Disease relevance of Pulmonary Valve Insufficiency

• Alcohol abuse and malnutrition could not be implicated in the pathogenesis of injury; rather it appeared that advancing age with chronic renal, cardiac and pulmonary insufficiency contributed to acetaminophen toxicity in this patient [1].
• METHODS: In 19 patients with CPTE and 16 patients with PPH, we estimated PA systolic pressure and diastolic pressure from the velocities of tricuspid regurgitation and pulmonary regurgitation, respectively [2].
• Cystic fibrosis (CF) is characterized in the lung by chronic purulent bronchitis culminating in pulmonary insufficiency [3].
• In addition, the following postoperative complications were independently associated with lack of daily rounds by an ICU physician: pulmonary insufficiency (odds ratio [OR], 4.0; CI, 1.4-11.0), renal failure (OR, 6.3; CI, 1.4-28.7), aspiration (OR, 1.7; CI, 1.0-2.8), and reintubation (OR, 2.8; CI, 1.5-5.2) [4].
• CONCLUSIONS: Severe right ventricular dilatation and pulmonary regurgitation secondary to outflow tract repair in tetralogy of Fallot are frequently occurring sequelae developing slowly over time [5].

High impact information on Pulmonary Valve Insufficiency

• Of these six, the major indication for reoperation was right ventricular outflow tract obstruction in four, tricuspid and pulmonary regurgitation in one, and a residual ventricular septal defect and patent shunt in one [6].
• ADA-deficient mice develop a combined immunodeficiency as well as severe pulmonary insufficiency [7].
• Effect of alpha and beta adrenergic blockade on epinephrine induced pulmonary insufficiency [8].
• Inositol, free fatty acids, vitamin E and vitamin A are proposed as nutrients for which infants at risk of chronic pulmonary insufficiency may have special requirements [9].
• Chronic pulmonary insufficiency of prematurity (CPIP) [10].

Chemical compound and disease context of Pulmonary Valve Insufficiency

• In O2, there was pulmonary insufficiency the first 3 days, followed by recovery, and later hypercarbia and decreased arterial PO2 [11].
• Pulmonary insufficiency induced by oleic acid in the sheep: a model for investigation of extracorporeal oxygenation [12].
• Methylprednisolone in posttraumatic pulmonary insufficiency [13].
• Pulmonary insufficiency from high dose Ara-C varies in severity and may be fatal [14].
• No significant differences were found in R, MWT og B between chronic pulmonary insufficiency patients and normal controls [15].

Biological context of Pulmonary Valve Insufficiency

• Thus significant tricuspid regurgitation was associated with high right ventricular systolic pressure, high right ventricular end-diastolic pressure, and significant pulmonary regurgitation and residual ventricular septal defect, which increased the right ventricular end-diastolic volume [16].
• Hypoxic pulmonary vasoconstriction in post-traumatic pulmonary insufficiency. The effect of methylprednisolone [17].
• Deficit in a humoral opsonic glycoprotein (alpha 2 SB glycoprotein) important for reticuloendothelial phagocytosis is described in various types of traumatic injuries, and the role of RES in relation to pulmonary insufficiency is finally summarized [18].
• Cystic fibrosis (CF) is a genetic disorder that leads to a defect in chloride ion transport and results in pancreatic and pulmonary insufficiency [19].

Anatomical context of Pulmonary Valve Insufficiency

• Underlying heart diseases were old myocardial infarction (n = 2), postoperative tetralogy of Fallot (n = 1) or double outlet of the right ventricle (n = 1), dilated cardiomyopathy (n = 1), and pulmonary regurgitation of unknown cause (n = 1) [20].
• METHODS AND RESULTS: Under x-ray fluoroscopic guidance, endovascular nitinol stents were placed across the pulmonary valve in 6 young pigs to induce pulmonary regurgitation [21].
• The main cardiac lesions were mitral valve prolapse (60.8%), atrial septal defect (8.6%), ventricle septal defect (6.5%) and aortic regurgitation (4.3%) and 2.1% each of tricuspid regurgitation, pulmonary regurgitation, Ebstein's anomaly, coarctation of aorta, patent ductus arteriosus, and Eisenmenger's syndrome [22].

Gene context of Pulmonary Valve Insufficiency

• ADA-deficient mice also exhibited severe pulmonary insufficiency, bone abnormalities, and kidney pathogenesis [23].
• Pulmonary regurgitation end-diastolic gradient is a Doppler marker of cardiac status: data from the Heart and Soul Study [24].
• Elevated levels of von Willebrand Factor Antigen (vWF:Ag) may occur in the presence of endothelial injury, a component in the pathology of acute pulmonary insufficiency [25].
• Persistent fetal circulation (PFC) causes severe pulmonary insufficiency in patients who have demonstrated adequate lung function following diaphragmatic hernia repair [26].
• During the follow-up, reoperation was necessary for repair of residual ventricular septal defect and pulmonary regurgitation in two patients, and closure of an atrial septal defect and alteration to left atrioventricular valvar regurgitation in one patient [27].

Analytical, diagnostic and therapeutic context of Pulmonary Valve Insufficiency

• Cardiac catheterization and angiography revealed moderate pulmonary insufficiency in all patients, a residual pressure gradient in the right ventricular outflow tract in 7, and a residual ventricular septal defect in 2 patients [28].
• Therefore, gallium scans can be utilized for the early diagnosis of drug-induced pulmonary reactions, leading to withdrawal of the drug and preventing the irreversible and potentially serious complication of pulmonary insufficiency [29].
• Incremental doses of vitamin B1 were injected into patients with myocardial and pulmonary insufficiency treated in the post-operative period in the ICU (intensive care unit) after repairment of abdominal aneurysm [30].
• Complications associated with molar pregnancy usually are a result of suction curettage and include pulmonary insufficiency syndrome, choriocarcinoma, hyperthyroidism, theca lutein cysts, and disseminated intravascular coagulation [31].

References