Disease relevance of Rotator Cuff

• The value of pulsed electromagnetic fields (PEMF) for the treatment of persistent rotator cuff tendinitis was tested in a double-blind controlled study in 29 patients whose symptoms were refractory to steroid injection and other conventional conservative measures [1].
• Rotator cuff tear secondary to chronic synovitis eroding the rotator cuff tendon is a complication of rheumatoid arthritis that has received little attention [2].
• Increased substance P in subacromial bursa and shoulder pain in rotator cuff diseases [3].
• Over a 1-yr period, 102 patients with a clinical diagnosis of either medial or lateral epicondylitis (tennis elbow) or rotator cuff tendonitis were treated with topical applications of dimethyl sulfoxide (DMSO) [4].
• The present study investigates whether VEGF is also involved in the development of shoulder contracture in diabetics with rotator cuff disease [5].

Psychiatry related information on Rotator Cuff

• The Simple Shoulder Test is a patient-based self-assessment device that easily can be incorporated into a busy clinical practice, providing outcome data comparable with complex evaluation systems when evaluating the results of rotator cuff repair [6].

High impact information on Rotator Cuff

• Hydroxyapatite crystals and rotator cuff disorders: comment on the article by Gomoll et al [7].
• Two ultrasonographic findings were selectively observed in the dialysis patients with clinical and histologic evidence of beta 2m amyloid in comparison with patients with normal renal function and no evidence of amyloid: rotator cuffs greater than 8 mm in thickness and echogenic pads between muscle groups of the rotator cuff [8].
• Rotator cuff tears in rheumatoid arthritis [2].
• CONCLUSION: Proton MR spectroscopy is suitable in the assessment of apparent lipid content of rotator cuff muscles [9].
• The algorithm was tested on coronal images of the rotator cuff in a series of 144 patients, and the improvements in image quality were similar to those achieved with navigator echoes [10].

Chemical compound and disease context of Rotator Cuff

• We used titanium anchors for the surgical repair of rotator cuff tears in 34 selected patients, all of whom were < 60 years of age, had good bone quality, and had no known metabolic bone diseases [11].
• Intraarticular morphine and bupivacaine reduces postoperative pain after rotator cuff repair [12].
• Fifty-five patients with shoulder pain due to rotator cuff tendinitis of less than 12 weeks' duration were randomized to receive either 40 mg methylprednisolone and lignocaine or lignocaine alone [13].

Biological context of Rotator Cuff

• In vitro oxidative stress was created by exposure of cultured human rotator cuff tendon cells to H(2)O(2) [14].
• CONCLUSIONS: Arthroscopic synovectomy of the shoulder in patients with rheumatoid arthritis with an intact rotator cuff offers a reliable decrease in pain with less predictable improvements in range of motion [15].

Anatomical context of Rotator Cuff

• "Milwaukee shoulder"--association of microspheroids containing hydroxyapatite crystals, active collagenase, and neutral protease with rotator cuff defects. II. Synovial fluid studies [16].
• Nerve fibers immunoreactive to substance P were localized around the vessels, with a larger number of fibers in the group with the nonperforated rotator cuff [3].
• Vascular endothelial growth factor 121 and 165 in the subacromial bursa are involved in shoulder joint contracture in type II diabetics with rotator cuff disease [5].
• To examine the involvement of osteopontin (OPN), a potent regulator of calcium deposition on connective tissues, localization and expression of OPN protein and messenger (m)RNA were investigated in human tissue samples of calcified rotator cuff tendons [17].
• This case shows that the terrible triad of the shoulder-anterior dislocation, brachial plexus injury, and rotator cuff tear-can occur in younger populations than previously described [18].

Associations of Rotator Cuff with chemical compounds

• Arthrographic visualization of rotator cuff tears. Optimal application of stress to the shoulder [19].
• The amount of substance P in the subacromial bursa of patients with rotator cuff disease was examined [3].
• The scores for the Western Ontario Rotator Cuff Index at 3 months were xylocaine = 45.4% +/- 13% and betamethasone = 56.3% +/- 17% (P = .13) [20].
• HYPOTHESIS: Augmentation with a woven polylactic acid scaffold strengthens repairs of the rotator cuff [21].
• Our results indicate no significant differences in fixation strength of Bankart lesions or rotator cuff repairs using sutures only, or using wedge or rod polyacetal suture anchors (P = 0.70) [22].

Gene context of Rotator Cuff

• Matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase mRNA levels are specifically altered in torn rotator cuff tendons [23].
• Western blotting demonstrated an increase in the active form of collagenase-3 (MMP-13) in rotator cuff tendon tears [23].
• CONCLUSIONS: A high level of expression of inflammatory cytokines, proteinases, and cyclooxygenase enzymes, known to produce a catabolic environment, is present in the subacromial bursa of patients with rotator cuff tear [24].
• We reported that VEGF is involved in motion pain of patients with rotator cuff disease by causing synovial proliferation in the subacromial bursa (SAB) [5].
• We investigated the pattern of expression of cytokines (interleukin [IL]-1beta, IL-1, IL-6, tumor necrosis factor [TNF] alpha, small inducible cytokines), metalloproteases, and cyclooxygenases in the subacromial bursa in patients with rotator cuff disease [25].

Analytical, diagnostic and therapeutic context of Rotator Cuff

• CONCLUSIONS: Total shoulder arthroplasty with the Delta III prosthesis is a salvage procedure for severe shoulder dysfunction caused by an irreparable rotator cuff tear associated with other glenohumeral lesions [26].
• The use of DMSO in tennis elbow and rotator cuff tendonitis: a double-blind study [4].
• Analgesia after arthroscopic rotator cuff repair: subacromial versus interscalene continuous infusion of ropivacaine [27].
• MR arthrography of the shoulder with gadopentetate dimeglumine has been proved to be valuable in the diagnosis of injuries of the rotator cuff and glenoid labrum [28].
• CASE REPORTS: Four patients scheduled for rotator cuff repair under CIBPB were discharged home the day of surgery with an interscalene catheter connected to an automated infusion pump administering 0.2% ropivacaine at 10 mL x hr(-1) for 72 hr [29].

References