The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Elmiron     (2S,3R,4S,5R)-5-hydroxy-2- [(3R,4S,5R,6R)-6...

Synonyms: AC1L1YAW, CID37720, DAP001025, LS-187046, LS-187658, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Polypentose sulfate


Psychiatry related information on Polypentose sulfate


High impact information on Polypentose sulfate


Chemical compound and disease context of Polypentose sulfate


Biological context of Polypentose sulfate


Anatomical context of Polypentose sulfate


Associations of Polypentose sulfate with other chemical compounds


Gene context of Polypentose sulfate


Analytical, diagnostic and therapeutic context of Polypentose sulfate


  1. Administration of pentosan polysulfate to patients with human immunodeficiency virus-associated Kaposi's sarcoma. Pluda, J.M., Shay, L.E., Foli, A., Tannenbaum, S., Cohen, P.J., Goldspiel, B.R., Adamo, D., Cooper, M.R., Broder, S., Yarchoan, R. J. Natl. Cancer Inst. (1993) [Pubmed]
  2. Pentosan polysulfate as an inhibitor of extracellular HIV-1 Tat. Rusnati, M., Urbinati, C., Caputo, A., Possati, L., Lortat-Jacob, H., Giacca, M., Ribatti, D., Presta, M. J. Biol. Chem. (2001) [Pubmed]
  3. Massive bleeding on a bladder protectant: a case report of pentosan polysulfate sodium-induced coagulopathy. Gill, S., Naiman, S.C., Jamal, A., Vickars, L.M. Arch. Intern. Med. (2002) [Pubmed]
  4. Psychometric validation of the O'leary-Sant interstitial cystitis symptom index in a clinical trial of pentosan polysulfate sodium. Lubeck, D.P., Whitmore, K., Sant, G.R., Alvarez-Horine, S., Lai, C. Urology (2001) [Pubmed]
  5. Inhibition of development of Kaposi's sarcoma-related lesions by a bacterial cell wall complex. Nakamura, S., Sakurada, S., Salahuddin, S.Z., Osada, Y., Tanaka, N.G., Sakamoto, N., Sekiguchi, M., Gallo, R.C. Science (1992) [Pubmed]
  6. Detectable inhibition of heparin-binding growth factor activity in sera from patients treated with pentosan polysulfate. Parker, B.W., Swain, S.M., Zugmaier, G., DeLap, R.L., Lippman, M.E., Wellstein, A. J. Natl. Cancer Inst. (1993) [Pubmed]
  7. Inhibition by pentosan polysulfate (PPS) of heparin-binding growth factors released from tumor cells and blockage by PPS of tumor growth in animals. Zugmaier, G., Lippman, M.E., Wellstein, A. J. Natl. Cancer Inst. (1992) [Pubmed]
  8. Tumor growth dependent on Kaposi's sarcoma-derived fibroblast growth factor inhibited by pentosan polysulfate. Wellstein, A., Zugmaier, G., Califano, J.A., Kern, F., Paik, S., Lippman, M.E. J. Natl. Cancer Inst. (1991) [Pubmed]
  9. Pentosan polysulfate: a review of its use in the relief of bladder pain or discomfort in interstitial cystitis. Anderson, V.R., Perry, C.M. Drugs (2006) [Pubmed]
  10. Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus. Baba, M., Snoeck, R., Pauwels, R., de Clercq, E. Antimicrob. Agents Chemother. (1988) [Pubmed]
  11. Re: cyclosporine A and pentosan polysulfate sodium for the treatment of interstitial cystitis: a randomized comparative study. Buffington, C.A. J. Urol. (2006) [Pubmed]
  12. A pilot clinical trial of oral pentosan polysulfate and oral hydroxyzine in patients with interstitial cystitis. Sant, G.R., Propert, K.J., Hanno, P.M., Burks, D., Culkin, D., Diokno, A.C., Hardy, C., Landis, J.R., Mayer, R., Madigan, R., Messing, E.M., Peters, K., Theoharides, T.C., Warren, J., Wein, A.J., Steers, W., Kusek, J.W., Nyberg, L.M. J. Urol. (2003) [Pubmed]
  13. Effects of pentosan polysulfate sodium on the estrogen-induced pituitary prolactinoma in Fischer 344 rats. Mucha, S., Melen-Mucha, G., Stepien, T., Godlewski, A., Stepien, H. Oncol. Rep. (2002) [Pubmed]
  14. Malaria sporozoites and circumsporozoite proteins bind specifically to sulfated glycoconjugates. Pancake, S.J., Holt, G.D., Mellouk, S., Hoffman, S.L. J. Cell Biol. (1992) [Pubmed]
  15. High-affinity binding sites for heparin generated on leukocytes during apoptosis arise from nuclear structures segregated during cell death. Gebska, M.A., Titley, I., Paterson, H.F., Morilla, R.M., Davies, D.C., Gruszka-Westwood, A.M., Kakkar, V.V., Eccles, S., Scully, M.F. Blood (2002) [Pubmed]
  16. Heparan sulfates and coxsackievirus-adenovirus receptor: each one mediates coxsackievirus B3 PD infection. Zautner, A.E., Körner, U., Henke, A., Badorff, C., Schmidtke, M. J. Virol. (2003) [Pubmed]
  17. Absence of transplacental passage of pentosan polysulfate during mid trimester of pregnancy. Forestier, F., Fischer, A.M., Daffos, F., Beguin, S., Diner, H. Thromb. Haemost. (1986) [Pubmed]
  18. A system for the enhancement of adenovirus mediated gene transfer to uro-epithelium. Lin, L.F., Zhu, G., Yoo, J.J., Soker, S., Sukhatme, V.P., Atala, A. J. Urol. (2002) [Pubmed]
  19. Retardation of articular cartilage degradation by glycosaminoglycan polysulfate, pentosan polysulfate, and DH-40J in the rat air pouch model. Francis, D.J., Forrest, M.J., Brooks, P.M., Ghosh, P. Arthritis Rheum. (1989) [Pubmed]
  20. Production of tissue inhibitor of metalloproteinases 3 is selectively enhanced by calcium pentosan polysulfate in human rheumatoid synovial fibroblasts. Takizawa, M., Ohuchi, E., Yamanaka, H., Nakamura, H., Ikeda, E., Ghosh, P., Okada, Y. Arthritis Rheum. (2000) [Pubmed]
  21. Pentosan polysulfate decreases proliferation and net extracellular matrix production in mouse mesangial cells. Elliot, S.J., Striker, L.J., Stetler-Stevenson, W.G., Jacot, T.A., Striker, G.E. J. Am. Soc. Nephrol. (1999) [Pubmed]
  22. Pentosan polysulfate protects brain endothelial cells against bacterial lipopolysaccharide-induced damages. Veszelka, S., P??szt??i, M., Farkas, A.E., Krizbai, I., Dung, N.T., Niwa, M., Abrah??m, C.S., Deli, M.A. Neurochem. Int. (2007) [Pubmed]
  23. Glycosaminoglycans inhibit degradation of insulin-like growth factor-binding protein-5. Arai, T., Arai, A., Busby, W.H., Clemmons, D.R. Endocrinology (1994) [Pubmed]
  24. Epidural hematoma after epidural steroid injection: a possible association with use of pentosan polysulfate sodium. Siddiqui, M.N., Ranasinghe, J.S., Siddiqui, S. Anesthesiology (2001) [Pubmed]
  25. Pentosan polysulfate as an inhibitor of calcium oxalate crystal growth. Martin, X., Werness, P.G., Bergert, J.H., Smith, L.H. J. Urol. (1984) [Pubmed]
  26. Highly sulfated glycosaminoglycans inhibit aggrecanase degradation of aggrecan by bovine articular cartilage explant cultures. Munteanu, S.E., Ilic, M.Z., Handley, C.J. Matrix Biol. (2002) [Pubmed]
  27. Heparin stimulates fibrinolysis in mesothelial cells by selective induction of tissue-plasminogen activator but not plasminogen activator inhibitor-1 synthesis. Grulich-Henn, J., Preissner, K.T., Müller-Berghaus, G. Thromb. Haemost. (1990) [Pubmed]
  28. Calcium pentosan polysulfate inhibits the catabolism of aggrecan in articular cartilage explant cultures. Munteanu, S.E., Ilic, M.Z., Handley, C.J. Arthritis Rheum. (2000) [Pubmed]
  29. Modulation of heparin cofactor II function by S protein (vitronectin) and formation of a ternary S protein-thrombin-heparin cofactor II complex. Preissner, K.T., Sié, P. Thromb. Haemost. (1988) [Pubmed]
  30. Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein. Wong, C., Xiong, L.W., Horiuchi, M., Raymond, L., Wehrly, K., Chesebro, B., Caughey, B. EMBO J. (2001) [Pubmed]
  31. The effects of orally administered calcium pentosan polysulfate on inflammation and cartilage degradation produced in rabbit joints by intraarticular injection of a hyaluronate-polylysine complex. Smith, M.M., Ghosh, P., Numata, Y., Bansal, M.K. Arthritis Rheum. (1994) [Pubmed]
  32. Pentosan polysulfate prevents glomerular hypertension and structural injury despite persisting hypertension in 5/6 nephrectomy rats. Bobadilla, N.A., Tack, I., Tapia, E., Sánchez-Lozada, L.G., Santamaría, J., Jiménez, F., Striker, L.J., Striker, G.E., Herrera-Acosta, J. J. Am. Soc. Nephrol. (2001) [Pubmed]
  33. Effect on sperm-induced activation current and increase of cytosolic Ca2+ by agents that modify the mobilization of [Ca2+]i. I. Heparin and pentosan polysulfate. Mohri, T., Ivonnet, P.I., Chambers, E.L. Dev. Biol. (1995) [Pubmed]
WikiGenes - Universities