The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Catinona     (2S)-2-amino-1-phenyl-propan- 1-one

Synonyms: Cathinone, Cathinonum, Norephedrone, d-Cathinone, l-Cathinone, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of l-Cathinone


Psychiatry related information on l-Cathinone


High impact information on l-Cathinone


Chemical compound and disease context of l-Cathinone


Biological context of l-Cathinone


Anatomical context of l-Cathinone


Associations of l-Cathinone with other chemical compounds


Gene context of l-Cathinone

  • Histopathological examination of testes revealed degeneration of interstitial tissue, cellular infiltration and atrophy of Sertoli and Leydig's cells in cathinone treated animals [3].
  • The increase in plasma ACTH induced by the tail-flick test at 30 min and 24 h was significantly enhanced by cathinone, in a naloxone-reversible way [27].

Analytical, diagnostic and therapeutic context of l-Cathinone


  1. Pharmacodynamics and pharmacokinetics of khat: a controlled study. Widler, P., Mathys, K., Brenneisen, R., Kalix, P., Fisch, H.U. Clin. Pharmacol. Ther. (1994) [Pubmed]
  2. Effects of amphetamine derivatives and cathinone on noradrenaline-evoked contractions of rat right ventricle. Cleary, L., Buber, R., Docherty, J.R. Eur. J. Pharmacol. (2002) [Pubmed]
  3. An evaluation of the male reproductive toxicity of cathinone. Islam, M.W., Tariq, M., Ageel, A.M., el-Feraly, F.S., al-Meshal, I.A., Ashraf, I. Toxicology (1990) [Pubmed]
  4. Methcathinone: a new postindustrial drug. Belhadj-Tahar, H., Sadeg, N. Forensic Sci. Int. (2005) [Pubmed]
  5. Re: cathinone: a new differential in the diagnosis of pregnancy induced hypertension. Kuczkowski, K.M. East African medical journal. (2004) [Pubmed]
  6. Conditioned place preference produced by the psychostimulant cathinone. Schechter, M.D., Meehan, S.M. Eur. J. Pharmacol. (1993) [Pubmed]
  7. Role of instrumental learning in tolerance to cathinone hypophagia. Wolgin, D.L., Munoz, J.R. Behav. Neurosci. (2006) [Pubmed]
  8. Methcathinone: a new and potent amphetamine-like agent. Glennon, R.A., Yousif, M., Naiman, N., Kalix, P. Pharmacol. Biochem. Behav. (1987) [Pubmed]
  9. Chiral resolution of cationic drugs of forensic interest by capillary electrophoresis with mixtures of neutral and anionic cyclodextrins. Lurie, I.S., Klein, R.F., Dal Cason, T.A., LeBelle, M.J., Brenneisen, R., Weinberger, R.E. Anal. Chem. (1994) [Pubmed]
  10. Khat chewing delays gastric emptying of a semi-solid meal. Heymann, T.D., Bhupulan, A., Zureikat, N.E., Bomanji, J., Drinkwater, C., Giles, P., Murray-Lyon, I.M. Aliment. Pharmacol. Ther. (1995) [Pubmed]
  11. Effects of cathinone and amphetamine on the neurochemistry of dopamine in vivo. Pehek, E.A., Schechter, M.D., Yamamoto, B.K. Neuropharmacology (1990) [Pubmed]
  12. Further evidence for an amphetamine-like mechanism of action of the alkaloid cathinone. Kalix, P., Glennon, R.A. Biochem. Pharmacol. (1986) [Pubmed]
  13. The releasing effect of the isomers of the alkaloid cathinone at central and peripheral catecholamine storage sites. Kalix, P. Neuropharmacology (1986) [Pubmed]
  14. Differential effects of nicotine but not cathinone on motor activity of P and NP rats. Gordon, T.L., Meehan, S.M., Schechter, M.D. Pharmacol. Biochem. Behav. (1993) [Pubmed]
  15. Khat chewing is a risk factor for acute myocardial infarction: a case-control study. Al-Motarreb, A., Briancon, S., Al-Jaber, N., Al-Adhi, B., Al-Jailani, F., Salek, M.S., Broadley, K.J. British journal of clinical pharmacology. (2005) [Pubmed]
  16. Amphetamine-like effects in humans of the khat alkaloid cathinone. Brenneisen, R., Fisch, H.U., Koelbing, U., Geisshüsler, S., Kalix, P. British journal of clinical pharmacology. (1990) [Pubmed]
  17. Metabolism of cathinone to d-norpseudoephedrine in humans. Guantai, A.N., Maitai, C.K. Journal of pharmaceutical sciences. (1983) [Pubmed]
  18. Actions of amphetamine derivatives and cathinone at the noradrenaline transporter. Cleary, L., Docherty, J.R. Eur. J. Pharmacol. (2003) [Pubmed]
  19. Cathinone: an investigation of several N-alkyl and methylenedioxy-substituted analogs. Dal Cason, T.A., Young, R., Glennon, R.A. Pharmacol. Biochem. Behav. (1997) [Pubmed]
  20. Effect of cathinone on chick embryo heart. Maitai, C.K. J. Pharm. Pharmacol. (1981) [Pubmed]
  21. Comparison of immune functional parameters following in vitro exposure to natural and synthetic amphetamines. House, R.V., Thomas, P.T., Bhargava, H.N. Immunopharmacology and immunotoxicology. (1994) [Pubmed]
  22. The effect of chewing Khat leaves on human mood. Hassan, N.A., Gunaid, A.A., El-Khally, F.M., Murray-Lyon, I.M. Saudi medical journal. (2002) [Pubmed]
  23. Involvement of monoaminergic and peptidergic components in cathinone-induced analgesia. Della Bella, D., Carenzi, A., Frigeni, V., Reggiani, A., Zambon, A. Eur. J. Pharmacol. (1985) [Pubmed]
  24. Cathinone (Khat) and methcathinone (CAT) in urine specimens: a gas chromatographic-mass spectrometric detection procedure. Paul, B.D., Cole, K.A. Journal of analytical toxicology. (2001) [Pubmed]
  25. A behavioral comparison of Nexus, cathinone, BDB, and MDA. Bronson, M.E., Jiang, W., DeRuiter, J., Clark, C.R. Pharmacol. Biochem. Behav. (1995) [Pubmed]
  26. Coronary and aortic vasoconstriction by cathinone, the active constituent of khat. Al-Motarreb, A.L., Broadley, K.J. Autonomic & autacoid pharmacology. (2003) [Pubmed]
  27. Prolonged analgesia induced by cathinone. The role of stress and opioid and nonopioid mechanisms. Nencini, P., Ahmed, A.M., Anania, M.C., Moscucci, M., Paroli, E. Pharmacology (1984) [Pubmed]
  28. Clozapine attenuates the locomotor sensitisation and the prepulse inhibition deficit induced by a repeated oral administration of Catha edulis extract and cathinone in rats. Banjaw, M.Y., Fendt, M., Schmidt, W.J. Behav. Brain Res. (2005) [Pubmed]
  29. Khat consumption: a pharmacological review. Nencini, P., Ahmed, A.M. Drug and alcohol dependence. (1989) [Pubmed]
WikiGenes - Universities