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Chemical Compound Review

Sulphapyridin     4-amino-N-pyridin-2-yl- benzenesulfonamide

Synonyms: Haptocil, Plurazol, Pyriamid, Sulfidin, Adiplon, ...
 
 
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Disease relevance of Sulphapyridine

 

High impact information on Sulphapyridine

 

Chemical compound and disease context of Sulphapyridine

 

Biological context of Sulphapyridine

 

Anatomical context of Sulphapyridine

 

Associations of Sulphapyridine with other chemical compounds

 

Gene context of Sulphapyridine

 

Analytical, diagnostic and therapeutic context of Sulphapyridine

References

  1. Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn's disease. Klotz, U., Maier, K., Fischer, C., Heinkel, K. N. Engl. J. Med. (1980) [Pubmed]
  2. Dermatitis herpetiformis: the skin and the gut. Katz, S.I., Hall, R.P., Lawley, T.J., Strober, W. Ann. Intern. Med. (1980) [Pubmed]
  3. Desensitization of patients with inflammatory bowel disease to sulfasalazine. Taffet, S.L., Das, K.M. Am. J. Med. (1982) [Pubmed]
  4. Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: a study to determine the active therapeutic moiety of sulphasalazine. van Hees, P.A., Bakker, J.H., van Tongeren, J.H. Gut (1980) [Pubmed]
  5. Acetylation polymorphism of sulfapyridine in patients with ulcerative colitis and Crohn's disease. Das, K.M., Eastwood, M.A. Clin. Pharmacol. Ther. (1975) [Pubmed]
  6. Sulfapyridine appearance in plasma after salicylazosulfapyridine. Another simple measure of intestinal transit. Kellow, J.E., Borody, T.J., Phillips, S.F., Haddad, A.C., Brown, M.L. Gastroenterology (1986) [Pubmed]
  7. Small bowel absorption of sulfasalazine and its hepatic metabolism in human beings, cats, and rats. Das, K.M., Chowdhury, J.R., Zapp, B., Fara, J.W. Gastroenterology (1979) [Pubmed]
  8. Treatment with sulfasalazine or sulfapyridine, but not 5-aminosalicyclic acid, inhibits basic fibroblast growth factor-induced endothelial cell chemotaxis. Volin, M.V., Harlow, L.A., Woods, J.M., Campbell, P.L., Amin, M.A., Tokuhira, M., Koch, A.E. Arthritis Rheum. (1999) [Pubmed]
  9. Inhibition of cell mediated cytotoxicity by sulphasalazine: effect of in vivo treatment with 5-aminosalicylic acid and sulphasalazine on in vitro natural killer cell activity. Aparicio-Pagés, M.N., Verspaget, H.W., Hafkenscheid, J.C., Crama-Bohbouth, G.E., Peña, A.S., Weterman, I.T., Lamers, H.W. Gut (1990) [Pubmed]
  10. Inhibition of leucocyte motility by drugs used in ulcerative colitis. Rhodes, J.M., Bartholomew, T.C., Jewell, D.P. Gut (1981) [Pubmed]
  11. Nutritional status in patients with dermatitis herpetiformis. Gawkrodger, D.J., Ferguson, A., Barnetson, R.S. Am. J. Clin. Nutr. (1988) [Pubmed]
  12. Pulmonary infiltrates and eosinophilia associated with sulfasalazine. Wang, K.K., Bowyer, B.A., Fleming, C.R., Schroeder, K.W. Mayo Clin. Proc. (1984) [Pubmed]
  13. Effect of sulfasalazine and its analogs on fertility in male rats. Didolkar, A.K., Keizer-Zucker, A., Sundaram, K., Bardin, C.W., Agback, H., Johansson, E.D. Contraception. (1988) [Pubmed]
  14. Sulfasalazine and dermatitis herpetiformis. Willsteed, E., Lee, M., Wong, L.C., Cooper, A. Australas. J. Dermatol. (2005) [Pubmed]
  15. Reversible male infertility due to sulphasalazine: studies in man and rat. O'Moráin, C., Smethurst, P., Doré, C.J., Levi, A.J. Gut (1984) [Pubmed]
  16. Salivary excretion and pharmacokinetics of sulfapyridine after sulfasalazine. Bates, T.R., Blumenthal, H.P., Pieniaszek, H.J. Clin. Pharmacol. Ther. (1977) [Pubmed]
  17. Clinical pharmacokinetics of sulphasalazine. Das, K.M., Dubin, R. Clinical pharmacokinetics. (1976) [Pubmed]
  18. Clinical pharmacokinetics of sulphasalazine, its metabolites and other prodrugs of 5-aminosalicylic acid. Klotz, U. Clinical pharmacokinetics. (1985) [Pubmed]
  19. Sulphasalazine and male infertility: reversibility and possible mechanism. Toovey, S., Hudson, E., Hendry, W.F., Levi, A.J. Gut (1981) [Pubmed]
  20. Sulphasalazine: a review of 40 years' experience. Watkinson, G. Drugs (1986) [Pubmed]
  21. Effect of sulphasalazine and sulphapyridine on neutrophil superoxide production: role of cytosolic free calcium. Kanerud, L., Hafström, I., Ringertz, B. Ann. Rheum. Dis. (1990) [Pubmed]
  22. Review article: balsalazide therapy in ulcerative colitis. Ragunath, K., Williams, J.G. Aliment. Pharmacol. Ther. (2001) [Pubmed]
  23. Increased suppressor cell activity in inflammatory bowel disease. Holdstock, G., Chastenay, B.F., Krawitt, E.L. Gut (1981) [Pubmed]
  24. The effect of age and acetylator phenotype on the pharmacokinetics of sulfasalazine in patients with rheumatoid arthritis. Taggart, A.J., McDermott, B.J., Roberts, S.D. Clinical pharmacokinetics. (1992) [Pubmed]
  25. Dermatitis herpetiformis: effects of sulfones and sulfonamides on neutrophil myeloperoxidase-mediated iodination and cytotoxicity. Kazmierowski, J.A., Ross, J.E., Peizner, D.S., Wuepper, K.D. J. Clin. Immunol. (1984) [Pubmed]
  26. N-acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis. Ricart, E., Taylor, W.R., Loftus, E.V., O'Kane, D., Weinshilboum, R.M., Tremaine, W.J., Harmsen, W.S., Zinsmeister, A.R., Sandborn, W.J. Am. J. Gastroenterol. (2002) [Pubmed]
  27. Modulation of cytokine release from human monocytes by drugs used in the therapy of inflammatory bowel diseases. Bruin, K.F., Hommes, D.W., Jansen, J., Tytgat, G.N., Wouter ten Cate, J., van Deventer, S.J. European journal of gastroenterology & hepatology. (1995) [Pubmed]
  28. Inhibition of nuclear factor kappa B and induction of apoptosis in T-lymphocytes by sulfasalazine. Liptay, S., Bachem, M., Häcker, G., Adler, G., Debatin, K.M., Schmid, R.M. Br. J. Pharmacol. (1999) [Pubmed]
  29. Inhibition of platelet thromboxane synthetase by sulfasalazine. Stenson, W.F., Lobos, E. Biochem. Pharmacol. (1983) [Pubmed]
  30. Is the pig a good animal model for studying the human ileal brake? Dobson, C.L., Hinchcliffe, M., Davis, S.S., Chauhan, S., Wilding, I.R. Journal of pharmaceutical sciences. (1998) [Pubmed]
  31. Determination of salicylazosulphapyridine and sulphapyridine in plasma using high-performance liquid chromatography. Lanbeck, K., Lindström, B. J. Chromatogr. (1978) [Pubmed]
  32. Effects of sulphapyridine on sperm transport through the rat epididymis and contractility of the epididymal duct. Chaturapanich, G., Sujarit, K., Pholpramool, C. J. Reprod. Fertil. (1999) [Pubmed]
  33. Electron-capture gas chromatography of sulphapyridine and its N4-acetyl metabolite in serum after extraction methylation. Glyllenhaal, O., Näslund, B., Hartvig, P. J. Chromatogr. (1978) [Pubmed]
 
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