonal antibodies to human immunoglobulin kappa and lambda chains. Lowe, J., Hardie, D., Jefferis, R., Ling, N.R., Drysdale, P., Richardson, P., Raykundalia, C., Catty, D., Appleby, P., Drew, R., Maclennan, I.C. Immunology (1981) [Pubmed]
  19. The genotoxicity of chromium(VI) oxide in the wing spot test of Drosophila melanogaster is over 90% due to mitotic recombination. Graf, U., Heo, O.S., Ramirez, O.O. Mutat. Res. (1992) [Pubmed]
  20. Preconception urethane or chromium(III) treatment of male mice: multiple neoplastic and non-neoplastic changes in offspring. Yu, W., Sipowicz, M.A., Haines, D.C., Birely, L., Diwan, B.A., Riggs, C.W., Kasprzak, K.S., Anderson, L.M. Toxicol. Appl. Pharmacol. (1999) [Pubmed]
  21. Differential effect of chromium compounds on the immune response of the African mouth breeder Oreochromis mossambicus (Peters). Arunkumar, R.I., Rajasekaran, P., Michael, R.D. Fish Shellfish Immunol. (2000) [Pubmed]
  22. Analysis of EDTA-chelatable proteins from DNA-protein crosslinks induced by a carcinogenic chromium(VI) in cultured intact human cells. Mattagajasingh, S.N., Misra, H.P. Mol. Cell. Biochem. (1999) [Pubmed]
  23. Tannic acid and chromic chloride-induced binding of protein to red cells: a preliminary study of possible binding sites and reaction mechanisms. Hunt, A.F., Reed, M.I. Medical laboratory sciences. (1990) [Pubmed]
  24. Detection of mouse alloantibodies by rosetting with protein A-coated sheep red blood cells. Sandrin, M.S., Potter, T.A., Morgan, G.M., McKenzie, I.F. Transplantation (1978) [Pubmed]
  25. The relationship between immunization and circulating antigen-specific plaque-forming cells. Falkoff, R.J., Zhu, L.P., Fauci, A.S. Cell. Immunol. (1983) [Pubmed]
  26. Measure of rheumatoid factor in human sera by passive haemagglutination of human erythrocytes carrying immunoglobulin linked by chromic chloride. Koritz, T.N., Gurner, B.W., Chalmers, D.G., Coombs, R.R. J. Immunol. Methods (1980) [Pubmed]
  27. Hemagglutination assay for human serum fibronectin. Bălună, R.G., Barac, D., Tarnavschi, R., Belaşcu, I. J. Immunol. Methods (1985) [Pubmed]
  28. A quantitative determination for the detection of immunoglobulin (IgG) on the surface of platelets. Orsini, F., Gregory, S., Dale, M., Fitzpatrick, J., Cohen, E. Hum. Immunol. (1981) [Pubmed]
  29. Serum chromium of human subjects: effects of chromium supplementation and glucose. Anderson, R.A., Bryden, N.A., Polansky, M.M. Am. J. Clin. Nutr. (1985) [Pubmed]
  30. Microarray analysis of altered gene expression in the TM4 Sertoli-like cell line exposed to chromium(III) chloride. Cheng, R.Y., Alvord, W.G., Powell, D., Kasprzak, K.S., Anderson, L.M. Reprod. Toxicol. (2002) [Pubmed]
  31. Detection of antibodies to tetanus toxoid: comparison of a direct haemagglutination method with a radioimmunoassay. Wang, A.S., Burns, G.F., Kronborg, I.J., Mackay, I.R. J. Clin. Pathol. (1982) [Pubmed]
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