The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Portacaval Shunt, Surgical

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Portacaval Shunt, Surgical


High impact information on Portacaval Shunt, Surgical


Chemical compound and disease context of Portacaval Shunt, Surgical


Biological context of Portacaval Shunt, Surgical


Anatomical context of Portacaval Shunt, Surgical


Associations of Portacaval Shunt, Surgical with chemical compounds

  • The turnover of 125I-labeled low density lipoprotein (LDL) and the total body balance of cholestrol were studied in a 6-yr-old girl with the homozygous form of familial hypercholesterolemia (FH) before and after the surgical creation of an end-to-side portacaval shunt [9].
  • Fourteen days after an end-to-side portacaval anastomosis the galactose elimination capacity and the plasma clearance of indocyanine green were reduced in proportion to the approximately 50% loss in liver mass [22].
  • Six weeks after portacaval shunt, mean peak levels of plasma tyrosine, achieved at 5 hr after dose administration, were 450 as compared to 85 mumoles per liter obtained in preshunted dogs [14].
  • The biliary transport maximum for sulfobromophthalein, on the other hand, decreased by almost 70% from 153 to 52 nmoles per min per min per 100 g after portacaval anastomosis [22].
  • The data are consistent with the hypothesis of an impaired release of vitamin A from the liver in rats with portacaval shunts, an impairment that could be due to liver zinc deficiency [23].

Gene context of Portacaval Shunt, Surgical


Analytical, diagnostic and therapeutic context of Portacaval Shunt, Surgical


  1. Enhanced hyperplasia of gastric enterochromaffinlike cells in response to omeprazole-evoked hypergastrinemia in rats with portacaval shunts. An immunocytochemical and chemical study. Axelson, J., Ekelund, M., Sundler, F., Håkanson, R. Gastroenterology (1990) [Pubmed]
  2. Increased density of brain histamine H(1) receptors in rats with portacaval anastomosis and in cirrhotic patients with chronic hepatic encephalopathy. Lozeva, V., Tuomisto, L., Sola, D., Plumed, C., Hippeläinen, M., Butterworth, R. Hepatology (2001) [Pubmed]
  3. Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts. Erceg, S., Monfort, P., Hernández-Viadel, M., Rodrigo, R., Montoliu, C., Felipo, V. Hepatology (2005) [Pubmed]
  4. Indomethacin prevents the development of experimental ammonia-induced brain edema in rats after portacaval anastomosis. Chung, C., Gottstein, J., Blei, A.T. Hepatology (2001) [Pubmed]
  5. In vivo studies of GABAergic effects in experimental hepatic encephalopathy. Rzepczynski, D., Zieve, L., Lindblad, S., LaFontaine, D. Hepatology (1986) [Pubmed]
  6. Failure to produce hepatic hyperplastic nodules in rats by portacaval anastomosis and testosterone. Wanless, I.R., Gledhill, R.W. Nature (1979) [Pubmed]
  7. Increased sensitivity of gastric acid secretion to gastrin in cirrhotic patients with portacaval shunt. Lenz, H.J., Struck, T., Greten, H., Koss, M.A., Eysselein, V.E., Walsh, J.H., Isenberg, J.I. J. Clin. Invest. (1987) [Pubmed]
  8. Evidence for central hypertyraminemia in hepatic encephalopathy. Faraj, B.A., Camp, V.M., Ansley, J.D., Scott, J., Ali, F.M., Malveaux, E.J. J. Clin. Invest. (1981) [Pubmed]
  9. Reduction in cholesterol and low density lipoprotein synthesis after portacaval shunt surgery in a patient with homozygous familial hypercholesterolemia. Bilheimer, D.W., Goldstein, J.L., Grundy, S.M., Brown, M.S. J. Clin. Invest. (1975) [Pubmed]
  10. Cerebral blood flow and the development of ammonia-induced brain edema in rats after portacaval anastomosis. Master, S., Gottstein, J., Blei, A.T. Hepatology (1999) [Pubmed]
  11. Prognostic value of indocyanine green and lidocaine kinetics for survival and chronic hepatic encephalopathy in cirrhotic patients following elective end-to-side portacaval shunt. Pomier-Layrargues, G., Huet, P.M., Infante-Rivard, C., Villeneuve, J.P., Marleau, D., Duguay, L., Tanguay, S., Lavoie, P. Hepatology (1988) [Pubmed]
  12. Altered control of growth hormone secretion in patients with cirrhosis of the liver. Muggeo, M., Tiengo, A., Fedele, D., Crepaldi, G. Arch. Intern. Med. (1979) [Pubmed]
  13. Local cerebral glucose metabolism in rats with chronic portacaval shunts. Cruz, N.F., Duffy, T.E. J. Cereb. Blood Flow Metab. (1983) [Pubmed]
  14. Decarboxylation to tyramine: an important route of tyrosine metabolism in dogs with experimental hepatic encephalopathy. Faraj, B.A., Ali, F.M., Ansley, J.D., Malveaux, E.J. Gastroenterology (1978) [Pubmed]
  15. Effects of insulin, glucagon, and insuling/glucagon infusions on liver morphology and cell division after complete portacaval shunt in dogs. Starzl, T.E., Watanabe, K., Porter, K.A., Putnam, C.W. Lancet (1976) [Pubmed]
  16. Cholesterol homeostasis in the rat with a portacaval anastomosis. Proia, A., McNamara, D.J., Edwards, K.D., Ahrens, E.H. Proc. Natl. Acad. Sci. U.S.A. (1979) [Pubmed]
  17. Glutamine, myo-inositol, and organic brain osmolytes after portocaval anastomosis in the rat: implications for ammonia-induced brain edema. Cordoba, J., Gottstein, J., Blei, A.T. Hepatology (1996) [Pubmed]
  18. The clearance rate of chylomicron retinyl ester from plasma can be used to distinguish rats with cirrhosis from those with portacaval shunt. Kasai, T., Moriwaki, H., Okuno, M., Numaguchi, S., Murakami, N., Seishima, M., Ohnishi, H., Shidoji, Y., Muto, Y. Hepatology (1993) [Pubmed]
  19. Intrasplenic hepatocyte transplantation in rats with experimental liver injury: morphological and morphometric studies. Hillan, K.J., Burt, A.D., George, W.D., MacSween, R.N., Griffiths, M.R., Bradley, J.A. J. Pathol. (1989) [Pubmed]
  20. Heterogeneous astroglial response in the rat spinal cord to long-term portacaval shunt: an immunohistochemical study. Bodega, G., Suárez, I., Arilla, E., Rubio, M., Fernández, B. Glia (1991) [Pubmed]
  21. In vivo hydroxylation of 3H-acetanilide--evaluation of a new radiospirometric method in the rat. Toutoungi, M., Bieri, H.U., Huguenin, P., Karlaganis, G., Zeng, T.T., Bircher, J. Biochem. Pharmacol. (1983) [Pubmed]
  22. Hepatic functional deterioration after portacaval shunt in the rat. Effects on sulfobromophthalein transport-maximum, indocyanine green clearance and galactose elimination capacity. Lauterburg, B.H., Sautter, V., Preisig, R., Bircher, J. Gastroenterology (1976) [Pubmed]
  23. Portacaval shunt as an experimental model of impaired hepatic release of vitamin A in liver disease. Schölmerich, J., Fabian, M., Tauber, R., Löhle, E., Köttgen, E., Grün, M., Wietholtz, H., Baumgartner, U., Gerok, W. Gastroenterology (1991) [Pubmed]
  24. Evidence for modulation of hepatic mass by estrogens and hepatic "feminization". Van Thiel, D.H., Stauber, R.E., Gavaler, J.S., Rosenblum, E. Hepatology (1990) [Pubmed]
  25. Pituitary and thyroid function before and after portacaval anastomosis in patients with normal livers. Kalk, W.J., Russel, D., Seftel, H.C., Van der Walt, L.A. J. Clin. Endocrinol. Metab. (1980) [Pubmed]
  26. Somatostatin cells in the oxyntic mucosa of hypo- or hypergastrinemic rats. Chen, D., Uribe, A., Håkanson, R., Sundler, F. Scand. J. Gastroenterol. (1992) [Pubmed]
  27. Hepatic and pulmonary clearance of exogenous vasoactive intestinal peptide in the rat. Humphrey, C.S., Murray, P., Ebeid, A.M., Fischer, J.E. Gastroenterology (1979) [Pubmed]
  28. Short-term administration of parenteral glucose-lipid mixtures improves protein kinetics in portacaval shunted rats. Pomposelli, J.J., Moldawer, L.L., Palombo, J.D., Babayan, V.K., Bistrian, B.R., Blackburn, G.L. Gastroenterology (1986) [Pubmed]
  29. Propoxyphene and norpropoxyphene plasma concentrations after oral propoxyphene in cirrhotic patients with and without surgically constructed portacaval shunt. Giacomini, K.M., Giacomini, J.C., Gibson, T.P., Levy, G. Clin. Pharmacol. Ther. (1980) [Pubmed]
  30. Selective loss of N-methyl-D-aspartate-sensitive L-[3H]glutamate binding sites in rat brain following portacaval anastomosis. Peterson, C., Giguere, J.F., Cotman, C.W., Butterworth, R.F. J. Neurochem. (1990) [Pubmed]
WikiGenes - Universities