Chemical Compound Review:
SureCN114651 2-amino-9-[(2R,3R,4S,5R)-3,4- dihydroxy-5...
Synonyms:
SureCN437750, SureCN529666, CCRIS 8242, AG-J-04337, CHEMBL1688964, ...
Hamm,
Rajguru,
Downs,
Cholera,
Nunomura,
Chiba,
Lippa,
Cras,
Kalaria,
Takeda,
Honda,
Smith,
Perry,
Hamada,
Nakata,
Nakae,
Kobayashi,
Akai,
Konishi,
Okada,
Shibata,
Hosokawa,
Moriuchi,
Bialkowski,
Bialkowska,
Anderson,
Kasprzak,
Bialkowski,
Kasprzak,
Helbock,
Beckman,
Shigenaga,
Walter,
Woodall,
Yeo,
Ames,
Klinz,
Schmidt,
Schinköthe,
Arnhold,
Desai,
Popken,
Brixius,
Schwinger,
Mehlhorn,
Staib,
Addicks,
Bloch,
Park,
Park,
Gwak,
Zhang,
Perry,
Smith,
Robertson,
Olson,
Graham,
Montine,
Bialkowski,
Kasprzak,
Nunomura,
Chiba,
Kosaka,
Takeda,
Castellani,
Smith,
Perry,
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- Persistent oxidative stress in colorectal carcinoma patients. Gackowski, D., Banaszkiewicz, Z., Rozalski, R., Jawien, A., Olinski, R. Int. J. Cancer (2002)
- Urinary thymine dimers and 8-oxo-2'-deoxyguanosine in psoriasis. Ahmad, J., Cooke, M.S., Hussieni, A., Evans, M.D., Patel, K., Burd, R.M., Bleiker, T.O., Hutchinson, P.E., Lunec, J. FEBS Lett. (1999)
- Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease. Nunomura, A., Chiba, S., Lippa, C.F., Cras, P., Kalaria, R.N., Takeda, A., Honda, K., Smith, M.A., Perry, G. Neurobiol. Dis. (2004)
- Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies. Nunomura, A., Chiba, S., Kosaka, K., Takeda, A., Castellani, R.J., Smith, M.A., Perry, G. Neuroreport (2002)
- Increased oxidative DNA damage in mammary tumor cells by continuous epidermal growth factor stimulation. Hamada, J., Nakata, D., Nakae, D., Kobayashi, Y., Akai, H., Konishi, Y., Okada, F., Shibata, T., Hosokawa, M., Moriuchi, T. J. Natl. Cancer Inst. (2001)
- Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Brieba, L.G., Eichman, B.F., Kokoska, R.J., Doublié, S., Kunkel, T.A., Ellenberger, T. EMBO J. (2004)
- DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine. Helbock, H.J., Beckman, K.B., Shigenaga, M.K., Walter, P.B., Woodall, A.A., Yeo, H.C., Ames, B.N. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid. Suh, J.H., Shigeno, E.T., Morrow, J.D., Cox, B., Rocha, A.E., Frei, B., Hagen, T.M. FASEB J. (2001)
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- Base pair stability of 8-chloro- and 8-iodo-2'-deoxyguanosine opposite 2'-deoxycytidine: implications regarding the bioactivity of 8-oxo-2'-deoxyguanosine. Hamm, M.L., Rajguru, S., Downs, A.M., Cholera, R. J. Am. Chem. Soc. (2005)
- A novel assay of 8-oxo-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) activity in cultured cells and its use for evaluation of cadmium(II) inhibition of this activity. Bialkowski, K., Kasprzak, K.S. Nucleic Acids Res. (1998)
- Oxidative damage in tissues of rats exposed to cigarette smoke. Park, E.M., Park, Y.M., Gwak, Y.S. Free Radic. Biol. Med. (1998)
- Activity of the antimutagenic enzyme 8-oxo-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) in cultured chinese hamster ovary cells: effects of cell cycle, proliferation rate, and population density. Bialkowski, K., Kasprzak, K.S. Free Radic. Biol. Med. (2000)
- Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Zhang, J., Perry, G., Smith, M.A., Robertson, D., Olson, S.J., Graham, D.G., Montine, T.J. Am. J. Pathol. (1999)
- Two pathways for chromium(VI)-induced DNA damage in 14 day chick embryos: Cr-DNA binding in liver and 8-oxo-2'-deoxyguanosine in red blood cells. Misra, M., Alcedo, J.A., Wetterhahn, K.E. Carcinogenesis (1994)
- An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress. Yoshimura, D., Sakumi, K., Ohno, M., Sakai, Y., Furuichi, M., Iwai, S., Nakabeppu, Y. J. Biol. Chem. (2003)
- Redox ribonucleosides. Isolation and characterization of 5-hydroxyuridine, 8-hydroxyguanosine, and 8-hydroxyadenosine from Torula yeast RNA. Yanagawa, H., Ogawa, Y., Ueno, M. J. Biol. Chem. (1992)
- Measurement of 8-oxo-2'-deoxyguanosine and 8-oxo-2'-deoxyadenosine in DNA and human urine by high performance liquid chromatography-electrospray tandem mass spectrometry. Weimann, A., Belling, D., Poulsen, H.E. Free Radic. Biol. Med. (2001)
- N2-methyl-8-oxoguanine: a tRNA urinary metabolite--role of xanthine oxidase. Helbock, H.J., Thompson, J., Yeo, H., Ames, B.N. Free Radic. Biol. Med. (1996)
- Involvement of superoxide in excitotoxicity and DNA fragmentation in striatal vulnerability in mice after treatment with the mitochondrial toxin, 3-nitropropionic acid. Kim, G.W., Chan, P.H. J. Cereb. Blood Flow Metab. (2002)
- Expression of 8-oxoguanine DNA glycosylase (OGG1) in Parkinson's disease and related neurodegenerative disorders. Fukae, J., Takanashi, M., Kubo, S., Nishioka, K., Nakabeppu, Y., Mori, H., Mizuno, Y., Hattori, N. Acta Neuropathol. (2005)
- Phospho-eNOS Ser-114 in human mesenchymal stem cells: constitutive phosphorylation, nuclear localization and upregulation during mitosis. Klinz, F.J., Schmidt, A., Schinköthe, T., Arnhold, S., Desai, B., Popken, F., Brixius, K., Schwinger, R., Mehlhorn, U., Staib, P., Addicks, K., Bloch, W. Eur. J. Cell Biol. (2005)
- Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome. Nunomura, A., Perry, G., Pappolla, M.A., Friedland, R.P., Hirai, K., Chiba, S., Smith, M.A. J. Neuropathol. Exp. Neurol. (2000)
- Oxidative damage is the earliest event in Alzheimer disease. Nunomura, A., Perry, G., Aliev, G., Hirai, K., Takeda, A., Balraj, E.K., Jones, P.K., Ghanbari, H., Wataya, T., Shimohama, S., Chiba, S., Atwood, C.S., Petersen, R.B., Smith, M.A. J. Neuropathol. Exp. Neurol. (2001)
- In vitro evolution of the hammerhead ribozyme to a purine-specific ribozyme using mutagenic PCR with two nucleotide analogues. Kore, A.R., Vaish, N.K., Morris, J.A., Eckstein, F. J. Mol. Biol. (2000)
- Modulation of hOGG1 DNA repair enzyme in human cultured cells in response to pro-oxidant and antioxidant challenge. Mistry, P., Herbert, K.E. Free Radic. Biol. Med. (2003)
- Time-course of mitochondrial gene expressions in mice brains: implications for mitochondrial dysfunction, oxidative damage, and cytochrome c in aging. Manczak, M., Jung, Y., Park, B.S., Partovi, D., Reddy, P.H. J. Neurochem. (2005)
- Studies on genotoxic effects of iron overload and alcohol in an animal model of hepatocarcinogenesis. Stål, P., Olsson, J., Svoboda, P., Hultcrantz, R., Harms-Ringdahl, M., Eriksson, L.C. J. Hepatol. (1997)