Gene Review:
CPOX - coproporphyrinogen oxidase
Homo sapiens
Synonyms:
COX, CPO, CPX, Coprogen oxidase, Coproporphyrinogenase, ...
- Expression of coproporphyrinogen oxidase and synthesis of hemoglobin in human erythroleukemia K562 cells. Taketani, S., Furukawa, T., Furuyama, K. Eur. J. Biochem. (2001)
- Molecular characterization of porphyrias in Italy: a diagnostic flow-chart. Martinez di Montemuros, F., Di Pierro, E., Patti, E., Tavazzi, D., Danielli, M.G., Biolcati, G., Rocchi, E., Cappellini, M.D. Cell. Mol. Biol. (Noisy-le-grand) (2002)
- Mutant and wild-type alpha-synuclein interact with mitochondrial cytochrome C oxidase. Elkon, H., Don, J., Melamed, E., Ziv, I., Shirvan, A., Offen, D. J. Mol. Neurosci. (2002)
- Characterization and expression of cDNA encoding coproporphyrinogen oxidase from a patient with hereditary coproporphyria. Fujita, H., Kondo, M., Taketani, S., Nomura, N., Furuyama, K., Akagi, R., Nagai, T., Terajima, M., Galbraith, R.A., Sassa, S. Hum. Mol. Genet. (1994)
- A molecular defect in coproporphyrinogen oxidase gene causing harderoporphyria, a variant form of hereditary coproporphyria. Lamoril, J., Martasek, P., Deybach, J.C., Da Silva, V., Grandchamp, B., Nordmann, Y. Hum. Mol. Genet. (1995)
- Impaired motor imagery in right hemiparetic cerebral palsy. Mutsaarts, M., Steenbergen, B., Bekkering, H. Neuropsychologia (2007)
- Impact of pulmonary regurgitation and right ventricular dysfunction on oxygen uptake recovery kinetics in repaired tetralogy of Fallot. Giardini, A., Specchia, S., Coutsoumbas, G., Donti, A., Formigari, R., Fattori, R., Oppido, G., Gargiulo, G., Picchio, F.M. Eur. J. Heart Fail. (2006)
- Facial appearance and attachment in infants with orofacial clefts: a replication. Coy, K., Speltz, M.L., Jones, K. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association. (2002)
- Decreased activity of hepatic uroporphyrinogen decarboxylase in sporadic porphyria cutanea tarda. Elder, G.H., Lee, G.B., Tovey, J.A. N. Engl. J. Med. (1978)
- COX-3: just another COX or the solitary elusive target of paracetamol? Schwab, J.M., Schluesener, H.J., Laufer, S. Lancet (2003)
- Coproporphyrinogen-oxidase deficiency in hereditary coproporphyria. Nordmann, Y., Grandchamp, B., Phung, N., de Verneuil, H., Grelier, M., Neiré, J. Lancet (1977)
- The primary enzyme defect in hereditary coproporphyria. Elder, G.H., Evans, J.O., Thomas, N. Lancet (1976)
- Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia. Longley, M.J., Clark, S., Yu Wai Man, C., Hudson, G., Durham, S.E., Taylor, R.W., Nightingale, S., Turnbull, D.M., Copeland, W.C., Chinnery, P.F. Am. J. Hum. Genet. (2006)
- Homozygous hereditary coproporphyria caused by an arginine to tryptophane substitution in coproporphyrinogen oxidase and common intragenic polymorphisms. Martasek, P., Nordmann, Y., Grandchamp, B. Hum. Mol. Genet. (1994)
- Binding of copper is a mechanism of homocysteine toxicity leading to COX deficiency and apoptosis in primary neurons, PC12 and SHSY-5Y cells. Linnebank, M., Lutz, H., Jarre, E., Vielhaber, S., Noelker, C., Struys, E., Jakobs, C., Klockgether, T., Evert, B.O., Kunz, W.S., Wüllner, U. Neurobiol. Dis. (2006)
- 8-cyclopentyl-1,3-dipropylxanthine and other xanthines differentially bind to the wild-type and delta F508 first nucleotide binding fold (NBF-1) domains of the cystic fibrosis transmembrane conductance regulator. Cohen, B.E., Lee, G., Jacobson, K.A., Kim, Y.C., Huang, Z., Sorscher, E.J., Pollard, H.B. Biochemistry (1997)
- Activation of deltaF508 CFTR in a cystic fibrosis respiratory epithelial cell line by 4-phenylbutyrate, genistein and CPX. Andersson, C., Roomans, G.M. Eur. Respir. J. (2000)
- Outcome of subjects with idiopathic pulmonary fibrosis who fail corticosteroid therapy. Implications for further studies. Dayton, C.S., Schwartz, D.A., Helmers, R.A., Pueringer, R.J., Gilbert, S.R., Merchant, R.K., Hunninghake, G.W. Chest (1993)
- Modulation of penetrance by the wild-type allele in dominantly inherited erythropoietic protoporphyria and acute hepatic porphyrias. Gouya, L., Puy, H., Robreau, A.M., Lyoumi, S., Lamoril, J., Da Silva, V., Grandchamp, B., Deybach, J.C. Hum. Genet. (2004)
- Defects in cytochrome oxidase assembly in humans: lessons from yeast. Zee, J.M., Glerum, D.M. Biochem. Cell Biol. (2006)
- Kinetic evaluation of human cloned coproporphyrinogen oxidase using a ring isomer of the natural substrate. Cooper, C.L., Lash, T.D., Jones, M.A. Med. Sci. Monit. (2005)
- A novel frameshift mutation of the mtDNA COIII gene leads to impaired assembly of cytochrome c oxidase in a patient affected by Leigh-like syndrome. Tiranti, V., Corona, P., Greco, M., Taanman, J.W., Carrara, F., Lamantea, E., Nijtmans, L., Uziel, G., Zeviani, M. Hum. Mol. Genet. (2000)
- Mitochondrial (mt)DNA changes in tissue may not be reflected by depletion of mtDNA in peripheral blood mononuclear cells in HIV-infected patients. Maagaard, A., Holberg-Petersen, M., Kollberg, G., Oldfors, A., Sandvik, L., Bruun, J.N. Antivir. Ther. (Lond.) (2006)
- A pathogenic 15-base pair deletion in mitochondrial DNA-encoded cytochrome c oxidase subunit III results in the absence of functional cytochrome c oxidase. Hoffbuhr, K.C., Davidson, E., Filiano, B.A., Davidson, M., Kennaway, N.G., King, M.P. J. Biol. Chem. (2000)
- Ethanol withdrawal posttranslationally decreases the activity of cytochrome c oxidase in an estrogen reversible manner. Jung, M.E., Agarwal, R., Simpkins, J.W. Neurosci. Lett. (2007)
- Adherence modifies the regulation of gene expression induced by interleukin-10. Petit-Bertron, A.F., Pedron, T., Gross, U., Coppée, J.Y., Sansonetti, P.J., Cavaillon, J.M., Adib-Conquy, M. Cytokine (2005)
- Congenital erythropoietic porphyria: clinical, biochemical, and enzymatic profile of a severely affected infant. Huang, J.L., Zaider, E., Roth, P., Garcia, O., Pollack, S., Poh-Fitzpatrick, M.B. J. Am. Acad. Dermatol. (1996)
- Coexistence of hereditary coproporphyria and epilepsy: coproporphyrinogen oxidase deficiency in liver and kidney. Doss, M., von Tiepermann, R., Pflüger, K.H. J. Neurol. (1981)
- Human coproporphyrinogen oxidase is not a metalloprotein. Medlock, A.E., Dailey, H.A. J. Biol. Chem. (1996)
- Hereditary coproporphyria: exon screening by heteroduplex analysis detects three novel mutations in the coproporphyrinogen oxidase gene. Schreiber, W.E., Zhang, X., Senz, J., Jamani, A. Hum. Mutat. (1997)
- Epolones induce erythropoietin expression via hypoxia-inducible factor-1 alpha activation. Wanner, R.M., Spielmann, P., Stroka, D.M., Camenisch, G., Camenisch, I., Scheid, A., Houck, D.R., Bauer, C., Gassmann, M., Wenger, R.H. Blood (2000)