Gene Review:
NLRP1 - NLR family, pyrin domain containing 1
Homo sapiens
Synonyms:
CARD7, CIDED, CLR17.1, Caspase recruitment domain-containing protein 7, DEFCAP, ...
- Expression of NALP1 in cerebellar granule neurons stimulates apoptosis. Liu, F., Lo, C.F., Ning, X., Kajkowski, E.M., Jin, M., Chiriac, C., Gonzales, C., Naureckiene, S., Lock, Y.W., Pong, K., Zaleska, M.M., Jacobsen, J.S., Silverman, S., Ozenberger, B.A. Cell. Signal. (2004)
- Genetic differentiation of appendiceal tumor malignancy: a guide for the perplexed. Modlin, I.M., Kidd, M., Latich, I., Zikusoka, M.N., Eick, G.N., Mane, S.M., Camp, R.L. Ann. Surg. (2006)
- NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells. Sanz, C., Calasanz, M.J., Andreu, E., Richard, C., Prosper, F., Fernandez-Luna, J.L. Biochem. J. (2004)
- NALP1 in vitiligo-associated multiple autoimmune disease. Jin, Y., Mailloux, C.M., Gowan, K., Riccardi, S.L., LaBerge, G., Bennett, D.C., Fain, P.R., Spritz, R.A. N. Engl. J. Med. (2007)
- Identification of the region of non-Abeta component (NAC) of Alzheimer's disease amyloid responsible for its aggregation and toxicity. Bodles, A.M., Guthrie, D.J., Greer, B., Irvine, G.B. J. Neurochem. (2001)
- Synuclein proteins and Alzheimer's disease. Brookes, A.J., St Clair, D. Trends Neurosci. (1994)
- NALPs: a novel protein family involved in inflammation. Tschopp, J., Martinon, F., Burns, K. Nat. Rev. Mol. Cell Biol. (2003)
- NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Agostini, L., Martinon, F., Burns, K., McDermott, M.F., Hawkins, P.N., Tschopp, J. Immunity (2004)
- mRNA expression profiles for Escherichia coli ingested by normal and phagocyte oxidase-deficient human neutrophils. Staudinger, B.J., Oberdoerster, M.A., Lewis, P.J., Rosen, H. J. Clin. Invest. (2002)
- A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways. Rosenstiel, P., Huse, K., Till, A., Hampe, J., Hellmig, S., Sina, C., Billmann, S., von Kampen, O., Waetzig, G.H., Platzer, M., Seegert, D., Schreiber, S. Proc. Natl. Acad. Sci. U.S.A. (2006)
- NAC transcription factors: structurally distinct, functionally diverse. Olsen, A.N., Ernst, H.A., Leggio, L.L., Skriver, K. Trends Plant Sci. (2005)
- Generation of reactive oxygen species and activation of NF-kappaB by non-Abeta component of Alzheimer's disease amyloid. Tanaka, S., Takehashi, M., Matoh, N., Iida, S., Suzuki, T., Futaki, S., Hamada, H., Masliah, E., Sugiura, Y., Ueda, K. J. Neurochem. (2002)
- TNFalpha induces chromosomal abnormalities independent of ROS through IKK, JNK, p38 and caspase pathways. Higashimoto, T., Panopoulos, A., Hsieh, C.L., Zandi, E. Cytokine (2006)
- Prevention of impulse noise-induced hearing loss with antioxidants. Kopke, R., Bielefeld, E., Liu, J., Zheng, J., Jackson, R., Henderson, D., Coleman, J.K. Acta Otolaryngol. (2005)
- Genetic control of shoot organ boundaries. Aida, M., Tasaka, M. Curr. Opin. Plant Biol. (2006)
- Methylglyoxal enhances cisplatin-induced cytotoxicity by activating protein kinase Cdelta. Godbout, J.P., Pesavento, J., Hartman, M.E., Manson, S.R., Freund, G.G. J. Biol. Chem. (2002)
- beta-D-Glucoside suppresses tumor necrosis factor-induced activation of nuclear transcription factor kappaB but potentiates apoptosis. Sarkar, A., Sreenivasan, Y., Ramesh, G.T., Manna, S.K. J. Biol. Chem. (2004)
- Thermodynamics and stability of the PAAD/DAPIN/PYRIN domain of IFI-16. Dalal, K., Pio, F. FEBS Lett. (2006)
- Structure and Dynamics of ASC2, a Pyrin Domain-only Protein That Regulates Inflammatory Signaling. Natarajan, A., Ghose, R., Hill, J.M. J. Biol. Chem. (2006)
- Relief of cancer pain in man: alcohol-induced neuroadenolysis vs. electrical stimulation of the pituitary gland. Yanagida, H., Corssen, G., Trouwborst, A., Erdmann, W. Pain (1984)
- The effects of aggregation-inducing motifs on amyloid formation of model proteins related to neurodegenerative diseases. Tanaka, M., Machida, Y., Nishikawa, Y., Akagi, T., Morishima, I., Hashikawa, T., Fujisawa, T., Nukina, N. Biochemistry (2002)
- Isoform-specific binding of human apolipoprotein E to the non-amyloid beta component of Alzheimer's disease amyloid. Olesen, O.F., Mikkelsen, J.D., Gerdes, C., Jensen, P.H. Brain Res. Mol. Brain Res. (1997)