Gene Review:
C1QBP - complement component 1, q subcomponent...
Homo sapiens
Synonyms:
ASF/SF2-associated protein p32, C1qBP, Complement component 1 Q subcomponent-binding protein, mitochondrial, GC1QBP, Glycoprotein gC1qBP, ...
Howat,
Ruf,
Guillaume,
Moorman,
Chi,
Lee,
Murphy,
Edwards,
Peerschke,
Ghebrehiwet,
Bayliss,
Barry,
Prayther,
Ghebrehiwet,
Lecuit,
Murphy,
Rubinstein,
Dudhia,
Ghebrehiwet,
Stortchevoi,
Fitzgerald,
Boosalis,
Ashfaq,
Day,
Krishnaswamy,
Kaplan,
Joseph,
Pizarro-Cerdá,
Cossart,
Peerschke,
Tholanikunnel,
Calvo,
Petrovan,
Peerschke,
Ghebrehiwet,
- Receptor for the globular heads of C1q (gC1q-R, p33, hyaluronan-binding protein) is preferentially expressed by adenocarcinoma cells. Rubinstein, D.B., Stortchevoi, A., Boosalis, M., Ashfaq, R., Ghebrehiwet, B., Peerschke, E.I., Calvo, F., Guillaume, T. Int. J. Cancer (2004)
- Human p32 protein relieves a post-transcriptional block to HIV replication in murine cells. Zheng, Y.H., Yu, H.F., Peterlin, B.M. Nat. Cell Biol. (2003)
- gC1q-R/p32, a C1q-binding protein, is a receptor for the InlB invasion protein of Listeria monocytogenes. Braun, L., Ghebrehiwet, B., Cossart, P. EMBO J. (2000)
- gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway. Waggoner, S.N., Cruise, M.W., Kassel, R., Hahn, Y.S. J. Immunol. (2005)
- The overexpression of RHAMM, a hyaluronan-binding protein that regulates ras signaling, correlates with overexpression of mitogen-activated protein kinase and is a significant parameter in breast cancer progression. Wang, C., Thor, A.D., Moore, D.H., Zhao, Y., Kerschmann, R., Stern, R., Watson, P.H., Turley, E.A. Clin. Cancer Res. (1998)
- Structural chromosomal anomaly in mental retardation. Reddy, K.S., Rajangam, S., Thomas, I.M. Indian journal of pediatrics. (1999)
- Formation of bradykinin: a major contributor to the innate inflammatory response. Joseph, K., Kaplan, A.P. Adv. Immunol. (2005)
- Invasion of mammalian cells by Listeria monocytogenes: functional mimicry to subvert cellular functions. Cossart, P., Pizarro-Cerdá, J., Lecuit, M. Trends Cell Biol. (2003)
- Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation. Kittlesen, D.J., Chianese-Bullock, K.A., Yao, Z.Q., Braciale, T.J., Hahn, Y.S. J. Clin. Invest. (2000)
- Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules. Kang, S.J., Cresswell, P. EMBO J. (2002)
- The hemopexin-like C-terminal domain of membrane type 1 matrix metalloproteinase regulates proteolysis of a multifunctional protein, gC1qR. Rozanov, D.V., Ghebrehiwet, B., Postnova, T.I., Eichinger, A., Deryugina, E.I., Strongin, A.Y. J. Biol. Chem. (2002)
- Hyaluronan binding protein 1 (HABP1)/C1QBP/p32 is an endogenous substrate for MAP kinase and is translocated to the nucleus upon mitogenic stimulation. Majumdar, M., Meenakshi, J., Goswami, S.K., Datta, K. Biochem. Biophys. Res. Commun. (2002)
- The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation. Petersen-Mahrt, S.K., Estmer, C., Ohrmalm, C., Matthews, D.A., Russell, W.C., Akusjärvi, G. EMBO J. (1999)
- Classical pathway complement activation on human endothelial cells. Yin, W., Ghebrehiwet, B., Weksler, B., Peerschke, E.I. Mol. Immunol. (2007)
- Upregulation of hyaluronan binding protein 1 (HABP1/p32/gC1qR) is associated with Cisplatin induced apoptosis. Kamal, A., Datta, K. Apoptosis (2006)
- Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro. Chattopadhyay, C., Hawke, D., Kobayashi, R., Maity, S.N. Nucleic Acids Res. (2004)
- Hepatitis C virus core protein inhibits human T lymphocyte responses by a complement-dependent regulatory pathway. Yao, Z.Q., Nguyen, D.T., Hiotellis, A.I., Hahn, Y.S. J. Immunol. (2001)
- Hepatitis C virus core selectively suppresses interleukin-12 synthesis in human macrophages by interfering with AP-1 activation. Eisen-Vandervelde, A.L., Waggoner, S.N., Yao, Z.Q., Cale, E.M., Hahn, C.S., Hahn, Y.S. J. Biol. Chem. (2004)
- Protein kinase C [micro] is regulated by the multifunctional chaperon protein p32. Storz, P., Hausser, A., Link, G., Dedio, J., Ghebrehiwet, B., Pfizenmaier, K., Johannes, F.J. J. Biol. Chem. (2000)
- Activation-dependent surface expression of gC1qR/p33 on human blood platelets. Peerschke, E.I., Murphy, T.K., Ghebrehiwet, B. Thromb. Haemost. (2003)
- Cellular splicing and transcription regulatory protein p32 represses adenovirus major late transcription and causes hyperphosphorylation of RNA polymerase II. Ohrmalm, C., Akusjärvi, G. J. Virol. (2006)
- Tissue factor pathway inhibitor-2 (TFPI-2) recognizes the complement and kininogen binding protein gC1qR/p33 (gC1qR): implications for vascular inflammation. Peerschke, E.I., Petrovan, R.J., Ghebrehiwet, B., Ruf, W. Thromb. Haemost. (2004)
- HABP1/p32/gC1qR induces aberrant growth and morphology in Schizosaccharomyces pombe through its N-terminal alpha helix. Mallick, J., Datta, K. Exp. Cell Res. (2005)
- Interaction of high molecular weight kininogen binding proteins on endothelial cells. Joseph, K., Tholanikunnel, B.G., Ghebrehiwet, B., Kaplan, A.P. Thromb. Haemost. (2004)
- Induction of p38- and gC1qR-dependent IL-8 expression in pulmonary fibroblasts by soluble hepatitis C core protein. Moorman, J.P., Fitzgerald, S.M., Prayther, D.C., Lee, S.A., Chi, D.S., Krishnaswamy, G. Respir. Res. (2005)
- SOCS1 and SOCS3 are targeted by hepatitis C virus core/gC1qR ligation to inhibit T-cell function. Yao, Z.Q., Waggoner, S.N., Cruise, M.W., Hall, C., Xie, X., Oldach, D.W., Hahn, Y.S. J. Virol. (2005)
- TSG-6 expression in human articular chondrocytes. Possible implications in joint inflammation and cartilage degradation. Maier, R., Wisniewski, H.G., Vilcek, J., Lotz, M. Arthritis Rheum. (1996)
- Up-regulation and differential expression of the hyaluronan-binding protein TSG-6 in cartilage and synovium in rheumatoid arthritis and osteoarthritis. Bayliss, M.T., Howat, S.L., Dudhia, J., Murphy, J.M., Barry, F.P., Edwards, J.C., Day, A.J. Osteoarthr. Cartil. (2001)
- Constitutive expression of hyaluronan binding protein 1 (HABP1/p32/gC1qR) in normal fibroblast cells perturbs its growth characteristics and induces apoptosis. Meenakshi, J., Anupama, n.u.l.l., Goswami, S.K., Datta, K. Biochem. Biophys. Res. Commun. (2003)
- In vitro interaction between human immunodeficiency virus type 1 Rev protein and splicing factor ASF/SF2-associated protein, p32. Tange, T.O., Jensen, T.H., Kjems, J. J. Biol. Chem. (1996)
- Surface expression of complement receptor gC1q-R/p33 is increased on the plasma membrane of human spermatozoa after capacitation. Grace, K.S., Bronson, R.A., Ghebrehiwet, B. Biol. Reprod. (2002)