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Gene Review

env  -  protein-coding

Human T-lymphotropic virus 1

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Disease relevance of env


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Biological context of env


Anatomical context of env


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Analytical, diagnostic and therapeutic context of env


  1. New insights in HTLV-I phylogeny by sequencing and analyzing the entire envelope gene. Capdepont, S., Londos-Gagliardi, D., Joubert, M., Correze, P., Lafon, M.E., Guillemain, B., Fleury, H.J. AIDS Res. Hum. Retroviruses (2005) [Pubmed]
  2. Recognition of human T cell leukemia virus type I (HTLV-I) gag and pX gene products by MHC-restricted cytotoxic T lymphocytes induced in rats against syngeneic HTLV-I-infected cells. Tanaka, Y., Tozawa, H., Koyanagi, Y., Shida, H. J. Immunol. (1990) [Pubmed]
  3. Priming for in vitro and in vivo anti-human T lymphotropic virus type 1 cellular immunity by virus-related protein reconstituted into liposome. Noguchi, Y., Noguchi, T., Sato, T., Yokoo, Y., Itoh, S., Yoshida, M., Yoshiki, T., Akiyoshi, K., Sunamoto, J., Nakayama, E. J. Immunol. (1991) [Pubmed]
  4. Antibodies to retroviral proteins and reverse transcriptase activity in patients with essential cryoglobulinemia. Perl, A., Gorevic, P.D., Condemi, J.J., Papsidero, L., Poiesz, B.J., Abraham, G.N. Arthritis Rheum. (1991) [Pubmed]
  5. Identification of a neutralization epitope on the envelope gp46 antigen of human T cell leukemia virus type I and induction of neutralizing antibody by peptide immunization. Tanaka, Y., Zeng, L., Shiraki, H., Shida, H., Tozawa, H. J. Immunol. (1991) [Pubmed]
  6. Immunogenicity of human T cell leukemia virus type-I (HTLV-I) antigens for cytotoxic T lymphocytes in the rat system. Tanaka, Y., Isobe, A., Masuda, M., Tozawa, H., Koyanagi, Y., Yamamoto, N., Shida, H. J. Immunol. (1991) [Pubmed]
  7. IgM secreted by human T lymphoma virus-I-infected and transformed human B cell clones recognize a 66-kilodalton host-encoded protein. Ng, V.L., Rainer, C., Oliver, M.R., Marsh, J., Wood, P., Reyes, G.R., McGrath, M.S. J. Immunol. (1989) [Pubmed]
  8. Functional role of pX open reading frame II of human T-lymphotropic virus type 1 in maintenance of viral loads in vivo. Bartoe, J.T., Albrecht, B., Collins, N.D., Robek, M.D., Ratner, L., Green, P.L., Lairmore, M.D. J. Virol. (2000) [Pubmed]
  9. Broad host range of human T-cell leukemia virus type 1 demonstrated with an improved pseudotyping system. Sutton, R.E., Littman, D.R. J. Virol. (1996) [Pubmed]
  10. Relationship between the anti-HTLV-1 antibody level, the number of abnormal lymphocytes and the viral-genome dose in HTLV-1-infected individuals. Shinzato, O., Kamihira, S., Ikeda, S., Kondo, H., Kanda, T., Nagata, Y., Nakayama, E., Shiku, H. Int. J. Cancer (1993) [Pubmed]
  11. Expression and immunogenicity in rats of recombinant adenovirus 5 DNA plasmids and vaccinia virus containing the HTLV-I env gene. Kazanji, M., Bomford, R., Bessereau, J.L., Schulz, T., de Thé, G. Int. J. Cancer (1997) [Pubmed]
  12. Human T lymphotropic virus types I- and II-specific antibody-dependent cellular cytotoxicity: strain specificity and epitope mapping. Zhang, X.Q., Yang, L., Ho, D.D., Kuritzkes, D.R., Chen, I.S., Ching, W.T., Chen, Y.M., Schooley, R.T. J. Infect. Dis. (1992) [Pubmed]
  13. HTLV-I/HTLV-II coinfection in an AIDS patient from São Paulo, Brazil. Caterino-de-Araujo, A., Favero, A., de los Santos-Fortuna, E., Suleiman, J., Chieco-Bianchi, L., Calabrò, M.L. AIDS Res. Hum. Retroviruses (2000) [Pubmed]
  14. Characterization of HTLV-I isolates and T lymphoid cell lines derived from French West Indian patients with tropical spastic paraparesis. Gessain, A., Saal, F., Morozov, V., Lasneret, J., Vilette, D., Gout, O., Emanoil-Ravier, R., Sigaux, F., de Thé, G., Périès, J. Int. J. Cancer (1989) [Pubmed]
  15. Human T-lymphotropic virus type I DNA in spinal cord of tropical spastic paraparesis with concomitant human T-lymphotropic virus type I-negative Hodgkin's disease. Navarro-Román, L., Corbin, D.O., Katz, D., Callender, D.P., Prussia, P.R., Garriques, S., Fraser, H.S., Jaffe, E.S., Román, G.C. Hum. Pathol. (1994) [Pubmed]
  16. Clinicopathological and virological analyses of familial human T-lymphotropic virus type I--associated polyneuropathy. Sawa, H., Nagashima, T., Nagashima, K., Shinohara, T., Chuma, T., Mano, Y., Tachi, N., Hall, W.W. J. Neurovirol. (2005) [Pubmed]
  17. Expression of human T-cell leukaemia virus type I and associated antigens, and interleukin-2 and receptor in lymph nodes of adult T-cell leukaemia/lymphoma. Ohshima, K., Kikuchi, M., Kobari, S., Shiraki, H., Sumiyoshi, Y., Yoneda, S., Masuda, Y., Takeshita, M., Kimura, N. Virchows Arch. (1994) [Pubmed]
  18. Induction of neutralizing antibodies against HTLV-I envelope proteins after combined genetic and protein immunizations in mice. Grange, M.P., Armand, M.A., Audoly, G., Thollot, D., Desgranges, C. DNA Cell Biol. (1997) [Pubmed]
  19. Absence of human T-lymphotrophic virus type I in patients with systemic lupus erythematosus. Lipka, K., Tebbe, B., Finckh, U., Rolfs, A. Clin. Exp. Dermatol. (1996) [Pubmed]
  20. Identification of new epitopes recognized by human monoclonal antibodies with neutralizing and antibody-dependent cellular cytotoxicity activities specific for human T cell leukemia virus type 1. Kuroki, M., Nakamura, M., Itoyama, Y., Tanaka, Y., Shiraki, H., Baba, E., Esaki, T., Tatsumoto, T., Nagafuchi, S., Nakano, S. J. Immunol. (1992) [Pubmed]
  21. Molecular epidemiology of 58 new African human T-cell leukemia virus type 1 (HTLV-1) strains: identification of a new and distinct HTLV-1 molecular subtype in Central Africa and in Pygmies. Mahieux, R., Ibrahim, F., Mauclere, P., Herve, V., Michel, P., Tekaia, F., Chappey, C., Garin, B., Van Der Ryst, E., Guillemain, B., Ledru, E., Delaporte, E., de The, G., Gessain, A. J. Virol. (1997) [Pubmed]
  22. Effect of immunization on HTLV-I infection in rabbits. Takehara, N., Iwahara, Y., Uemura, Y., Sawada, T., Ohtsuki, Y., Iwai, H., Hoshino, H., Miyoshi, I. Int. J. Cancer (1989) [Pubmed]
  23. Immunologic and virologic characterization of the primary infiltrating cells in the aqueous humor of human T-cell leukemia virus type-1 uveitis. Accumulation of the human T-cell leukemia virus type-1-infected cells and constitutive expression of viral and interleukin-6 messenger ribonucleic acids. Ono, A., Mochizuki, M., Yamaguchi, K., Miyata, N., Watanabe, T. Invest. Ophthalmol. Vis. Sci. (1997) [Pubmed]
  24. Development and evaluation of a human T-cell leukemia virus type I serologic confirmatory assay incorporating a recombinant envelope polypeptide. Lillehoj, E.P., Alexander, S.S., Dubrule, C.J., Wiktor, S., Adams, R., Tai, C.C., Manns, A., Blattner, W.A. J. Clin. Microbiol. (1990) [Pubmed]
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