Chemical Compound Review:
CINANSERIN (E)-N-[2-(3- dimethylaminopropylsulfanyl) ph...
Synonyms:
Cinaserin, Cinanserina, Cinanserine, Cinanserinum, CHEMBL18786, ...
- Experimental CNS ischemia: serotonin antagonists reduce or prevent damage. Zivin, J.A., Venditto, J.A. Neurology (1984)
- Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro. Chen, L., Gui, C., Luo, X., Yang, Q., Günther, S., Scandella, E., Drosten, C., Bai, D., He, X., Ludewig, B., Chen, J., Luo, H., Yang, Y., Yang, Y., Zou, J., Thiel, V., Chen, K., Shen, J., Shen, X., Jiang, H. J. Virol. (2005)
- Antimyoclonic properties of S2 serotonin receptor antagonists in the rat. Pranzatelli, M.R., Snodgrass, S.R. Neuropharmacology (1986)
- Effects of serotonergic agonists and antagonists on the locomotor activity of neonatal rats. Lucot, J.B., Seiden, L.S. Pharmacol. Biochem. Behav. (1986)
- Picomolar affinity of 125I-SCH 23982 for D1 receptors in brain demonstrated with digital subtraction autoradiography. Altar, C.A., Marien, M.R. J. Neurosci. (1987)
- 3H-DOB (4-bromo-2,5-dimethoxyphenylisopropylamine) labels a guanyl nucleotide-sensitive state of cortical 5-HT2 receptors. Lyon, R.A., Davis, K.H., Titeler, M. Mol. Pharmacol. (1987)
- Specific binding sites for 5-hydroxytryptamine on rat blood platelets. Drummond, A.H., Gordon, J.L. Biochem. J. (1975)
- Cocaine-induced convulsions: pharmacological antagonism at serotonergic, muscarinic and sigma receptors. Ritz, M.C., George, F.R. Psychopharmacology (Berl.) (1997)
- Mediation by 5-HT3 receptors of an excitatory effect of 5-HT on dorsal vagal preganglionic neurones in anaesthetized rats: an ionophoretic study. Wang, Y., Ramage, A.G., Jordan, D. Br. J. Pharmacol. (1996)
- Myoclonus in the rat induced by p,p'-DDT and the role of altered monoamine function. Pratt, J.A., Rothwell, J., Jenner, P., Marsden, C.D. Neuropharmacology (1985)
- Blockade of 5-HT2 receptors protects against impairment of working memory following transient forebrain ischemia in the rat. Ohno, M., Yamamoto, T., Watanabe, S. Neurosci. Lett. (1991)
- Hyperalgesia produced by the intrathecal administration of tryptamine to rats. Larson, A.A. Brain Res. (1983)
- Serotonergic mediation of cocaine seizures in mice. Schechter, M.D., Meehan, S.M. Pharmacol. Biochem. Behav. (1995)
- Selective labelling of high affinity 5-hydroxytryptamine1 receptors in whole rat brain. Yoshikawa, S., Ishitani, R. Neuropharmacology (1984)
- The hypophagic effect of restraint stress in rats can be mediated by 5-HT2 receptors in the paraventricular nucleus of the hypothalamus. Grignaschi, G., Mantelli, B., Samanin, R. Neurosci. Lett. (1993)
- Some pharmacological actions of 2,5-dimethoxy-4-ethylamphetamine (DOET) in rats and mice. Huang, J., Ho, B.T. J. Pharm. Pharmacol. (1975)
- Protective effect of the serotonin receptor antagonist cinanserin in two canine models of pacing-induced myocardial ischemia. Grover, G.J., Parham, C.S., Youssef, S., Ogletree, M.L. Pharmacology (1995)
- p-Chloroamphetamine-induced hyperthermia pharmacologically distinct from fenfluramine-induced hyperthermia. Quock, R.M., Weick, B.G. J. Pharm. Pharmacol. (1979)
- Studies on the mesolimbic loop of antinociception--II. A serotonin-enkephalin interaction in the nucleus accumbens. Xuan, Y.T., Shi, Y.S., Zhou, Z.F., Han, J.S. Neuroscience (1986)
- Inhibition of phrenic and sympathetic vasomotor neurons in cats by the serotonin analog 5-methoxy-N,N-dimethyltryptamine. Lalley, P.M. J. Pharmacol. Exp. Ther. (1982)
- Proceedings: The effects of cinanserin and phentolamine applied by microiontophoresis in the spinal cord. Barasi, S., Roberts, M.H. Br. J. Pharmacol. (1975)
- Habituation of tactile startle is altered by drugs acting on serotonin-2 receptors. Geyer, M.A., Tapson, G.S. Neuropsychopharmacology (1988)
- In vitro characterisation of dopamine receptors in the superior colliculus of the rat. Weller, M.E., Rose, S., Jenner, P., Marsden, C.D. Neuropharmacology (1987)
- Agonist and antagonist properties of serotonergic compounds in pigeons trained to discriminate either quipazine or L-5-hydroxytryptophan. Yamamoto, T., Walker, E.A., Woods, J.H. J. Pharmacol. Exp. Ther. (1991)
- Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors. Pazos, A., Cortés, R., Palacios, J.M. Brain Res. (1985)
- Distribution and function of brain natriuretic peptide in the stomach and small intestine of the rat. Sharkey, K.A., Gall, D.G., MacNaughton, W.K. Regul. Pept. (1991)
- The pharmacology of the hypothermic response in mice to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). A model of presynaptic 5-HT1 function. Goodwin, G.M., De Souza, R.J., Green, A.R. Neuropharmacology (1985)
- Central 5-hydroxytryptamine (5-HT) receptors in blood pressure regulation. Dabiré, H. Thérapie. (1991)
- Rapid desensitization and resensitization of 5-HT2 receptor mediated phosphatidyl inositol hydrolysis by serotonin agonists in quiescent calf aortic smooth muscle cells. Pauwels, P.J., Van Gompel, P., Leysen, J.E. Life Sci. (1990)
- Delayed functional disability in dystrophic chickens receiving chemotherapy. Hudecki, M.S., Pollina, C.M., Bhargava, A.K., Hudecki, R.S., Heffner, R.R. Muscle Nerve (1979)
- Is there a serotonergic tonic descending inhibition on the responses of dorsal horn convergent neurons to C-fibre inputs? Rivot, J.P., Calvino, B., Besson, J.M. Brain Res. (1987)
- The effect of modification of 5-hydroxytryptamine function in nucleus raphe magnus on nociceptive threshold. Llewelyn, M.B., Azami, J., Roberts, M.H. Brain Res. (1984)
- The excitability and rhythm of medullary respiratory neurons in the cat are altered by the serotonin receptor agonist 5-methoxy-N,N, dimethyltryptamine. Lalley, P.M. Brain Res. (1994)