Disease relevance of Ir1

• Immune response to cholera toxin epitope inserted in Salmonella flagellin [1].
• Immune response to hepatitis B surface antigen: enhancement by prior injection of antibodies to the idiotype [2].
• Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression [3].
• Immune response to inactivated syngeneic mammary adenocarcinoma cells. II. Parameters of immunogenicity in DBA/2 mice [4].
• Immune response in overnutrition [5].

High impact information on Ir1

• Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice [6].
• Immune response genes of the murine major histocompatibility complex encode cell-surface glycoproteins that are expressed predominantly on B cells and macrophages and regulate immune responsiveness by restricting antigen recognition by T cells [7].
• Immune response (Ir) genes expressed at macrophage-B lymphocyte interactions [8].
• Immune response in mice that lack the interferon-gamma receptor [9].
• Immune response in Stat2 knockout mice [10].

Chemical compound and disease context of Ir1

• Immunization of mice with lipopeptides bypasses the prerequisite for adjuvant. Immune response of BALB/c mice to human immunodeficiency virus envelope glycoprotein [11].
• Complement C1q and C3 Are Critical for the Innate Immune Response to Streptococcus pneumoniae in the Central Nervous System [12].
• The SecA2 Secretion Factor of Mycobacterium tuberculosis Promotes Growth in Macrophages and Inhibits the Host Immune Response [13].
• 1. Immune response-modulating drugs such as thalidomide may be of therapeutic value in the treatment of chronic inflammatory bowel diseases including Crohn's disease (CD) [14].
• The presentations were as follows: (1) Effects of Ethanol on Immune Response to Hepatitis C Virus by Jack R [15].

Biological context of Ir1

• Cellular and genetic control of antibody responses in vitro. III. Immune response gene regulation of accessory cell function [16].
• Immune response to a differentiation antigen induced by altered antigen: a study of tumor rejection and autoimmunity [17].
• Immune response to progressor variants derived from transfection of an ultraviolet radiation-induced C3H mouse regressor tumor cell line with activated Harvey-ras oncogene [18].
• Immune response to levan. I. Kinetics and ontogeny of anti-levan and anti-inulin antibody response and of expression of cross-reactive idiotype [19].
• Immune response to the p-azobenzenearsonate (ABA)-GAT conjugate. II. Hapten-specific T cells induced with ABA-GAT in GAT responder X nonresponder F1 hybrids are restricted to the nonresponder haplotype [20].

Anatomical context of Ir1

• Immune response gene function correlates with the expression of an Ia antigen. II. A quantitative deficiency in Ae:E alpha complex expression causes a corresponding defect in antigen-presenting cell function [21].
• Immune response genes control T killer cell response against Moloney tumor antigen cytolysis regulating reactions against the best available H-2 + viral antigen association [22].
• Immune response to somatic cell hybrids between ultraviolet radiation-induced regressor and spontaneous progressor C3H mouse tumor cells [23].
• Immune response to phosphorylcholine. IX. Characterization of hybridoma anti-TEPC15 antibodies [24].
• Immune response to phosphorylcholine. VII. Functional evidence for three separate B cell subpopulations responding to TI and TD PC-antigens [25].

Associations of Ir1 with chemical compounds

• Immune response of BALB/c X DBA/2F1 mice to a tumor allograft during pyran copolymer-induced tumor enhancement [26].
• Immune response to phosphorylcholine. VIII. The response CBA/N mice to PC-LPS [27].
• Immune response against large tumors eradicated by treatment with cyclophosphamide and IL-12 [28].
• Immune response to alloantigens in vitro, amplification of the development of cytotoxic T lymphocytes by lipopolysaccharide and polyadenylic:polyuridylic acid [29].
• Immune response to the p-azobenzenearsonate (ABA)-GAT conjugate: role of I region genes in the selective activation of ABA-specific or GAT-specific T helper cells [30].

Other interactions of Ir1

• Immune response to incompatible alpha-gal epitopes on the graft was determined by transplanted-heart function and by production of anti-Gal after PKM immunizations [31].
• Immune response (Ir) gene(s) at the I-A subregion of the mouse H-2 complex influence susceptibility to experimental autoimmune myasthenia gravis (EAMG) [32].
• Immune response to Philadelphia chromosome-positive acute lymphoblastic leukemia induced by expression of CD80, interleukin 2, and granulocyte-macrophage colony-stimulating factor [33].
• Immune response in pigs vaccinated with plasmid DNA encoding ORF5 of porcine reproductive and respiratory syndrome virus [34].
• Immune response and airway reactivity in wild and IL-4 knockout mice exposed to latex allergens [35].

Analytical, diagnostic and therapeutic context of Ir1

• Immune response restored by gene therapy in mice [36].
• Immune response was determined by measuring the levels of lavage cytokines and serum antibodies [37].
• Immune response, accommodation, and tolerance to transplantation carbohydrate antigens [38].
• Immune response to atypical mycobacteria: immunocompetence of heavily infected mice measured in vivo fails to substantiate immunosuppression data obtained in vitro [39].
• Biodegradable microspheres II: Immune response to a heterologous and an autologous protein entrapped in polyacryl starch microparticles [40].

References