The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Lexapro     (1S)-1-(3- dimethylaminopropyl)-1-(4...

Synonyms: Seroplex, Escitalopram, R-Citalopram, Lopac-C-7861, Tocris-1427, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Escitalopram


Psychiatry related information on Escitalopram


High impact information on Escitalopram


Chemical compound and disease context of Escitalopram


Biological context of Escitalopram


Anatomical context of Escitalopram


Associations of Escitalopram with other chemical compounds


Gene context of Escitalopram


Analytical, diagnostic and therapeutic context of Escitalopram


  1. Quetiapine-induced weight gain and escitalopram. Holzer, L., Paiva, G., Halfon, O. The American journal of psychiatry. (2005) [Pubmed]
  2. A case of hyponatremia associated with escitalopram. Nahshoni, E., Weizman, A., Shefet, D., Pik, N. The Journal of clinical psychiatry. (2004) [Pubmed]
  3. A 24-week randomized, double-blind, placebo-controlled study of escitalopram for the prevention of generalized social anxiety disorder. Montgomery, S.A., Nil, R., Dürr-Pal, N., Loft, H., Boulenger, J.P. The Journal of clinical psychiatry. (2005) [Pubmed]
  4. Combination therapy of lamotrigine and escitalopram may cause myoclonus. Rosenhagen, M.C., Schmidt, U., Weber, F., Steiger, A. Journal of clinical psychopharmacology. (2006) [Pubmed]
  5. A double-blind, randomized, placebo-controlled trial of escitalopram in the treatment of pediatric depression. Wagner, K.D., Jonas, J., Findling, R.L., Ventura, D., Saikali, K. Journal of the American Academy of Child and Adolescent Psychiatry. (2006) [Pubmed]
  6. Escitalopram and paroxetine in the treatment of generalised anxiety disorder: randomised, placebo-controlled, double-blind study. Baldwin, D.S., Huusom, A.K., Maehlum, E. The British journal of psychiatry : the journal of mental science. (2006) [Pubmed]
  7. Escitalopram in the treatment of panic disorder: a randomized, double-blind, placebo-controlled trial. Stahl, S.M., Gergel, I., Li, D. The Journal of clinical psychiatry. (2003) [Pubmed]
  8. An open trial of adjunctive escitalopram in bipolar depression. Fonseca, M., Soares, J.C., Hatch, J.P., Santin, A.P., Kapczinski, F. The Journal of clinical psychiatry. (2006) [Pubmed]
  9. Open-label trial of escitalopram in the treatment of posttraumatic stress disorder. Robert, S., Hamner, M.B., Ulmer, H.G., Lorberbaum, J.P., Durkalski, V.L. The Journal of clinical psychiatry (2006) [Pubmed]
  10. Actual driving performance and psychomotor function in healthy subjects after acute and subchronic treatment with escitalopram, mirtazapine, and placebo: a crossover trial. Wingen, M., Bothmer, J., Langer, S., Ramaekers, J.G. The Journal of clinical psychiatry. (2005) [Pubmed]
  11. Second-generation SSRIs: human monoamine transporter binding profile of escitalopram and R-fluoxetine. Owens, M.J., Knight, D.L., Nemeroff, C.B. Biol. Psychiatry (2001) [Pubmed]
  12. The clinical pharmacokinetics of escitalopram. Rao, N. Clinical pharmacokinetics (2007) [Pubmed]
  13. Escitalopram versus venlafaxine XR in the treatment of depression. Montgomery, S.A., Andersen, H.F. International clinical psychopharmacology. (2006) [Pubmed]
  14. Escitalopram treatment of trichotillomania. Gadde, K.M., Ryan Wagner, H., Connor, K.M., Foust, M.S. International clinical psychopharmacology (2007) [Pubmed]
  15. Oculogyric dystonic reaction to escitalopram with features of anaphylaxis including response to epinephrine. Patel, O.P., Simon, M.R. Int. Arch. Allergy Immunol. (2006) [Pubmed]
  16. A preliminary study of luteal phase versus symptom-onset dosing with escitalopram for premenstrual dysphoric disorder. Freeman, E.W., Sondheimer, S.J., Sammel, M.D., Ferdousi, T., Lin, H. The Journal of clinical psychiatry. (2005) [Pubmed]
  17. Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities. Sánchez, C., Bergqvist, P.B., Brennum, L.T., Gupta, S., Hogg, S., Larsen, A., Wiborg, O. Psychopharmacology (Berl.) (2003) [Pubmed]
  18. Transfer of escitalopram and its metabolite demethylescitalopram into breastmilk. Rampono, J., Hackett, L.P., Kristensen, J.H., Kohan, R., Page-Sharp, M., Ilett, K.F. British journal of clinical pharmacology. (2006) [Pubmed]
  19. Hippocampal cytogenesis correlates to escitalopram-mediated recovery in a chronic mild stress rat model of depression. Jayatissa, M.N., Bisgaard, C., Tingstr??m, A., Papp, M., Wiborg, O. Neuropsychopharmacology (2006) [Pubmed]
  20. Does rTMS hasten the response to escitalopram, sertraline, or venlafaxine in patients with major depressive disorder? A double-blind, randomized, sham-controlled trial. Rossini, D., Magri, L., Lucca, A., Giordani, S., Smeraldi, E., Zanardi, R. The Journal of clinical psychiatry. (2005) [Pubmed]
  21. In vivo imaging of serotonin transporter occupancy by means of SPECT and [(123)I]ADAM in healthy subjects administered different doses of escitalopram or citalopram. Klein, N., Sacher, J., Geiss-Granadia, T., Attarbaschi, T., Mossaheb, N., Lanzenberger, R., Pötzi, C., Holik, A., Spindelegger, C., Asenbaum, S., Dudczak, R., Tauscher, J., Kasper, S. Psychopharmacology (Berl.) (2006) [Pubmed]
  22. Allosteric modulation of the effect of escitalopram, paroxetine and fluoxetine: in-vitro and in-vivo studies. Mansari, M.E., Wiborg, O., Mnie-Filali, O., Benturquia, N., Sánchez, C., Haddjeri, N. Int. J. Neuropsychopharmacol. (2007) [Pubmed]
  23. Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram. von Moltke, L.L., Greenblatt, D.J., Giancarlo, G.M., Granda, B.W., Harmatz, J.S., Shader, R.I. Drug Metab. Dispos. (2001) [Pubmed]
  24. Comparison of the effects of citalopram and escitalopram on 5-Ht-mediated neuroendocrine responses. Nadeem, H.S., Attenburrow, M.J., Cowen, P.J. Neuropsychopharmacology (2004) [Pubmed]
  25. Comparison of duloxetine, escitalopram, and sertraline effects on cytochrome P450 2D6 function in healthy volunteers. Preskorn, S.H., Greenblatt, D.J., Flockhart, D., Luo, Y., Perloff, E.S., Harmatz, J.S., Baker, B., Klick-Davis, A., Desta, Z., Burt, T. Journal of clinical psychopharmacology (2007) [Pubmed]
  26. R-citalopram functionally antagonises escitalopram in vivo and in vitro: evidence for kinetic interaction at the serotonin transporter. Stórustovu, S., Sánchez, C., Pörzgen, P., Brennum, L.T., Larsen, A.K., Pulis, M., Ebert, B. Br. J. Pharmacol. (2004) [Pubmed]
  27. Early life trauma decreases glucocorticoid receptors in rat dentate gyrus upon adult re-stress: reversal by escitalopram. Uys, J.D., Muller, C.J., Marais, L., Harvey, B.H., Stein, D.J., Daniels, W.M. Neuroscience (2006) [Pubmed]
  28. Noradrenergic augmentation of escitalopram response by risperidone: electrophysiologic studies in the rat brain. Dremencov, E., El Mansari, M., Blier, P. Biol. Psychiatry (2007) [Pubmed]
  29. The pharmacokinetics of escitalopram in patients with hepatic impairment. Areberg, J., Christophersen, J.S., Poulsen, M.N., Larsen, F., Molz, K.H. The AAPS journal [electronic resource]. (2006) [Pubmed]
  30. Mood and neuropsychological changes in women with midlife depression treated with escitalopram. Wroolie, T.E., Williams, K.E., Keller, J., Zappert, L.N., Shelton, S.D., Kenna, H.A., Reynolds, M.F., Rasgon, N.L. Journal of clinical psychopharmacology. (2006) [Pubmed]
  31. The R-enantiomer of citalopram counteracts escitalopram-induced increase in extracellular 5-HT in the frontal cortex of freely moving rats. Mørk, A., Kreilgaard, M., Sánchez, C. Neuropharmacology (2003) [Pubmed]
  32. Prediction of anti-panic properties of escitalopram in the dorsal periaqueductal grey model of panic anxiety. Hogg, S., Michan, L., Jessa, M. Neuropharmacology (2006) [Pubmed]
WikiGenes - Universities