Gene Review:
Ppp3ca - protein phosphatase 3, catalytic subunit,...
Mus musculus
Synonyms:
2900074D19Rik, AI841391, AW413465, CAM-PRP catalytic subunit, CN, ...
- Calcineurin activity is regulated both by redox compounds and by mutant familial amyotrophic lateral sclerosis-superoxide dismutase. Ferri, A., Gabbianelli, R., Casciati, A., Paolucci, E., Rotilio, G., Carrì, M.T. J. Neurochem. (2000)
- Time-dependent systolic and diastolic function in mice overexpressing calcineurin. Semeniuk, L.M., Severson, D.L., Kryski, A.J., Swirp, S.L., Molkentin, J.D., Duff, H.J. Am. J. Physiol. Heart Circ. Physiol. (2003)
- Decrease in density of INa is in the common final pathway to heart block in murine hearts overexpressing calcineurin. Guo, J., Zhan, S., Somers, J., Westenbroek, R.E., Catterall, W.A., Roach, D.E., Sheldon, R.S., Lees-Miller, J.P., Li, P., Shimoni, Y., Duff, H.J. Am. J. Physiol. Heart Circ. Physiol. (2006)
- Calcineurin differentially regulates maintenance and growth of phenotypically distinct muscles. Mitchell, P.O., Mills, S.T., Pavlath, G.K. Am. J. Physiol., Cell Physiol. (2002)
- Differential expression of calmodulin-binding proteins in B, T lymphocytes and thymocytes. Kincaid, R.L., Takayama, H., Billingsley, M.L., Sitkovsky, M.V. Nature (1987)
- X-linked B-lymphocyte immune defect in CBA/N mice. II. Studies of the mechanisms underlying the immune defect. Scher, I., Steinberg, A.D., Berning, A.K., Paul, W.E. J. Exp. Med. (1975)
- Matching of calcineurin activity to upstream effectors is critical for skeletal muscle fiber growth. Dunn, S.E., Chin, E.R., Michel, R.N. J. Cell Biol. (2000)
- Ectopic expression of the homeobox gene Cux-1 rescues calcineurin inhibition in mouse embryonic kidney cultures. Alcalay, N.I., Brantley, J.G., Sharma, M., Gooch, J.L., Vanden Heuvel, G.B. Dev. Dyn. (2007)
- Investigating Gene-to-Behavior Pathways in Psychiatric Disorders: The Use of a Comprehensive Behavioral Test Battery on Genetically Engineered Mice. Takao, K., Miyakawa, T. Ann. N. Y. Acad. Sci. (2006)
- Cloning and characterization of molecular isoforms of the catalytic subunit of calcineurin using nonisotopic methods. Kincaid, R.L., Giri, P.R., Higuchi, S., Tamura, J., Dixon, S.C., Marietta, C.A., Amorese, D.A., Martin, B.M. J. Biol. Chem. (1990)
- Calcineurin A-alpha but not A-beta is required for normal kidney development and function. Gooch, J.L., Toro, J.J., Guler, R.L., Barnes, J.L. Am. J. Pathol. (2004)
- Ca2+/calmodulin-dependent protein phosphatase calcineurin mediates the expression of iNOS through IKK and NF-kappaB activity in LPS-stimulated mouse peritoneal macrophages and RAW 264.7 cells. Kim, Y., Moon, J.S., Lee, K.S., Park, S.Y., Cheong, J., Kang, H.S., Lee, H.Y., Kim, H.D. Biochem. Biophys. Res. Commun. (2004)
- Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia. Miyakawa, T., Leiter, L.M., Gerber, D.J., Gainetdinov, R.R., Sotnikova, T.D., Zeng, H., Caron, M.G., Tonegawa, S. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Stimulation of calcineurin signaling attenuates the dystrophic pathology in mdx mice. Chakkalakal, J.V., Harrison, M.A., Carbonetto, S., Chin, E., Michel, R.N., Jasmin, B.J. Hum. Mol. Genet. (2004)
- Molecular and phylogenetic analysis of calmodulin-dependent protein phosphatase (calcineurin) catalytic subunit genes. Giri, P.R., Marietta, C.A., Higuchi, S., Kincaid, R.L. DNA Cell Biol. (1992)
- Synergism between the calmodulin-binding and autoinhibitory domains on calcineurin is essential for the induction of their phosphatase activity. Tokoyoda, K., Takemoto, Y., Nakayama, T., Arai, T., Kubo, M. J. Biol. Chem. (2000)
- Calcineurin mediates pancreatic growth in protease inhibitor-treated mice. Tashiro, M., Samuelson, L.C., Liddle, R.A., Williams, J.A. Am. J. Physiol. Gastrointest. Liver Physiol. (2004)
- An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle. Handschin, C., Rhee, J., Lin, J., Tarr, P.T., Spiegelman, B.M. Proc. Natl. Acad. Sci. U.S.A. (2003)
- The effect of calcineurin activator, extracted from Chinese herbal medicine, on memory and immunity in mice. Luo, J., Yin, J.H., Wei, Q. Pharmacol. Biochem. Behav. (2003)