Gene Review:
C3 - complement component 3
Mus musculus
Synonyms:
AI255234, ASP, Complement C3, HSE-MSF, Plp, ...
- Complement C4 is protective for lupus disease independent of C3. Einav, S., Pozdnyakova, O.O., Ma, M., Carroll, M.C. J. Immunol. (2002)
- Distinct tissue site-specific requirements of mast cells and complement components C3/C5a receptor in IgG immune complex-induced injury of skin and lung. Baumann, U., Chouchakova, N., Gewecke, B., Köhl, J., Carroll, M.C., Schmidt, R.E., Gessner, J.E. J. Immunol. (2001)
- The alternative activation pathway and complement component C3 are critical for a protective immune response against Pseudomonas aeruginosa in a murine model of pneumonia. Mueller-Ortiz, S.L., Drouin, S.M., Wetsel, R.A. Infect. Immun. (2004)
- Lack of complement factor C3, but not factor B, increases hyperlipidemia and atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/- mice. Persson, L., Borén, J., Robertson, A.K., Wallenius, V., Hansson, G.K., Pekna, M. Arterioscler. Thromb. Vasc. Biol. (2004)
- Expression of polypeptide segments of the human complement component C3 in E. coli: genetic and immunological characterization of cDNA clones specific for the alpha-chain of C3. Ma, D., Sessler, M.J., Meyer, T.F., Schrod, L., Hänsch, G.M., Burger, R. J. Immunol. (1985)
- Synthetic Alzheimer amyloid beta/A4 peptides enhance production of complement C3 component by cultured microglial cells. Haga, S., Ikeda, K., Sato, M., Ishii, T. Brain Res. (1993)
- A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q. Kang, Y.S., Do, Y., Lee, H.K., Park, S.H., Cheong, C., Lynch, R.M., Loeffler, J.M., Steinman, R.M., Park, C.G. Cell (2006)
- Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H. Pickering, M.C., Cook, H.T., Warren, J., Bygrave, A.E., Moss, J., Walport, M.J., Botto, M. Nat. Genet. (2002)
- Local extrahepatic expression of complement genes C3, factor B, C2, and C4 is increased in murine lupus nephritis. Passwell, J., Schreiner, G.F., Nonaka, M., Beuscher, H.U., Colten, H.R. J. Clin. Invest. (1988)
- Cutting edge: the absence of C3 demonstrates a role for complement in Th2 effector functions in a murine model of pulmonary allergy. Drouin, S.M., Corry, D.B., Kildsgaard, J., Wetsel, R.A. J. Immunol. (2001)
- Cellular specificity of murine renal C3 expression in two models of inflammation. Ault, B.H., Colten, H.R. Immunology (1994)
- Synergistic effect of romurtide with ampicillin against pneumococcal pneumonia in mice. Nakajima, R., Namba, K., Ishida, Y., Katsuma, E., Otani, T., Osada, Y. Chemotherapy. (1992)
- The proinflammatory mediators C3a and C5a are essential for liver regeneration. Strey, C.W., Markiewski, M., Mastellos, D., Tudoran, R., Spruce, L.A., Greenbaum, L.E., Lambris, J.D. J. Exp. Med. (2003)
- Interleukin 6 influences germinal center development and antibody production via a contribution of C3 complement component. Kopf, M., Herren, S., Wiles, M.V., Pepys, M.B., Kosco-Vilbois, M.H. J. Exp. Med. (1998)
- C1q governs deposition of circulating immune complexes and leukocyte Fcgamma receptors mediate subsequent neutrophil recruitment. Stokol, T., O'Donnell, P., Xiao, L., Knight, S., Stavrakis, G., Botto, M., von Andrian, U.H., Mayadas, T.N. J. Exp. Med. (2004)
- Acylation-stimulating protein (ASP) deficiency induces obesity resistance and increased energy expenditure in ob/ob mice. Xia, Z., Sniderman, A.D., Cianflone, K. J. Biol. Chem. (2002)
- Reduced body weight, adipose tissue, and leptin levels despite increased energy intake in female mice lacking acylation-stimulating protein. Murray, I., Havel, P.J., Sniderman, A.D., Cianflone, K. Endocrinology (2000)
- Ovarian steroid-regulated synthesis and secretion of complement C3 and factor B in mouse endometrium during the natural estrous cycle and pregnancy period. Li, S.H., Huang, H.L., Chen, Y.H. Biol. Reprod. (2002)
- Increased levels of acylation-stimulating protein in interleukin-6-deficient (IL-6(-/-)) mice. Wernstedt, I., Olsson, B., Jernås, M., Paglialunga, S., Carlsson, L.M., Smith, U., Cianflone, K., Wallenius, K., Wallenius, V. Endocrinology (2006)
- Detection and quantification of the control proteins of the alternative pathway of complement in 3T3-L1 adipocytes. Peake, P.W., O'Grady, S., Pussell, B.A., Charlesworth, J.A. Eur. J. Clin. Invest. (1997)
- Cis- and trans-acting elements required for constitutive and cytokine-regulated expression of the mouse complement C3 gene. Kawamura, N., Singer, L., Wetsel, R.A., Colten, H.R. Biochem. J. (1992)
- Complement-mediated clearance of erythrocytes: mechanism and delineation of the regulatory roles of Crry and DAF. Decay-accelerating factor. Molina, H., Miwa, T., Zhou, L., Hilliard, B., Mastellos, D., Maldonado, M.A., Lambris, J.D., Song, W.C. Blood (2002)
- Failure to induce anti-glomerular basement membrane glomerulonephritis in TNF alpha/beta deficient mice. Ryffel, B., Eugster, H., Haas, C., Le Hir, M. International journal of experimental pathology. (1998)
- Extent of the mouse t complex and its inversions shown by in situ hybridization. Lyon, M.F., Zenthon, J., Evans, E.P., Burtenshaw, M.D., Willison, K.R. Immunogenetics (1988)
- The embryotrophic activity of oviductal cell-derived complement C3b and iC3b, a novel function of complement protein in reproduction. Lee, Y.L., Lee, K.F., Xu, J.S., He, Q.Y., Chiu, J.F., Lee, W.M., Luk, J.M., Yeung, W.S. J. Biol. Chem. (2004)
- Weight gain in relation to plasma levels of complement factor 3: results from a population-based cohort study. Engström, G., Hedblad, B., Janzon, L., Lindgärde, F. Diabetologia (2005)