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Chemical Compound Review

propanil     N-(3,4- dichlorophenyl)propanamide

Synonyms: Grascide, Propanex, Propanid, Riselect, Stampede, ...
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Disease relevance of propanil


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Biological context of propanil


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Gene context of propanil


Analytical, diagnostic and therapeutic context of propanil


  1. Propanil-induced methemoglobinemia and hemoglobin binding in the rat. McMillan, D.C., McRae, T.A., Hinson, J.A. Toxicol. Appl. Pharmacol. (1990) [Pubmed]
  2. Role of metabolites in propanil-induced hemolytic anemia. McMillan, D.C., Bradshaw, T.P., Hinson, J.A., Jollow, D.J. Toxicol. Appl. Pharmacol. (1991) [Pubmed]
  3. The immunomodulatory effects of the herbicide propanil on murine macrophage interleukin-6 and tumor necrosis factor-alpha production. Xie, Y.C., Schafer, R., Barnett, J.B. Toxicol. Appl. Pharmacol. (1997) [Pubmed]
  4. Propanil affects transcriptional and posttranscriptional regulation of IL-2 expression in activated EL-4 cells. Zhao, W., Schafer, R., Barnett, J.B. Toxicol. Appl. Pharmacol. (1999) [Pubmed]
  5. Inhibitory effect of 3,4-dichloro-propionaniline on cytokine production by macrophages is associated with LPS-mediated signal transduction. Xie, Y.C., Schafer, R., Barnett, J.B. J. Leukoc. Biol. (1997) [Pubmed]
  6. Propanil exposure induces delayed but sustained abrogation of cell-mediated immunity through direct interference with cytotoxic T-lymphocyte effectors. Sheil, J.M., Frankenberry, M.A., Schell, T.D., Brundage, K.M., Barnett, J.B. Environ. Health Perspect. (2006) [Pubmed]
  7. Evidence for a novel endocrine disruptor: the pesticide propanil requires the ovaries and steroid synthesis to enhance humoral immunity. Salazar, K.D., Miller, M.R., Barnett, J.B., Schafer, R. Toxicol. Sci. (2006) [Pubmed]
  8. Metabolism of the arylamide herbicide propanil. I. Microsomal metabolism and in vitro methemoglobinemia. McMillan, D.C., Freeman, J.P., Hinson, J.A. Toxicol. Appl. Pharmacol. (1990) [Pubmed]
  9. Characterization of thymic atrophy and the mechanism of thymocyte depletion after in vivo exposure to a mixture of herbicides. de la Rosa, P., Barnett, J.B., Schafer, R. J. Toxicol. Environ. Health Part A (2005) [Pubmed]
  10. Modeling and predicting selected immunological effects of a chemical stressor (3,4-dichloropropionanilide) using the area under the corticosterone concentration versus time curve. Pruett, S.B., Fan, R., Zheng, Q., Myers, L.P., Hébert, P. Toxicol. Sci. (2000) [Pubmed]
  11. Acute and chronic toxicity of the herbicide Stam M-4 in field and laboratory exposures. Moore, M.T., Farris, J.L. Arch. Environ. Contam. Toxicol. (1997) [Pubmed]
  12. Distribution and elimination of the herbicide propanil in the channel catfish (Ictalurus punctatus). Schlenk, D., Moore, C.T. Xenobiotica (1993) [Pubmed]
  13. Altered AP-1 (activating protein-1) activity and c-jun activation in T cells exposed to the amide class herbicide 3,4-dichloropropionanilide (DCPA). Brundage, K.M., Schafer, R., Barnett, J.B. Toxicol. Sci. (2004) [Pubmed]
  14. The polysaccharide antibody response after Streptococcus pneumoniae vaccination is differentially enhanced or suppressed by 3,4-dichloropropionanilide and 2,4-dichlorophenoxyacetic acid. Salazar, K.D., de la Rosa, P., Barnett, J.B., Schafer, R. Toxicol. Sci. (2005) [Pubmed]
  15. Propanil inhibits tumor necrosis factor-alpha production by reducing nuclear levels of the transcription factor nuclear factor-kappab in the macrophage cell line ic-21. Frost, L.L., Neeley, Y.X., Schafer, R., Gibson, L.F., Barnett, J.B. Toxicol. Appl. Pharmacol. (2001) [Pubmed]
  16. Metabolism of the arylamide herbicide propanil. II. Effects of propanil and its derivatives on hepatic microsomal drug-metabolizing enzymes in the rat. McMillan, D.C., Leakey, J.E., Arlotto, M.P., McMillan, J.M., Hinson, J.A. Toxicol. Appl. Pharmacol. (1990) [Pubmed]
  17. In vitro myelotoxicity of propanil and 3,4-dichloroaniline on murine and human CFU-E/BFU-E progenitors. Malerba, I., Castoldi, A.F., Parent-Massin, D., Gribaldo, L. Toxicol. Sci. (2002) [Pubmed]
  18. Compliance analysis of phenylurea and related compounds in drinking water by liquid chromatography/electrospray ionization/mass spectrometry coupled with solid-phase extraction. Li, Y., George, J.E., McCarty, C.L., Wendelken, S.C. Journal of chromatography. A (2006) [Pubmed]
  19. Use of the Drosophila wing spot test in the genotoxicity testing of different herbicides. Kaya, B., Creus, A., Yanikoğlu, A., Cabré, O., Marcos, R. Environ. Mol. Mutagen. (2000) [Pubmed]
  20. Cytokine production by C57BL/6 mouse spleen cells is selectively reduced by exposure to propanil. Zhao, W., Schafer, R., Barnett, J.B. J. Toxicol. Environ. Health Part A (1998) [Pubmed]
  21. Acute, chronic and sublethal effects of the herbicide propanil on Daphnia magna. Villarroel, M.J., Sancho, E., Ferrando, M.D., Andreu, E. Chemosphere (2003) [Pubmed]
  22. Determination of antagonism between cyhalofop-butyl and other rice (Oryza sativa) herbicides in barnyardgrass (Echinochloa crus-galli). Ottis, B.V., Mattice, J.D., Talbert, R.E. J. Agric. Food Chem. (2005) [Pubmed]
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