Gene Review:
Dcx - doublecortin
Mus musculus
Synonyms:
Dbct, Dcn, Doublin, Lis-X, Lissencephalin-X, ...
- Mutational and expression analysis of the reelin pathway components CDK5 and doublecortin in gangliogliomas. Becker, A.J., Klein, H., Baden, T., Aigner, L., Normann, S., Elger, C.E., Schramm, J., Wiestler, O.D., Blümcke, I. Acta Neuropathol. (2002)
- Ectopic doublecortin gene expression suppresses the malignant phenotype in glioblastoma cells. Santra, M., Zhang, X., Santra, S., Jiang, F., Chopp, M. Cancer Res. (2006)
- Neuronal nitric oxide synthase and ischemia-induced neurogenesis. Sun, Y., Jin, K., Childs, J.T., Xie, L., Mao, X.O., Greenberg, D.A. J. Cereb. Blood Flow Metab. (2005)
- Doublecortin is preferentially expressed in invasive human brain tumors. Daou, M.C., Smith, T.W., Litofsky, N.S., Hsieh, C.C., Ross, A.H. Acta Neuropathol. (2005)
- Doublecortin maintains bipolar shape and nuclear translocation during migration in the adult forebrain. Koizumi, H., Higginbotham, H., Poon, T., Tanaka, T., Brinkman, B.C., Gleeson, J.G. Nat. Neurosci. (2006)
- Genetic interactions between doublecortin and doublecortin-like kinase in neuronal migration and axon outgrowth. Deuel, T.A., Liu, J.S., Corbo, J.C., Yoo, S.Y., Rorke-Adams, L.B., Walsh, C.A. Neuron (2006)
- Doublecortin-like kinase controls neurogenesis by regulating mitotic spindles and M phase progression. Shu, T., Tseng, H.C., Sapir, T., Stern, P., Zhou, Y., Sanada, K., Fischer, A., Coquelle, F.M., Reiner, O., Tsai, L.H. Neuron (2006)
- Ectopic expression of doublecortin protects adult rat progenitor cells and human glioma cells from severe oxygen and glucose deprivation. Santra, M., Liu, X.S., Santra, S., Zhang, J., Zhang, R.L., Zhang, Z.G., Chopp, M. Neuroscience (2006)
- Cdk5 phosphorylation of doublecortin ser297 regulates its effect on neuronal migration. Tanaka, T., Serneo, F.F., Tseng, H.C., Kulkarni, A.B., Tsai, L.H., Gleeson, J.G. Neuron (2004)
- Identification of neurabin II as a novel doublecortin interacting protein. Tsukada, M., Prokscha, A., Oldekamp, J., Eichele, G. Mech. Dev. (2003)
- Doublecortin association with actin filaments is regulated by neurabin II. Tsukada, M., Prokscha, A., Ungewickell, E., Eichele, G. J. Biol. Chem. (2005)
- Doublecortin interacts with mu subunits of clathrin adaptor complexes in the developing nervous system. Friocourt, G., Chafey, P., Billuart, P., Koulakoff, A., Vinet, M.C., Schaar, B.T., McConnell, S.K., Francis, F., Chelly, J. Mol. Cell. Neurosci. (2001)
- KIAA0369, doublecortin-like kinase, is expressed during brain development. Burgess, H.A., Martinez, S., Reiner, O. J. Neurosci. Res. (1999)
- Cloning and developmental expression of the murine homolog of doublecortin. Matsuo, N., Kawamoto, S., Matsubara, K., Okubo, K. Biochem. Biophys. Res. Commun. (1998)
- Transient calretinin expression defines early postmitotic step of neuronal differentiation in adult hippocampal neurogenesis of mice. Brandt, M.D., Jessberger, S., Steiner, B., Kronenberg, G., Reuter, K., Bick-Sander, A., von der Behrens, W., Kempermann, G. Mol. Cell. Neurosci. (2003)
- Reelin deficiency and displacement of mature neurons, but not neurogenesis, underlie the formation of granule cell dispersion in the epileptic hippocampus. Heinrich, C., Nitta, N., Flubacher, A., Müller, M., Fahrner, A., Kirsch, M., Freiman, T., Suzuki, F., Depaulis, A., Frotscher, M., Haas, C.A. J. Neurosci. (2006)
- Doublecortin, a stabilizer of microtubules. Horesh, D., Sapir, T., Francis, F., Wolf, S.G., Caspi, M., Elbaum, M., Chelly, J., Reiner, O. Hum. Mol. Genet. (1999)
- Impairment of dentate gyrus neuronal progenitor cell differentiation in a mouse model of temporal lobe epilepsy. Ledergerber, D., Fritschy, J.M., Kralic, J.E. Exp. Neurol. (2006)
- L-nitroimidazole ornithine limits exercise-induced increases in cell proliferation in the hippocampus of adult mice. Moon, M., Huh, Y., Park, C. Neuroreport (2006)
- Cleavage of doublecortin-like kinase by calpain releases an active kinase fragment from a microtubule anchorage domain. Burgess, H.A., Reiner, O. J. Biol. Chem. (2001)
- Multisite phosphorylation of doublecortin by cyclin-dependent kinase 5. Graham, M.E., Ruma-Haynes, P., Capes-Davis, A.G., Dunn, J.M., Tan, T.C., Valova, V.A., Robinson, P.J., Jeffrey, P.L. Biochem. J. (2004)
- Overexpression of MATH1 disrupts the coordination of neural differentiation in cerebellum development. Helms, A.W., Gowan, K., Abney, A., Savage, T., Johnson, J.E. Mol. Cell. Neurosci. (2001)
- Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons. Francis, F., Koulakoff, A., Boucher, D., Chafey, P., Schaar, B., Vinet, M.C., Friocourt, G., McDonnell, N., Reiner, O., Kahn, A., McConnell, S.K., Berwald-Netter, Y., Denoulet, P., Chelly, J. Neuron (1999)
- Heterotopia formation in rat but not mouse neocortex after RNA interference knockdown of DCX. Ramos, R.L., Bai, J., LoTurco, J.J. Cereb. Cortex (2006)
- Magnetic resonance imaging and histological studies of corpus callosal and hippocampal abnormalities linked to doublecortin deficiency. Kappeler, C., Dhenain, M., Phan Dinh Tuy, F., Saillour, Y., Marty, S., Fallet-Bianco, C., Souville, I., Souil, E., Pinard, J.M., Meyer, G., Encha-Razavi, F., Volk, A., Beldjord, C., Chelly, J., Francis, F. J. Comp. Neurol. (2007)
- Cerebral neurogenesis is induced by intranasal administration of growth factors. Jin, K., Xie, L., Childs, J., Sun, Y., Mao, X.O., Logvinova, A., Greenberg, D.A. Ann. Neurol. (2003)