Disease relevance of Phosphide

• Intravascular hemolysis in aluminium phosphide poisoning [1].
• Methemoglobinemia with aluminum phosphide poisoning [2].
• A child with hepatic and renal failure caused by aluminum phosphide [3].
• As initial signs and symptoms of intoxication from phosphine gas may be nonspecific and transient, there is a need for improved recognition of the potential hazards associated with phosphide fumigants and phosphine gas [4].
• CONCLUSION: Pseudomonas aeruginosa accumulated nickel as its phosphide and carbide crystal mostly in the cell envelope region, indicating the predominant role of phosphoryl and carboxyl/carbonyl groups of cell wall/membrane components in cation sequestration [5].

High impact information on Phosphide

• A series of gas-phase nucleophilic substitution reactions at sulfur of methanesulfinyl derivatives by small anions (chloride, cyanide, hydroxide, methoxide, amide, and phosphide, identical to the leaving group in each case) were examined by Hartree-Fock, MP2, and DFT computations [6].
• The article integrates a traditional pathologic study of toxicant-induced pulmonary carcinogenesis with an immunohistologic assessment of oxidative stress, thereby determining a potential mechanism of action of a toxicant, specifically indium phosphide [7].
• Phosphine (PH3), from hydrolysis of metal phosphides, is an important insecticide (aluminum phosphide) and rodenticide (zinc phosphide) and is considered genotoxic and cytotoxic in mammals [8].
• Occupational exposure to aluminium phosphide and phosphine gas? A suspected case report and review of the literature [4].
• The manufacture and application of aluminium phosphide fumigants pose risks of inhalation exposure to phosphine gas [4].

Chemical compound and disease context of Phosphide

• The results showed that high-dose males developed significantly increased incidences of coronary and renal arteritis over controls in 2 of the 9 studies (indium phosphide and cobalt sulfate heptahydrate), while marginal increases in arteritis incidence was detected in 2 additional studies (vanadium pentoxide and gallium arsenide) [9].

Biological context of Phosphide

• A review of the data on human exposures to phosphide fumigants identifies both pesticide applicators and individuals in the vicinity of application to be at risk of accidental exposure and injury from phosphine inhalation [4].
• Fumigation using aluminum phosphide pellets was the main method for managing these insect pests in elevators in the USA [10].
• Free radical scavengers & lipid peroxidation in acute aluminium phosphide poisoning [11].
• Epidemiology of hydrogen phosphide exposures in humans reported to the poison center in Mainz, Germany, 1983-2003 [12].
• Significance of heart rate response in shock due to aluminium phosphide poisoning [13].

Anatomical context of Phosphide

• Investigation of a fatality from nonoccupational aluminum phosphide exposure: measurement of aluminum in tissue and body fluids as a marker of exposure [14].
• Aluminum phosphide poisoning is common in the rural belt of Northern India. The release of cytotoxic phosphine gas primarily affects the heart, lungs, gastrointestinal tract and kidneys, although all organs can be involved [15].
• It seems evident that aluminium phosphide exposure significantly enhanced neuronal lipoperoxidative damage with concomitant alterations in the antioxidant defence status thus having serious bearing on the functional and structural status of the central nervous system [16].
• We report a 24-year-old woman and a 58-year-old man who developed short-segment esophageal strictures in the upper and mid esophagus two weeks after ingestion of aluminium phosphide tablets [17].

Associations of Phosphide with other chemical compounds

• Synthesis and optical properties of gallium phosphide nanotubes [18].
• Gallium phosphide nanotubes with zinc blende structure were synthesized for the first time [18].
• Fourier transform infrared spectroscopy (FTIR) of the 2-methylpiperidine indicated that at reaction conditions a piperidinium ion intermediate was formed on both the sulfide and the phosphide [19].

Gene context of Phosphide

• A decline in the activity of glutathione reductase was also observed, however, no change was seen in the activity of glutathione peroxidase following aluminium phosphide administration [16].
• Cytochrome-c oxidase inhibition in 26 aluminum phosphide poisoned patients [20].
• This report describes the occurrence of intravascular hemolysis with aluminium phosphide poisoning in a patient with normal G-6-PD levels [1].
• Free radicals scavengers superoxide dismuatase (SOD) and catalase and lipid peroxidation were studied in 45 patients of aluminium phosphide poisoning irrespective of age and sex admitted to a hospital in north India during the January 1992 to December 1993 [11].

Analytical, diagnostic and therapeutic context of Phosphide

• The surface reactions of atomic and molecular oxygen with carbon phosphide films have been studied using X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM) [21].
• Gallium phosphide nanowires with a most probable diameter of approximately 20.0 nm and more than 10 microns in length have been synthesized by pulsed laser vaporization of a heated GaP/5% Au target [22].
• Electron and hole transfer from indium phosphide quantum dots [23].

References