Gene Review:
CD27 - CD27 molecule
Homo sapiens
Synonyms:
CD27 antigen, CD27L receptor, S152, T-cell activation antigen CD27, T14, ...
- CD27 and CD57 Expression Reveals Atypical Differentiation of Human Immunodeficiency Virus Type 1-Specific Memory CD8+ T Cells. Hoji, A., Connolly, N.C., Buchanan, W.G., Rinaldo, C.R. Clin. Vaccine Immunol. (2007)
- Bacterial CpG induces hyper-IgM production in CD27(+) memory B cells in primary biliary cirrhosis. Kikuchi, K., Lian, Z.X., Yang, G.X., Ansari, A.A., Ikehara, S., Kaplan, M., Miyakawa, H., Coppel, R.L., Gershwin, M.E. Gastroenterology (2005)
- Signaling through CD70 regulates B cell activation and IgG production. Arens, R., Nolte, M.A., Tesselaar, K., Heemskerk, B., Reedquist, K.A., van Lier, R.A., van Oers, M.H. J. Immunol. (2004)
- Loss of memory (CD27) B lymphocytes in HIV-1 infection. De Milito, A., Mörch, C., Sönnerborg, A., Chiodi, F. AIDS (2001)
- CD148 and CD27 are expressed in B cell lymphomas derived from both memory and naïve B cells. Dong, H.Y., Shahsafaei, A., Dorfman, D.M. Leuk. Lymphoma (2002)
- Aberrant expression of CD27 and soluble CD27 (sCD27) in HIV infection and in AIDS-associated lymphoma. Widney, D., Gundapp, G., Said, J.W., van der Meijden, M., Bonavida, B., Demidem, A., Trevisan, C., Taylor, J., Detels, R., Martínez-Maza, O. Clin. Immunol. (1999)
- Low levels of specific T cell activation marker CD27 accompanied by elevated levels of markers for non-specific immune activation in the cerebrospinal fluid of patients with AIDS dementia complex. Portegies, P., Godfried, M.H., Hintzen, R.Q., Stam, J., van der Poll, T., Bakker, M., van Deventer, S.J., van Lier, R.A., Goudsmit, J. J. Neuroimmunol. (1993)
- Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor. Goodwin, R.G., Alderson, M.R., Smith, C.A., Armitage, R.J., VandenBos, T., Jerzy, R., Tough, T.W., Schoenborn, M.A., Davis-Smith, T., Hennen, K. Cell (1993)
- Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Appay, V., Dunbar, P.R., Callan, M., Klenerman, P., Gillespie, G.M., Papagno, L., Ogg, G.S., King, A., Lechner, F., Spina, C.A., Little, S., Havlir, D.V., Richman, D.D., Gruener, N., Pape, G., Waters, A., Easterbrook, P., Salio, M., Cerundolo, V., McMichael, A.J., Rowland-Jones, S.L. Nat. Med. (2002)
- Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions. Tesselaar, K., Arens, R., van Schijndel, G.M., Baars, P.A., van der Valk, M.A., Borst, J., van Oers, M.H., van Lier, R.A. Nat. Immunol. (2003)
- The requirement for Notch signaling at the {beta}-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor. Maillard, I., Tu, L., Sambandam, A., Yashiro-Ohtani, Y., Millholland, J., Keeshan, K., Shestova, O., Xu, L., Bhandoola, A., Pear, W.S. J. Exp. Med. (2006)
- Serum soluble CD27, but not thymidine kinase, is an independent prognostic factor for outcome in indolent non-Hodgkin's lymphoma. Kok, M., Bonfrer, J.M., Korse, C.M., de Jong, D., Kersten, M.J. Tumour Biol. (2003)
- Virus-induced polyclonal B cell activation improves protective CTL memory via retained CD27 expression on memory CTL. Matter, M., Mumprecht, S., Pinschewer, D.D., Pavelic, V., Yagita, H., Krautwald, S., Borst, J., Ochsenbein, A.F. Eur. J. Immunol. (2005)
- Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport. Loe, D.W., Almquist, K.C., Deeley, R.G., Cole, S.P. J. Biol. Chem. (1996)
- A globally disseminated M1 subclone of group A streptococci differs from other subclones by 70 kilobases of prophage DNA and capacity for high-frequency intracellular invasion. Cleary, P.P., LaPenta, D., Vessela, R., Lam, H., Cue, D. Infect. Immun. (1998)
- Generation of plasma cells from peripheral blood memory B cells: synergistic effect of interleukin-10 and CD27/CD70 interaction. Agematsu, K., Nagumo, H., Oguchi, Y., Nakazawa, T., Fukushima, K., Yasui, K., Ito, S., Kobata, T., Morimoto, C., Komiyama, A. Blood (1998)
- CD27 and CD40 inhibit p53-independent mitochondrial pathways in apoptosis of B cells induced by B cell receptor ligation. Hase, H., Kanno, Y., Kojima, H., Morimoto, C., Okumura, K., Kobata, T. J. Biol. Chem. (2002)
- CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase. Akiba, H., Nakano, H., Nishinaka, S., Shindo, M., Kobata, T., Atsuta, M., Morimoto, C., Ware, C.F., Malinin, N.L., Wallach, D., Yagita, H., Okumura, K. J. Biol. Chem. (1998)
- Isolation and regional assignment of human chromosome 12p cDNAs. Baens, M., Aerssens, J., van Zand, K., Van den Berghe, H., Marynen, P. Genomics (1995)
- The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family. Camerini, D., Walz, G., Loenen, W.A., Borst, J., Seed, B. J. Immunol. (1991)
- Memory B cells and CD27. Agematsu, K. Histol. Histopathol. (2000)
- High levels of serum soluble CD27 correlated with renal dysfunction. Nakatsuji, T. Clin. Exp. Med. (2003)
- S152 (CD27). A modulating disulfide-linked T cell activation antigen. Bigler, R.D., Bushkin, Y., Chiorazzi, N. J. Immunol. (1988)
- Tissue distribution and biochemical and functional properties of Tp55 (CD27), a novel T cell differentiation antigen. van Lier, R.A., Borst, J., Vroom, T.M., Klein, H., Van Mourik, P., Zeijlemaker, W.P., Melief, C.J. J. Immunol. (1987)
- CD27/CD70 interactions regulate T dependent B cell differentiation. Jacquot, S. Immunol. Res. (2000)
- CD27 is a signal-transducing molecule involved in CD45RA+ naive T cell costimulation. Kobata, T., Agematsu, K., Kameoka, J., Schlossman, S.F., Morimoto, C. J. Immunol. (1994)
- Regulation of expression of CD27, a T cell-specific member of a novel family of membrane receptors. de Jong, R., Loenen, W.A., Brouwer, M., van Emmerik, L., de Vries, E.F., Borst, J., van Lier, R.A. J. Immunol. (1991)
- Immune escape for renal cell carcinoma: CD70 mediates apoptosis in lymphocytes. Diegmann, J., Junker, K., Loncarevic, I.F., Michel, S., Schimmel, B., von Eggeling, F. Neoplasia (2006)
- CD27 mediates interleukin-2-independent clonal expansion of the CD8+ T cell without effector differentiation. Carr, J.M., Carrasco, M.J., Thaventhiran, J.E., Bambrough, P.J., Kraman, M., Edwards, A.D., Al-Shamkhani, A., Fearon, D.T. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Identification of CD70-mediated apoptosis of immune effector cells as a novel immune escape pathway of human glioblastoma. Wischhusen, J., Jung, G., Radovanovic, I., Beier, C., Steinbach, J.P., Rimner, A., Huang, H., Schulz, J.B., Ohgaki, H., Aguzzi, A., Rammensee, H.G., Weller, M. Cancer Res. (2002)
- Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway. Py, B., Slomianny, C., Auberger, P., Petit, P.X., Benichou, S. J. Immunol. (2004)
- CD27-triggering on primary plasma cell leukaemia cells has anti-apoptotic effects involving mitogen activated protein kinases. Guikema, J.E., Vellenga, E., Abdulahad, W.H., Hovenga, S., Bos, N.A. Br. J. Haematol. (2004)
- The cloning of CD70 and its identification as the ligand for CD27. Bowman, M.R., Crimmins, M.A., Yetz-Aldape, J., Kriz, R., Kelleher, K., Herrmann, S. J. Immunol. (1994)
- Three Memory Subsets of Human CD8+ T Cells Differently Expressing Three Cytolytic Effector Molecules. Takata, H., Takiguchi, M. J. Immunol. (2006)
- NF-kappaB activation in CD27 signaling: involvement of TNF receptor-associated factors in its signaling and identification of functional region of CD27. Yamamoto, H., Kishimoto, T., Minamoto, S. J. Immunol. (1998)
- CD27 but not CD70 and 4-1BB intragraft gene expression is a risk factor for acute cardiac allograft rejection in humans. Shulzhenko, N., Morgun, A., Chinellato, A.P., Rampim, G.F., Diniz, R.V., Almeida, D.R., Gerbase-DeLima, M. Transplant. Proc. (2002)
- Microarray analysis of gene expression associated with extrapulmonary dissemination of tuberculosis. Kim, D.K., Park, G.M., Hwang, Y.I., Kim, H.J., Han, S.K., Shim, Y.S., Yim, J.J. Respirology (2006)