Gene Review:
PPP3CA - protein phosphatase 3, catalytic subunit,...
Bos taurus
- Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy. Taigen, T., De Windt, L.J., Lim, H.W., Molkentin, J.D. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Characterization of a cDNA clone encoding the calmodulin-binding domain of mouse brain calcineurin. Kincaid, R.L., Nightingale, M.S., Martin, B.M. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Characterization of the phosphatase activity of a baculovirus-expressed calcineurin A isoform. Perrino, B.A., Fong, Y.L., Brickey, D.A., Saitoh, Y., Ushio, Y., Fukunaga, K., Miyamoto, E., Soderling, T.R. J. Biol. Chem. (1992)
- Dephosphorylation of endothelial nitric-oxide synthase by vascular endothelial growth factor. Implications for the vascular responses to cyclosporin A. Kou, R., Greif, D., Michel, T. J. Biol. Chem. (2002)
- The Caenorhabditis elegans homologue of Down syndrome critical region 1, RCN-1, inhibits multiple functions of the phosphatase calcineurin. Lee, J.I., Dhakal, B.K., Lee, J., Bandyopadhyay, J., Jeong, S.Y., Eom, S.H., Kim, d.o. .H., Ahnn, J. J. Mol. Biol. (2003)
- X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex. Griffith, J.P., Kim, J.L., Kim, E.E., Sintchak, M.D., Thomson, J.A., Fitzgibbon, M.J., Fleming, M.A., Caron, P.R., Hsiao, K., Navia, M.A. Cell (1995)
- Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin. Chang, H.Y., Takei, K., Sydor, A.M., Born, T., Rusnak, F., Jay, D.G. Nature (1995)
- Localization of calcineurin in the mature and developing retina. Nakazawa, A., Usuda, N., Matsui, T., Hanai, T., Matsushita, S., Arai, H., Sasaki, H., Higuchi, S. J. Histochem. Cytochem. (2001)
- Response of recombinant calcineurin to metal ions, reduction-oxidation agents, and enzymatic modification. Rhode, D.J., Imparl-Radosevich, J., Bartleson, C., Spannaus-Martin, D.J., Martin, B.L. Protein Expr. Purif. (2002)
- Roles of peptidyl-prolyl cis-trans isomerase and calcineurin in the mechanisms of antimalarial action of cyclosporin A, FK506, and rapamycin. Bell, A., Wernli, B., Franklin, R.M. Biochem. Pharmacol. (1994)
- FKBP12-FK506 complex inhibits phosphatase activity of two mammalian isoforms of calcineurin irrespective of their substrates or activation mechanisms. Mukai, H., Kuno, T., Chang, C.D., Lane, B., Luly, J.R., Tanaka, C. J. Biochem. (1993)
- Molecular cloning, expression, purification and characterization of calcineurin from bovine cardiac muscle. Selvakumar, P., Lakshmikuttyamma, A., Anderson, D.H., Sharma, R.K. Biochimie (2005)
- FK506 inhibits Cl- secretion in airway epithelium via calcineurin-independent mechanism. Kanoh, S., Kondo, M., Tamaoki, J., Kobayashi, H., Motoyoshi, K., Nagai, A. Eur. J. Pharmacol. (2001)
- Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain. Guerini, D., Klee, C.B. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Evidence for participation of calcineurin in potentiation of agonist-stimulated cyclic AMP formation by the calcium-mobilizing hormone, angiotensin II. Baukal, A.J., Hunyady, L., Catt, K.J., Balla, T. J. Biol. Chem. (1994)
- The sites at which brain microtubule-associated protein 2 is phosphorylated in vivo differ from those accessible to cAMP-dependent kinase in vitro. Murthy, A.S., Bramblett, G.T., Flavin, M. J. Biol. Chem. (1985)
- Function and structure of recombinant single chain calcineurin. Qin, Y.L., Yu, D.Y., Wei, Q. Biochem. Biophys. Res. Commun. (2003)
- pCyP B: a chloroplast-localized, heat shock-responsive cyclophilin from fava bean. Luan, S., Lane, W.S., Schreiber, S.L. Plant Cell (1994)
- Specific interaction of the cyclophilin-cyclosporin complex with the B subunit of calcineurin. Li, W., Handschumacher, R.E. J. Biol. Chem. (1993)
- Detection of the FK506-FKBP-calcineurin complex by a simple binding assay. Asami, M., Kuno, T., Mukai, H., Tanaka, C. Biochem. Biophys. Res. Commun. (1993)
- Binding of active cyclosporins to cyclophilin A and B, complex formation with calcineurin A. Ryffel, B., Woerly, G., Murray, M., Eugster, H.P., Car, B. Biochem. Biophys. Res. Commun. (1993)
- Dephosphorylation of microtubule-associated protein 2, tau factor, and tubulin by calcineurin. Goto, S., Yamamoto, H., Fukunaga, K., Iwasa, T., Matsukado, Y., Miyamoto, E. J. Neurochem. (1985)
- Dopamine- and cAMP-regulated phosphoprotein DARPP-32: phosphorylation of Ser-137 by casein kinase I inhibits dephosphorylation of Thr-34 by calcineurin. Desdouits, F., Siciliano, J.C., Greengard, P., Girault, J.A. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Characterization of phosphotyrosyl-protein phosphatase activity associated with calcineurin. Chernoff, J., Sells, M.A., Li, H.C. Biochem. Biophys. Res. Commun. (1984)
- Modulation of calcineurin phosphotyrosyl protein phosphatase activity by calmodulin and protease treatment. Kincaid, R.L., Martensen, T.M., Vaughan, M. Biochem. Biophys. Res. Commun. (1986)
- Molecular cloning of bovine cardiac muscle heat-shock protein 70 kDa and its phosphorylation by cAMP-dependent protein kinase in vitro. Lakshmikuttyamma, A., Selvakumar, P., Anderson, D.H., Datla, R.S., Sharma, R.K. Biochemistry (2004)
- Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A and B. Swanson, S.K., Born, T., Zydowsky, L.D., Cho, H., Chang, H.Y., Walsh, C.T., Rusnak, F. Proc. Natl. Acad. Sci. U.S.A. (1992)
- A calcium-initiated signaling pathway propagated through calcineurin and cAMP response element-binding protein activates proenkephalin gene transcription after depolarization. Hahm, S.H., Chen, Y., Vinson, C., Eiden, L.E. Mol. Pharmacol. (2003)
- Pituitary adenylate cyclase-activating polypeptide regulation of vasoactive intestinal polypeptide transcription requires Ca2+ influx and activation of the serine/threonine phosphatase calcineurin. Lee, H.W., Hahm, S.H., Hsu, C.M., Eiden, L.E. J. Neurochem. (1999)
- A rapid and sensitive method for detection and quantification of calcineurin and calmodulin-binding proteins using biotinylated calmodulin. Billingsley, M.L., Pennypacker, K.R., Hoover, C.G., Brigati, D.J., Kincaid, R.L. Proc. Natl. Acad. Sci. U.S.A. (1985)
- Stoichiometry and dynamic interaction of metal ion activators with calcineurin phosphatase. Pallen, C.J., Wang, J.H. J. Biol. Chem. (1986)