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Gene Review

Ir1  -  immune response 1

Mus musculus

Synonyms: Ir-1
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Analytical, diagnostic and therapeutic context of Ir1


  1. Immune response to cholera toxin epitope inserted in Salmonella flagellin. Newton, S.M., Jacob, C.O., Stocker, B.A. Science (1989) [Pubmed]
  2. Immune response to hepatitis B surface antigen: enhancement by prior injection of antibodies to the idiotype. Kennedy, R.C., Adler-Storthz, K., Henkel, R.D., Sanchez, Y., Melnick, J.L., Dreesman, G.R. Science (1983) [Pubmed]
  3. Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression. Fung-Leung, W.P., Kündig, T.M., Zinkernagel, R.M., Mak, T.W. J. Exp. Med. (1991) [Pubmed]
  4. Immune response to inactivated syngeneic mammary adenocarcinoma cells. II. Parameters of immunogenicity in DBA/2 mice. DeLustro, F., Haskill, J.S. J. Natl. Cancer Inst. (1980) [Pubmed]
  5. Immune response in overnutrition. Chandra, R.K. Cancer Res. (1981) [Pubmed]
  6. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Tisch, R., Yang, X.D., Singer, S.M., Liblau, R.S., Fugger, L., McDevitt, H.O. Nature (1993) [Pubmed]
  7. Nucleotide sequence of mutant I-A beta bm12 gene is evidence for genetic exchange between mouse immune response genes. McIntyre, K.R., Seidman, J.G. Nature (1984) [Pubmed]
  8. Immune response (Ir) genes expressed at macrophage-B lymphocyte interactions. Howie, S., Feldmann, M. Nature (1978) [Pubmed]
  9. Immune response in mice that lack the interferon-gamma receptor. Huang, S., Hendriks, W., Althage, A., Hemmi, S., Bluethmann, H., Kamijo, R., Vilcek, J., Zinkernagel, R.M., Aguet, M. Science (1993) [Pubmed]
  10. Immune response in Stat2 knockout mice. Park, C., Li, S., Cha, E., Schindler, C. Immunity (2000) [Pubmed]
  11. Immunization of mice with lipopeptides bypasses the prerequisite for adjuvant. Immune response of BALB/c mice to human immunodeficiency virus envelope glycoprotein. Martinon, F., Gras-Masse, H., Boutillon, C., Chirat, F., Deprez, B., Guillet, J.G., Gomard, E., Tartar, A., Levy, J.P. J. Immunol. (1992) [Pubmed]
  12. Complement C1q and C3 Are Critical for the Innate Immune Response to Streptococcus pneumoniae in the Central Nervous System. Rupprecht, T.A., Angele, B., Klein, M., Heesemann, J., Pfister, H.W., Botto, M., Koedel, U. J. Immunol. (2007) [Pubmed]
  13. The SecA2 Secretion Factor of Mycobacterium tuberculosis Promotes Growth in Macrophages and Inhibits the Host Immune Response. Kurtz, S., McKinnon, K.P., Runge, M.S., Ting, J.P., Braunstein, M. Infect. Immun. (2006) [Pubmed]
  14. Thalidomide impairment of trinitrobenzene sulphonic acid-induced colitis in the rat - role of endothelial cell-leukocyte interaction. Lienenlüke, B., Stojanovic, T., Fiebig, T., Fayyazi, A., Germann, T., Hecker, M. Br. J. Pharmacol. (2001) [Pubmed]
  15. Acute and chronic alcohol abuse modulate immunity. Brown, L.A., Cook, R.T., Jerrells, T.R., Kolls, J.K., Nagy, L.E., Szabo, G., Wands, J.R., Kovacs, E.J. Alcohol. Clin. Exp. Res. (2006) [Pubmed]
  16. Cellular and genetic control of antibody responses in vitro. III. Immune response gene regulation of accessory cell function. Singer, A., Cowing, C., Hathcock, K.S., Dickler, H.B., Hodes, R.J. J. Exp. Med. (1978) [Pubmed]
  17. Immune response to a differentiation antigen induced by altered antigen: a study of tumor rejection and autoimmunity. Naftzger, C., Takechi, Y., Kohda, H., Hara, I., Vijayasaradhi, S., Houghton, A.N. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  18. Immune response to progressor variants derived from transfection of an ultraviolet radiation-induced C3H mouse regressor tumor cell line with activated Harvey-ras oncogene. Kaba, D.S., Pierceall, W.E., Price, J.E., Ananthaswamy, H.N. Cancer Res. (1990) [Pubmed]
  19. Immune response to levan. I. Kinetics and ontogeny of anti-levan and anti-inulin antibody response and of expression of cross-reactive idiotype. Bona, C., Lieberman, R., Chien, C.C., Mond, J., House, S., Green, I., Paul, W.E. J. Immunol. (1978) [Pubmed]
  20. Immune response to the p-azobenzenearsonate (ABA)-GAT conjugate. II. Hapten-specific T cells induced with ABA-GAT in GAT responder X nonresponder F1 hybrids are restricted to the nonresponder haplotype. Regnier, D., Seman, M. J. Immunol. (1983) [Pubmed]
  21. Immune response gene function correlates with the expression of an Ia antigen. II. A quantitative deficiency in Ae:E alpha complex expression causes a corresponding defect in antigen-presenting cell function. Matis, L.A., Jones, P.P., Murphy, D.B., Hedrick, S.M., Lerner, E.A., Janeway, C.A., McNicholas, J.M., Schwartz, R.H. J. Exp. Med. (1982) [Pubmed]
  22. Immune response genes control T killer cell response against Moloney tumor antigen cytolysis regulating reactions against the best available H-2 + viral antigen association. Gomard, E., Hénin, Y., Colombani, M.J., Lévy, J.P. J. Exp. Med. (1980) [Pubmed]
  23. Immune response to somatic cell hybrids between ultraviolet radiation-induced regressor and spontaneous progressor C3H mouse tumor cells. Chen, P.W., Kaba, D.S., Ananthaswamy, H.N. Cancer Res. (1990) [Pubmed]
  24. Immune response to phosphorylcholine. IX. Characterization of hybridoma anti-TEPC15 antibodies. Wittner, M.K., Bach, M.A., Köhler, H. J. Immunol. (1982) [Pubmed]
  25. Immune response to phosphorylcholine. VII. Functional evidence for three separate B cell subpopulations responding to TI and TD PC-antigens. Fung, J., Köhler, H. J. Immunol. (1980) [Pubmed]
  26. Immune response of BALB/c X DBA/2F1 mice to a tumor allograft during pyran copolymer-induced tumor enhancement. Schultz, R.M., Woods, W.A., Mohr, S.J., Chirigos, M.A. Cancer Res. (1976) [Pubmed]
  27. Immune response to phosphorylcholine. VIII. The response CBA/N mice to PC-LPS. Köhler, H., Smyk, S., Fung, J. J. Immunol. (1981) [Pubmed]
  28. Immune response against large tumors eradicated by treatment with cyclophosphamide and IL-12. Tsung, K., Meko, J.B., Tsung, Y.L., Peplinski, G.R., Norton, J.A. J. Immunol. (1998) [Pubmed]
  29. Immune response to alloantigens in vitro, amplification of the development of cytotoxic T lymphocytes by lipopolysaccharide and polyadenylic:polyuridylic acid. Narayanan, P.R., Kloehn, D.B., Sundharadas, G. J. Immunol. (1978) [Pubmed]
  30. Immune response to the p-azobenzenearsonate (ABA)-GAT conjugate: role of I region genes in the selective activation of ABA-specific or GAT-specific T helper cells. Seman, M., Regnier, D., Hermier, B., Dubert, J.M. J. Immunol. (1982) [Pubmed]
  31. Mouse-heart grafts expressing an incompatible carbohydrate antigen. II. Transition from accommodation to tolerance. Ogawa, H., Mohiuddin, M.M., Yin, D.P., Shen, J., Chong, A.S., Galili, U. Transplantation (2004) [Pubmed]
  32. Mutation at I-A beta chain prevents experimental autoimmune myasthenia gravis. Christadoss, P., Lindstrom, J.M., Melvold, R.W., Talal, N. Immunogenetics (1985) [Pubmed]
  33. Immune response to Philadelphia chromosome-positive acute lymphoblastic leukemia induced by expression of CD80, interleukin 2, and granulocyte-macrophage colony-stimulating factor. Stripecke, R., Skelton, D.C., Gruber, T., Afar, D., Pattengale, P.K., Witte, O.N., Kohn, D.B. Hum. Gene Ther. (1998) [Pubmed]
  34. Immune response in pigs vaccinated with plasmid DNA encoding ORF5 of porcine reproductive and respiratory syndrome virus. Pirzadeh, B., Dea, S. J. Gen. Virol. (1998) [Pubmed]
  35. Immune response and airway reactivity in wild and IL-4 knockout mice exposed to latex allergens. Xia, J.Q., Rickaby, D.A., Kelly, K.J., Choi, H., Dawson, C.A., Kurup, V.P. Int. Arch. Allergy Immunol. (1999) [Pubmed]
  36. Immune response restored by gene therapy in mice. Steinmetz, M. Nature (1985) [Pubmed]
  37. An antigen-independent but not antigen-specific T(H)1 response provides protection in the murine airway inflammation model. Burger, M.S., Zuleger, C.L., Chu, Q., Gao, X., Payne, L.G., Chen, D. J. Allergy Clin. Immunol. (2004) [Pubmed]
  38. Immune response, accommodation, and tolerance to transplantation carbohydrate antigens. Galili, U. Transplantation (2004) [Pubmed]
  39. Immune response to atypical mycobacteria: immunocompetence of heavily infected mice measured in vivo fails to substantiate immunosuppression data obtained in vitro. Orme, I.M., Collins, F.M. Infect. Immun. (1984) [Pubmed]
  40. Biodegradable microspheres II: Immune response to a heterologous and an autologous protein entrapped in polyacryl starch microparticles. Artursson, P., Edman, P., Sjöholm, I. J. Pharmacol. Exp. Ther. (1985) [Pubmed]
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