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MeSH Review

Mice, Inbred SENCAR

 
 
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Disease relevance of Mice, Inbred SENCAR

 

Psychiatry related information on Mice, Inbred SENCAR

  • To histologically define the effect of low dietary calcium on bone metabolism, we performed histomorphometric analysis of tetracycline-labeled sections of femoral bone from male SENCAR mice maintained on calcium-sufficient and calcium-deficient diets during the critical period from 10 to 14 weeks of age [6].
 

High impact information on Mice, Inbred SENCAR

  • Furthermore, in the NMRI mouse, PRA is a much more potent second-stage promoter than mezerein, recently reported to be an incomplete promoter in the Sencar mouse [7].
  • The effects of fluocinolone acetonide (FA), retinoic acid (RA), and tosylphenylalanine chloromethyl ketone (TPCK) on two-stage promotion after 7,12-dimethylbenz[a]-anthracene (DMBA) initiation in female Sencar mice were investigated [8].
  • A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model [9].
  • Preapplication of GE onto the skin of SENCAR mice resulted in significant inhibition of 12-0-tetradecanoylphorbol-13-acetate (TPA)-caused induction of epidermal ODC, cyclooxygenase, and lipoxygenase activities and ODC mRNA expression in a does-dependent manner [10].
  • Transplacental carcinogenicity of cisplatin: initiation of skin tumors and induction of other preneoplastic and neoplastic lesions in SENCAR mice [11].
 

Chemical compound and disease context of Mice, Inbred SENCAR

 

Biological context of Mice, Inbred SENCAR

 

Anatomical context of Mice, Inbred SENCAR

 

Associations of Mice, Inbred SENCAR with chemical compounds

 

Gene context of Mice, Inbred SENCAR

  • Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10 [32].
  • Comparison of histologic changes in skin revealed that wa-1 mice exhibited only modest sustained epidermal hyperplasia after multiple treatments with TPA, similar in magnitude to that of C57BL/6 mice and significantly lower than that of SENCAR mice [33].
  • Dietary energy restriction inhibits ERK but not JNK or p38 activity in the epidermis of SENCAR mice [34].
  • Significant inhibition by the flavonoid antioxidant silymarin against 12-O-tetradecanoylphorbol 13-acetate-caused modulation of antioxidant and inflammatory enzymes, and cyclooxygenase 2 and interleukin-1alpha expression in SENCAR mouse epidermis: implications in the prevention of stage I tumor promotion [35].
  • In the present study, we used monospecific keratin antibodies to show the expression and distribution of keratins in SENCAR mouse vaginal epithelium in different stages of the estral cycle and in ovariectomized animals [36].
 

Analytical, diagnostic and therapeutic context of Mice, Inbred SENCAR

References

  1. Protection against malignant conversion of chemically induced benign skin papillomas to squamous cell carcinomas in SENCAR mice by a polyphenolic fraction isolated from green tea. Katiyar, S.K., Agarwal, R., Mukhtar, H. Cancer Res. (1993) [Pubmed]
  2. Murine epidermal xanthine oxidase activity: correlation with degree of hyperplasia induced by tumor promoters. Pence, B.C., Reiners, J.J. Cancer Res. (1987) [Pubmed]
  3. Inhibition of tumor promoter-mediated processes in mouse skin and bovine lens by caffeic acid phenethyl ester. Frenkel, K., Wei, H., Bhimani, R., Ye, J., Zadunaisky, J.A., Huang, M.T., Ferraro, T., Conney, A.H., Grunberger, D. Cancer Res. (1993) [Pubmed]
  4. Carcinogenic effects of acrylamide in Sencar and A/J mice. Bull, R.J., Robinson, M., Laurie, R.D., Stoner, G.D., Greisiger, E., Meier, J.R., Stober, J. Cancer Res. (1984) [Pubmed]
  5. Ovariectomy increases squamous metaplasia of the uterine horns and survival of SENCAR mice fed a vitamin A-deficient diet. Ponnamperuma, R.M., Kirchhof, S.M., Trifiletti, L., De Luca, L.M. Am. J. Clin. Nutr. (1999) [Pubmed]
  6. Effect of low dietary calcium on bone metabolism in the SENCAR mouse. Murray, E.J., Murray, S.S., Grisanti, M., Duarte, M.E., Urist, M.R. J. Orthop. Res. (1997) [Pubmed]
  7. Skin tumor promotion by phorbol esters is a two-stage process. Fürstenberger, G., Berry, D.L., Sorg, B., Marks, F. Proc. Natl. Acad. Sci. U.S.A. (1981) [Pubmed]
  8. Studies on mechanism of action of anti-tumor-promoting agents: their specificity in two-stage promotion. Slaga, T.J., Klein-Szanto, A.J., Fischer, S.M., Weeks, C.E., Nelson, K., Major, S. Proc. Natl. Acad. Sci. U.S.A. (1980) [Pubmed]
  9. A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model. Lahiri-Chatterjee, M., Katiyar, S.K., Mohan, R.R., Agarwal, R. Cancer Res. (1999) [Pubmed]
  10. Inhibition of tumor promotion in SENCAR mouse skin by ethanol extract of Zingiber officinale rhizome. Katiyar, S.K., Agarwal, R., Mukhtar, H. Cancer Res. (1996) [Pubmed]
  11. Transplacental carcinogenicity of cisplatin: initiation of skin tumors and induction of other preneoplastic and neoplastic lesions in SENCAR mice. Diwan, B.A., Anderson, L.M., Rehm, S., Rice, J.M. Cancer Res. (1993) [Pubmed]
  12. Elevated expression and point mutation of the Ha-ras proto-oncogene in mouse skin tumors promoted by benzoyl peroxide and other promoting agents. Pelling, J.C., Fischer, S.M., Neades, R., Strawhecker, J., Schweickert, L. Carcinogenesis (1987) [Pubmed]
  13. Regression and progression characteristics of papillomas induced by chrysarobin in SENCAR mice. Battalora, M.S., Conti, C.J., Aldaz, C.M., Slaga, T.J., Johnston, D.A., DiGiovanni, J. Carcinogenesis (1996) [Pubmed]
  14. Differential effects of dietary beta-carotene on papilloma and carcinoma formation induced by an initiation-promotion protocol in SENCAR mouse skin. Chen, L.C., Sly, L., Jones, C.S., Tarone, R., De Luca, L.M. Carcinogenesis (1993) [Pubmed]
  15. Mechanism of mouse skin tumor promotion by n-dodecane. Baxter, C.S., Miller, M.L. Carcinogenesis (1987) [Pubmed]
  16. Benzoyl peroxide activation of protein kinase C activity in epidermal cell membranes. Donnelly, T.E., Pelling, J.C., Anderson, C.L., Dalbey, D. Carcinogenesis (1987) [Pubmed]
  17. Deregulated expression of cell-cycle proteins during premalignant progression in SENCAR mouse skin. Rodriguez-Puebla, M.L., LaCava, M., Gimenez-Conti, I.B., Johnson, D.G., Conti, C.J. Oncogene (1998) [Pubmed]
  18. Inhibition of pro-inflammatory cytokine gene expression and papilloma growth during murine multistage carcinogenesis by pentoxifylline. Robertson, F.M., Ross, M.S., Tober, K.L., Long, B.W., Oberyszyn, T.M. Carcinogenesis (1996) [Pubmed]
  19. Gross and microscopic lesions in the female SENCAR mouse skin and lung in tumor initiation and promotion studies. Knutsen, G.L., Kovatch, R.M., Robinson, M. Environ. Health Perspect. (1986) [Pubmed]
  20. Strain-dependent differences in vertebral bone mass, serum osteocalcin, and calcitonin in calcium-replete and -deficient mice. Murray, E.J., Song, M.K., Laird, E.C., Murray, S.S. Proc. Soc. Exp. Biol. Med. (1993) [Pubmed]
  21. Atypical association of H1 and H2 histamine receptors with signal transduction pathways during multistage mouse skin carcinogenesis. Fitzsimons, C., Molinari, B., Duran, H., Palmieri, M., Davio, C., Cricco, G., Bergoc, R., Rivera, E. Inflamm. Res. (1997) [Pubmed]
  22. Enhanced release of hydrogen peroxide and metabolites of arachidonic acid by macrophages from SENCAR mice following stimulation with phorbol esters. Lewis, J.G., Adams, D.O. Cancer Res. (1986) [Pubmed]
  23. Induction of pyrimidine dimers and unscheduled DNA synthesis in cultured mouse epithelial cells exposed to 254-nm- and u.v.-B radiation. Yotti, L.P., Ley, R.D. Carcinogenesis (1983) [Pubmed]
  24. Sensitivity to tumor promotion of SENCAR and C57BL/6J mice correlates with oxidative events and DNA damage. Wei, L., Wei, H., Frenkel, K. Carcinogenesis (1993) [Pubmed]
  25. Analysis of v-Ha-ras and v-fos oncogene transduction into a mouse epidermal cell line with "initiated" phenotype in culture but normal skin phenotype in vivo. Ueda, M., Kawamura, H., Sutter, C., Glick, A., Yuspa, S.H., Strickland, J.E. Mol. Carcinog. (1995) [Pubmed]
  26. Characterization of covalently modified deoxyribonucleosides formed from dibenz[a,j]anthracene in primary cultures of mouse keratinocytes. Nair, R.V., Gill, R.D., Nettikumara, A.N., Baer-Dubowska, W., Cortez, C., Harvey, R.G., DiGiovanni, J. Chem. Res. Toxicol. (1991) [Pubmed]
  27. Alterations in epidermal polyamine levels and DNA synthesis following topical treatment with chrysarobin in SENCAR mice. Kruszewski, F.H., DiGiovanni, J. Cancer Res. (1988) [Pubmed]
  28. Inhibition of both stage I and stage II mouse skin tumour promotion by retinoic acid and the dependence of inhibition of tumor promotion on the duration of retinoic acid treatment. Verma, A.K. Cancer Res. (1987) [Pubmed]
  29. Mechanism of mouse skin tumor promotion by chrysarobin. DiGiovanni, J., Decina, P.C., Prichett, W.P., Cantor, J., Aalfs, K.K., Coombs, M.M. Cancer Res. (1985) [Pubmed]
  30. Terminal differentiation-resistant epidermal cells in mice undergoing two-stage carcinogenesis. Miller, D.R., Viaje, A., Aldaz, C.M., Conti, C.J., Slaga, T.J. Cancer Res. (1987) [Pubmed]
  31. Effect of dietary tannic acid on epidermal, lung, and forestomach polycyclic aromatic hydrocarbon metabolism and tumorigenicity in Sencar mice. Athar, M., Khan, W.A., Mukhtar, H. Cancer Res. (1989) [Pubmed]
  32. Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10. Sundberg, J.P., Erickson, A.A., Roop, D.R., Binder, R.L. Cancer Res. (1994) [Pubmed]
  33. Analysis of the ability of 12-O-tetradecanoylphorbol-13-acetate to induce epidermal hyperplasia, transforming growth factor-alpha, and skin tumor promotion in wa-1 mice. Kiguchi, K., Beltrán, L., Dubowski, A., DiGiovanni, J. J. Invest. Dermatol. (1997) [Pubmed]
  34. Dietary energy restriction inhibits ERK but not JNK or p38 activity in the epidermis of SENCAR mice. Liu, Y., Duysen, E., Yaktine, A.L., Au, A., Wang, W., Birt, D.F. Carcinogenesis (2001) [Pubmed]
  35. Significant inhibition by the flavonoid antioxidant silymarin against 12-O-tetradecanoylphorbol 13-acetate-caused modulation of antioxidant and inflammatory enzymes, and cyclooxygenase 2 and interleukin-1alpha expression in SENCAR mouse epidermis: implications in the prevention of stage I tumor promotion. Zhao, J., Sharma, Y., Agarwal, R. Mol. Carcinog. (1999) [Pubmed]
  36. Expression of keratins in mouse vaginal epithelium. Gimenez-Conti, I.B., Lynch, M., Roop, D., Bhowmik, S., Majeski, P., Conti, C.J. Differentiation (1994) [Pubmed]
  37. Induction of terminal differentiation-resistant epidermal cells in mouse skin and in papillomas by different initiators during two-stage carcinogenesis. Miller, D.R., Viaje, A., Rotstein, J., Aldaz, C.M., Conti, C.J., Slaga, T.J. Cancer Res. (1989) [Pubmed]
  38. Oral administration of the citrus coumarin, isopimpinellin, blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene in SENCAR mice. Kleiner, H.E., Vulimiri, S.V., Starost, M.F., Reed, M.J., DiGiovanni, J. Carcinogenesis (2002) [Pubmed]
  39. Inhibition of 12-O-tetradecanoylphorbol-13-acetate and other skin tumor-promoter-caused induction of epidermal interleukin-1 alpha mRNA and protein expression in SENCAR mice by green tea polyphenols. Katiyar, S.K., Rupp, C.O., Korman, N.J., Agarwal, R., Mukhtar, H. J. Invest. Dermatol. (1995) [Pubmed]
  40. Activation of the epidermal growth factor receptor by skin tumor promoters and in skin tumors from SENCAR mice. Xian, W., Kiguchi, K., Imamoto, A., Rupp, T., Zilberstein, A., DiGiovanni, J. Cell Growth Differ. (1995) [Pubmed]
  41. Evaluation of properties of apigenin and [G-3H]apigenin and analytic method development. Li, B., Robinson, D.H., Birt, D.F. Journal of pharmaceutical sciences. (1997) [Pubmed]
 
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