The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Combined Modality Therapy

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Combined Modality Therapy


Psychiatry related information on Combined Modality Therapy


High impact information on Combined Modality Therapy


Chemical compound and disease context of Combined Modality Therapy


Biological context of Combined Modality Therapy


Anatomical context of Combined Modality Therapy


Associations of Combined Modality Therapy with chemical compounds

  • Seven of these patients received combined modality therapy in which prednisone was given with their MOPP [26].
  • The major recent development that is likely to influence the future of combined modality therapy for this disease is the advent of multiple new chemotherapeutic agents, such as the taxanes, gemcitabine, vinorelbine, and the topoisomerase-I inhibitors, which have activity in stage IV disease [27].
  • UFT plus oral leucovorin calcium (Orzel) and radiation in combined modality therapy: a comprehensive review [28].
  • In Phase II non-surgical trials preoperative treatment consisting of cisplatin containing combination regimens given simultaneously with thoracic radiation have shown that this type of combined modality therapy is feasible and that the rates of resectability appear to be higher than would be expected with surgery alone [29].
  • The combination of paclitaxel and carboplatin is active and well tolerated in patients with advanced NSCLC, and paclitaxel-based combined-modality therapy produced a high rate of complete and partial responses and encouraging survival data [30].

Gene context of Combined Modality Therapy


Analytical, diagnostic and therapeutic context of Combined Modality Therapy


  1. Phase I trial of combined-modality therapy for localized esophageal cancer: escalating doses of continuous-infusion paclitaxel with cisplatin and concurrent radiation therapy. Brenner, B., Ilson, D.H., Minsky, B.D., Bains, M.S., Tong, W., Gonen, M., Kelsen, D.P. J. Clin. Oncol. (2004) [Pubmed]
  2. Phase III randomized intergroup trial of subtotal lymphoid irradiation versus doxorubicin, vinblastine, and subtotal lymphoid irradiation for stage IA to IIA Hodgkin's disease. Press, O.W., LeBlanc, M., Lichter, A.S., Grogan, T.M., Unger, J.M., Wasserman, T.H., Gaynor, E.R., Peterson, B.A., Miller, T.P., Fisher, R.I. J. Clin. Oncol. (2001) [Pubmed]
  3. Long-term follow-up for locally advanced and inflammatory breast cancer patients treated with multimodality therapy. Low, J.A., Berman, A.W., Steinberg, S.M., Danforth, D.N., Lippman, M.E., Swain, S.M. J. Clin. Oncol. (2004) [Pubmed]
  4. The epidermal growth factor receptor pathway mediates resistance to sequential administration of radiation and chemotherapy in primary human glioblastoma cells in a RAS-dependent manner. Chakravarti, A., Chakladar, A., Delaney, M.A., Latham, D.E., Loeffler, J.S. Cancer Res. (2002) [Pubmed]
  5. Prognostic significance of cyclin D1 in esophageal squamous cell carcinoma patients treated with surgery alone or combined therapy modalities. Sarbia, M., Stahl, M., Fink, U., Heep, H., Dutkowski, P., Willers, R., Seeber, S., Gabbert, H.E. Int. J. Cancer (1999) [Pubmed]
  6. Case study: fluoxetine in the multimodal treatment of a preschool child with selective mutism. Wright, H.H., Cuccaro, M.L., Leonhardt, T.V., Kendall, D.F., Anderson, J.H. Journal of the American Academy of Child and Adolescent Psychiatry. (1995) [Pubmed]
  7. Late genitourinary and gastrointestinal toxicity after magnetic resonance image-guided prostate brachytherapy with or without neoadjuvant external beam radiation therapy. Albert, M., Tempany, C.M., Schultz, D., Chen, M.H., Cormack, R.A., Kumar, S., Hurwitz, M.D., Beard, C., Tuncali, K., O'Leary, M., Topulos, G.P., Valentine, K., Lopes, L., Kanan, A., Kacher, D., Rosato, J., Kooy, H., Jolesz, F., Carr-Locke, D.L., Richie, J.P., D'Amico, A.V. Cancer (2003) [Pubmed]
  8. Improvement in psychological functioning among drug abusers: inpatient treatment compared to outpatient methadone maintenance. Craig, R.J., Olson, R., Shalton, G. Journal of substance abuse treatment. (1990) [Pubmed]
  9. Chemical aversion therapy in the treatment of cocaine dependence as part of a multimodal treatment program: treatment outcome. Frawley, P.J., Smith, J.W. Journal of substance abuse treatment. (1990) [Pubmed]
  10. Commentary on the multimodal treatment study of children with ADHD. Barkley, R.A. Journal of abnormal child psychology. (2000) [Pubmed]
  11. Chemoradiotherapy of locally advanced esophageal cancer: long-term follow-up of a prospective randomized trial (RTOG 85-01). Radiation Therapy Oncology Group. Cooper, J.S., Guo, M.D., Herskovic, A., Macdonald, J.S., Martenson, J.A., Al-Sarraf, M., Byhardt, R., Russell, A.H., Beitler, J.J., Spencer, S., Asbell, S.O., Graham, M.V., Leichman, L.L. JAMA (1999) [Pubmed]
  12. A multidisciplinary approach to therapy for unresectable malignant thymoma. Shin, D.M., Walsh, G.L., Komaki, R., Putnam, J.B., Nesbitt, J., Ro, J.Y., Shin, H.J., Ki, K.H., Wimberly, A., Pisters, K.M., Schrump, D., Gregurich, M.A., Cox, J.D., Roth, J.A., Hong, W.K. Ann. Intern. Med. (1998) [Pubmed]
  13. Thoracic radiation therapy alone compared with combined chemoradiotherapy for locally unresectable non-small cell lung cancer. A randomized, phase III trial. Morton, R.F., Jett, J.R., McGinnis, W.L., Earle, J.D., Therneau, T.M., Krook, J.E., Elliott, T.E., Mailliard, J.A., Nelimark, R.A., Maksymiuk, A.W. Ann. Intern. Med. (1991) [Pubmed]
  14. Telomerase-dependent virotherapy overcomes resistance of hepatocellular carcinomas against chemotherapy and tumor necrosis factor-related apoptosis-inducing ligand by elimination of Mcl-1. Wirth, T., Kühnel, F., Fleischmann-Mundt, B., Woller, N., Djojosubroto, M., Rudolph, K.L., Manns, M., Zender, L., Kubicka, S. Cancer Res. (2005) [Pubmed]
  15. Importance of timing for thoracic irradiation in the combined modality treatment of limited-stage small-cell lung cancer. The National Cancer Institute of Canada Clinical Trials Group. Murray, N., Coy, P., Pater, J.L., Hodson, I., Arnold, A., Zee, B.C., Payne, D., Kostashuk, E.C., Evans, W.K., Dixon, P. J. Clin. Oncol. (1993) [Pubmed]
  16. Incorporation of paclitaxel and carboplatin in combined-modality therapy for locally advanced non-small cell lung cancer. Belani, C.P. Semin. Oncol. (1999) [Pubmed]
  17. Oxaliplatin-based combined-modality therapy for rectal cancer. Minsky, B.D. Semin. Oncol. (2003) [Pubmed]
  18. Is intensity-modulated radiotherapy better than conventional radiation treatment and three-dimensional conformal radiotherapy for mediastinal masses in patients with Hodgkin's disease, and is there a role for beam orientation optimization and dose constraints assigned to virtual volumes? Girinsky, T., Pichenot, C., Beaudre, A., Ghalibafian, M., Lefkopoulos, D. Int. J. Radiat. Oncol. Biol. Phys. (2006) [Pubmed]
  19. The combined modality therapy of diffuse histology non-Hodgkin's lymphoma with cyclophosphamide, adriamycin, vincristine, prednisone (CHOP) and total body irradiation. Weick, J.K., Antunez, A., Kraus, T.A., Fabian, C.J., Dixon, D. Int. J. Radiat. Oncol. Biol. Phys. (1983) [Pubmed]
  20. Curative radiotherapy following chemotherapy for invasive bladder carcinoma (a preliminary report). Farah, R., Chodak, G.W., Vogelzang, N.J., Awan, A.M., Quiet, C.A., Moormeier, J., Schoenberg, H., Weichselbaum, R.R. Int. J. Radiat. Oncol. Biol. Phys. (1991) [Pubmed]
  21. The prognostic significance of genetic polymorphisms (Methylenetetrahydrofolate Reductase C677T, Methionine Synthase A2756G, Thymidilate Synthase tandem repeat polymorphism) in multimodally treated oesophageal squamous cell carcinoma. Sarbia, M., Stahl, M., von Weyhern, C., Weirich, G., Pühringer-Oppermann, F. Br. J. Cancer (2006) [Pubmed]
  22. Pharmacokinetics of cisplatin in patients receiving interleukin-2-containing treatment regimens. Gandara, D.R., Perez, E.A., Denham, A., Wiebe, V.J., DeGregorio, M.W. Cancer Chemother. Pharmacol. (1989) [Pubmed]
  23. Pilot study of local hyperthermia, radiation therapy, etanidazole, and cisplatin for advanced superficial tumours. Bornstein, B.A., Herman, T.S., Hansen, J.L., Buswell, L., Zouranjian, P.S., Fraser, S.M., Teicher, B.A., Svensson, G.K., Coleman, C.N. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. (1995) [Pubmed]
  24. Academy of eating disorders international conference. Brewerton, T.D. Expert opinion on investigational drugs. (2004) [Pubmed]
  25. Concurrent chemotherapy (5-fluorouracil and cisplatin) and radiation therapy followed by surgery for T4 squamous cell carcinoma of the esophagus. Yano, M., Tsujinaka, T., Shiozaki, H., Inoue, M., Doki, Y., Yamamoto, M., Tanaka, E., Inoue, T., Monden, M. Journal of surgical oncology. (1999) [Pubmed]
  26. Unusual thoracic radiographic findings in children treated for Hodgkin's disease. Jochelson, M.S., Tarbell, N.J., Weinstein, H.J. J. Clin. Oncol. (1986) [Pubmed]
  27. Combined modality therapy of lung cancer. Livingston, R.B. Clin. Cancer Res. (1997) [Pubmed]
  28. UFT plus oral leucovorin calcium (Orzel) and radiation in combined modality therapy: a comprehensive review. Minsky, B.D. Int. J. Cancer (2001) [Pubmed]
  29. Radiation and simultaneous cisplatin in non-small cell lung cancer. Bonomi, P. Int. J. Radiat. Oncol. Biol. Phys. (1993) [Pubmed]
  30. One-hour paclitaxel in the treatment of non-small cell lung cancer. Hainsworth, J.D., Greco, F.A. Semin. Oncol. (1996) [Pubmed]
  31. Neuroendocrine gastrointestinal tumors--a condensed overview of diagnosis and treatment. Oberg, K. Ann. Oncol. (1999) [Pubmed]
  32. Cyclooxygenase-2 inhibition in colorectal cancer: boom or bust? Sanborn, R., Blanke, C.D. Semin. Oncol. (2005) [Pubmed]
  33. Molecular strategies targeting the host component of cancer to enhance tumor response to radiation therapy. Kim, D.W., Huamani, J., Fu, A., Hallahan, D.E. Int. J. Radiat. Oncol. Biol. Phys. (2006) [Pubmed]
  34. Combined modality therapy of A431 human epidermoid cancer using anti-EGFr antibody C225 and radiation. Saleh, M.N., Raisch, K.P., Stackhouse, M.A., Grizzle, W.E., Bonner, J.A., Mayo, M.S., Kim, H.G., Meredith, R.F., Wheeler, R.H., Buchsbaum, D.J. Cancer Biother. Radiopharm. (1999) [Pubmed]
  35. p53 and p21 Expression levels predict organ preservation and survival in invasive bladder carcinoma treated with a combined-modality approach. Garcia del Muro, X., Condom, E., Vigués, F., Castellsagué, X., Figueras, A., Muñoz, J., Solá, J., Soler, T., Capellà, G., Germà, J.R. Cancer (2004) [Pubmed]
  36. Enhancement of radiation-induced cell kill by platinum complexes (carboplatin and iproplatin) in V79 cells. O'Hara, J.A., Douple, E.B., Richmond, R.C. Int. J. Radiat. Oncol. Biol. Phys. (1986) [Pubmed]
  37. Improvement of combined modality therapy with cisplatin and radiation using electroporation of tumors. Sersa, G., Kranjc, S., Cemazar, M. Int. J. Radiat. Oncol. Biol. Phys. (2000) [Pubmed]
  38. Treatment selection for stage IIIA Hodgkin's disease patients. Prosnitz, L.R., Cooper, D., Cox, E.B., Kapp, D.S., Farber, L.R. Int. J. Radiat. Oncol. Biol. Phys. (1985) [Pubmed]
  39. Early cervical adenocarcinoma: selection criteria for radical surgery. Schorge, J.O., Lee, K.R., Lee, S.J., Flynn, C.E., Goodman, A., Sheets, E.E. Obstetrics and gynecology. (1999) [Pubmed]
  40. Chlorhexidine lavage in the treatment of experimental intra-abdominal infection. Bondar, V.M., Rago, C., Cottone, F.J., Wilkerson, D.K., Riggs, J. Archives of surgery (Chicago, Ill. : 1960) (2000) [Pubmed]
WikiGenes - Universities