The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Demofix     1-[2-[(7-chlorobenzothiophen- 3-yl)methoxy]...

Synonyms: Sertaconazol, Sertaconazole, Sertaconazolum, SureCN66043, CHEMBL1201196, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Sertaconazole nitrate


High impact information on Sertaconazole nitrate


Chemical compound and disease context of Sertaconazole nitrate


Biological context of Sertaconazole nitrate


Anatomical context of Sertaconazole nitrate


Associations of Sertaconazole nitrate with other chemical compounds


Gene context of Sertaconazole nitrate

  • The activity of 7-chloro-3-[1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl) ethoxy-methyl]benzo[b]thiophene (sertaconazole, FI-7045, CAS 99592-32,2) was studied in a randomized parallel double-blind clinical trial on 21 patients suffering from Pityriasis versicolor (confirmed by KOH microscopic examination and exploration with Wood's light) [20].
  • The acute toxicity of 7-chloro-3-[1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy- methyl]benzo[b]thiophene (sertaconazole, FI-7045, CAS 99592-32-2) was evaluated in mice and rats after single administration by oral, subcutaneous and intraperitoneal routes [21].

Analytical, diagnostic and therapeutic context of Sertaconazole nitrate


  1. Sertaconazole in the treatment of pediatric patients with cutaneous dermatophyte infections. Van Esso, D., Fajo, G., Losada, I., Vilallonga, M., Casanovas, J.M., Clanxet, J., Aliaga, A. Clinical therapeutics. (1995) [Pubmed]
  2. Review of in vitro activity of sertaconazole nitrate in the treatment of superficial fungal infections. Pfaller, M.A., Sutton, D.A. Diagn. Microbiol. Infect. Dis. (2006) [Pubmed]
  3. Anti-inflammatory and anti-itch activity of sertaconazole nitrate. Liebel, F., Lyte, P., Garay, M., Babad, J., Southall, M.D. Arch. Dermatol. Res. (2006) [Pubmed]
  4. In vivo activity of sertaconazole in experimental candidiasis in the mouse. Palacin, C., Sacristán, A., Ortiz, J.A. Drugs under experimental and clinical research. (1990) [Pubmed]
  5. In-vitro antifungal activity of sertaconazole, bifonazole, ketoconazole, and miconazole against yeasts of the Candida genus. Carrilo-Muñoz, A.J., Tur, C., Torres, J. J. Antimicrob. Chemother. (1996) [Pubmed]
  6. Single-dose sertaconazole vaginal tablet treatment of vulvovaginal candidiasis. Wang, P.H., Chao, H.T., Chen, C.L., Yuan, C.C. Journal of the Chinese Medical Association : JCMA. (2006) [Pubmed]
  7. Nail penetration of sertaconazole with a sertaconazole-containing nail patch formulation. Susilo, R., Korting, H.C., Greb, W., Strauss, U.P. American journal of clinical dermatology. (2006) [Pubmed]
  8. Multi-centre double-blind trial on the efficacy and safety of sertaconazole 2% cream in comparison with miconazole 2% cream on patients suffering from cutaneous mycoses. Alomar, C., Bassas, S., Casas, M., Crespo, V., Ferrándiz, C., Fonseca, E., Hernández, B., Noguera, J., Pedragosa, R., Peyrí, J. Arzneimittel-Forschung. (1992) [Pubmed]
  9. Chronic toxicity studies of sertaconazole after oral administration to rats and ferrets. Romero, A., Villamayor, F., Grau, M.T., Sacristán, A., Ortiz, J.A. Arzneimittel-Forschung. (1992) [Pubmed]
  10. Sertaconazole in the treatment of mycoses: from dermatology to gynecology. Torres, J., Márquez, M., Camps, F. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. (2000) [Pubmed]
  11. Sertaconazole: updated review of a topical antifungal agent. Carrillo-Muñoz, A.J., Giusiano, G., Ezkurra, P.A., Quindós, G. Expert review of anti-infective therapy. (2005) [Pubmed]
  12. Reproduction toxicity of sertaconazole. Segment II (teratology) and Segment III (peri-postnatal toxicity). Romero, A., Grau, M.T., Villamayor, F., Sacristán, A., Ortiz, J.A. Arzneimittel-Forschung. (1992) [Pubmed]
  13. Ocular tolerance of sertaconazole gel. Romero, A., Grau, M.T., Villamayor, F., Zapatero, J., Mayordomo, L., Tortajada, A., Sacristán, A., Ortiz, J.A. Mycoses (1996) [Pubmed]
  14. Antiinflammatory activity of topically applied sertaconazole nitrate. Agut, J., Tarrida, N., Sacristán, A., Ortiz, J.A. Methods and findings in experimental and clinical pharmacology. (1996) [Pubmed]
  15. In-vitro antifungal activity of sertaconazole, econazole, and bifonazole against Candida spp. Carrillo-Muñoz, A.J., Torres-Rodriguez, J.M. J. Antimicrob. Chemother. (1995) [Pubmed]
  16. In vitro activity of sertaconazole against dermatophyte isolates with reduced fluconazole susceptibility. Carrillo-Muñoz, A.J., Fernández-Torres, B., Cárdenes, D.C., Guarro, J. Chemotherapy. (2003) [Pubmed]
  17. Determination of sertaconazole nitrate, a new imidazole antifungal, by high-performance liquid chromatography. Albet, C., Fernandez, J.M., Rozman, E., Perez, J.A., Sacristan, A., Ortiz, J.A. Journal of pharmaceutical and biomedical analysis. (1992) [Pubmed]
  18. Comparative study of antifungal activity of sertaconazole, terbinafine, and bifonazole against clinical isolates of Candida spp., Cryptococcus neoformans and dermatophytes. Carillo-Muñoz, A.J., Tur-Tur, C. Chemotherapy. (1997) [Pubmed]
  19. Comparative study of the in vitro antifungal activity of bifonazole, naftifine and sertaconazole against yeasts. Carrillo-Muñoz, A.J., Tur-Tur, C., Bornay-Llinares, F.J., Arévalo, P. Journal of chemotherapy (Florence, Italy) (1999) [Pubmed]
  20. Therapeutic efficacy and safety of the new antimycotic sertaconazole in the treatment of Pityriasis versicolor. Nasarre, J., Umbert, P., Herrero, E., Roset, P., Márquez, M., Torres, J., Ortiz, J.A. Arzneimittel-Forschung. (1992) [Pubmed]
  21. Acute toxicity studies of sertaconazole. Grau, M.T., Romero, A., Sacristán, A., Ortiz, J.A. Arzneimittel-Forschung. (1992) [Pubmed]
  22. Sertaconazole/hydroxypropyl-beta-cyclodextrin complexation: isothermal titration calorimetry and solubility approaches. Rodriguez-Perez, A.I., Rodriguez-Tenreiro, C., Alvarez-Lorenzo, C., Taboada, P., Concheiro, A., Torres-Labandeira, J.J. Journal of pharmaceutical sciences. (2006) [Pubmed]
WikiGenes - Universities