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Chemical Compound Review

DPCP     2,3-diphenylcycloprop-2-en-1- one

Synonyms: Diphencyprone, SureCN105663, AG-H-58347, ACMC-20al56, CHEBI:53074, ...
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Disease relevance of NSC 57541


High impact information on NSC 57541


Chemical compound and disease context of NSC 57541


Biological context of NSC 57541

  • In the treated patients with a good response to diphencyprone, the mean T4/T8 ratio was 1:1, while in the patients with poor or no response to treatment, the ratio was 0 [15].
  • The antioxidants were prepared by cyclization of pyridines and diazines with diphenylcyclopropenone followed by introduction of the O-substituent [16].

Anatomical context of NSC 57541


Associations of NSC 57541 with other chemical compounds


Gene context of NSC 57541


Analytical, diagnostic and therapeutic context of NSC 57541


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  16. Inhibition of lipid peroxidation mediated by indolizines. Nasir, A.I., Gundersen, L.L., Rise, F., Antonsen, O., Kristensen, T., Langhelle, B., Bast, A., Custers, I., Haenen, G.R., Wikström, H. Bioorg. Med. Chem. Lett. (1998) [Pubmed]
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  27. Exogenous topical lactoferrin inhibits allergen-induced Langerhans cell migration and cutaneous inflammation in humans. Griffiths, C.E., Cumberbatch, M., Tucker, S.C., Dearman, R.J., Andrew, S., Headon, D.R., Kimber, I. Br. J. Dermatol. (2001) [Pubmed]
  28. Fexofenadine, an H1-receptor antagonist, partially but rapidly inhibits the itch of contact dermatitis induced by diphenylcyclopropenone in patients with alopecia areata. Katagiri, K., Arakawa, S., Hatano, Y., Fujiwara, S. J. Dermatol. (2006) [Pubmed]
  29. UV exposure reduces immunization rates and promotes tolerance to epicutaneous antigens in humans: relationship to dose, CD1a-DR+ epidermal macrophage induction, and Langerhans cell depletion. Cooper, K.D., Oberhelman, L., Hamilton, T.A., Baadsgaard, O., Terhune, M., LeVee, G., Anderson, T., Koren, H. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  30. Cytokine mRNA levels in Alopecia areata before and after treatment with the contact allergen diphenylcyclopropenone. Hoffmann, R., Wenzel, E., Huth, A., van der Steen, P., Schäufele, M., Henninger, H.P., Happle, R. J. Invest. Dermatol. (1994) [Pubmed]
  31. Raman spectroscopic study on solvation of diphenylcyclopropenone and phenol blue in room temperature ionic liquids. Fujisawa, T., Fukuda, M., Terazima, M., Kimura, Y. The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment & general theory. (2006) [Pubmed]
  32. Phenotype of Langerhans cells in human afferent skin lymph derived from allergic contact dermatitis. Brand, C.U., Gerber, H.A., Hunziker, T., Schaffner, T., Limat, A., Brathen, L.R. Exp. Dermatol. (1993) [Pubmed]
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