Chemical Compound Review:
Pyochelin (4S)-3-methyl-2-[(2E,4R)-2- (6-oxo-1...
Synonyms:
Pyochelins, AC1NUWEK, Chelins, pyo, CHEBI:29669, C12037, ...
- Possible role of bacterial siderophores in inflammation. Iron bound to the Pseudomonas siderophore pyochelin can function as a hydroxyl radical catalyst. Coffman, T.J., Cox, C.D., Edeker, B.L., Britigan, B.E. J. Clin. Invest. (1990)
- Binding properties of pyochelin and structurally related molecules to FptA of Pseudomonas aeruginosa. Mislin, G.L., Hoegy, F., Cobessi, D., Poole, K., Rognan, D., Schalk, I.J. J. Mol. Biol. (2006)
- Essential PchG-dependent reduction in pyochelin biosynthesis of Pseudomonas aeruginosa. Reimmann, C., Patel, H.M., Serino, L., Barone, M., Walsh, C.T., Haas, D. J. Bacteriol. (2001)
- Identification of rhtX and fptX, novel genes encoding proteins that show homology and function in the utilization of the siderophores rhizobactin 1021 by Sinorhizobium meliloti and pyochelin by Pseudomonas aeruginosa, respectively. Cuív, P.O., Clarke, P., Lynch, D., O'Connell, M. J. Bacteriol. (2004)
- Production and utilization of pyochelin by clinical isolates of Pseudomonas cepacia. Sokol, P.A. J. Clin. Microbiol. (1986)
- Interaction of the Pseudomonas aeruginosa secretory products pyocyanin and pyochelin generates hydroxyl radical and causes synergistic damage to endothelial cells. Implications for Pseudomonas-associated tissue injury. Britigan, B.E., Roeder, T.L., Rasmussen, G.T., Shasby, D.M., McCormick, M.L., Cox, C.D. J. Clin. Invest. (1992)
- Large-scale isolation of candidate virulence genes of Pseudomonas aeruginosa by in vivo selection. Wang, J., Mushegian, A., Lory, S., Jin, S. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Binding of iron-free siderophore, a common feature of siderophore outer membrane transporters of Escherichia coli and Pseudomonas aeruginosa. Hoegy, F., Celia, H., Mislin, G.L., Vincent, M., Gallay, J., Schalk, I.J. J. Biol. Chem. (2005)
- Isochorismate synthase (PchA), the first and rate-limiting enzyme in salicylate biosynthesis of Pseudomonas aeruginosa. Gaille, C., Reimmann, C., Haas, D. J. Biol. Chem. (2003)
- Importance of the ornibactin and pyochelin siderophore transport systems in Burkholderia cenocepacia lung infections. Visser, M.B., Majumdar, S., Hani, E., Sokol, P.A. Infect. Immun. (2004)
- Metal regulation of siderophore synthesis in Pseudomonas aeruginosa and functional effects of siderophore-metal complexes. Visca, P., Colotti, G., Serino, L., Verzili, D., Orsi, N., Chiancone, E. Appl. Environ. Microbiol. (1992)
- PchC thioesterase optimizes nonribosomal biosynthesis of the peptide siderophore pyochelin in Pseudomonas aeruginosa. Reimmann, C., Patel, H.M., Walsh, C.T., Haas, D. J. Bacteriol. (2004)
- Mechanism of augmentation of organotin decomposition by ferripyochelin: formation of hydroxyl radical and organotin-pyochelin-iron ternary complex. Sun, G.X., Zhong, J.J. Appl. Environ. Microbiol. (2006)
- PchR-box recognition by the AraC-type regulator PchR of Pseudomonas aeruginosa requires the siderophore pyochelin as an effector. Michel, L., González, N., Jagdeep, S., Nguyen-Ngoc, T., Reimmann, C. Mol. Microbiol. (2005)
- PchR, a regulator of ferripyochelin receptor gene (fptA) expression in Pseudomonas aeruginosa, functions both as an activator and as a repressor. Heinrichs, D.E., Poole, K. J. Bacteriol. (1996)
- Cloning and sequence analysis of a gene (pchR) encoding an AraC family activator of pyochelin and ferripyochelin receptor synthesis in Pseudomonas aeruginosa. Heinrichs, D.E., Poole, K. J. Bacteriol. (1993)
- Ability of Pseudomonas pseudomallei malleobactin to acquire transferrin-bound, lactoferrin-bound, and cell-derived iron. Yang, H., Kooi, C.D., Sokol, P.A. Infect. Immun. (1993)
- Augmentation of oxidant injury to human pulmonary epithelial cells by the Pseudomonas aeruginosa siderophore pyochelin. Britigan, B.E., Rasmussen, G.T., Cox, C.D. Infect. Immun. (1997)
- Siderophore-mediated iron acquisition from transferrin by Pseudomonas aeruginosa. Sriyosachati, S., Cox, C.D. Infect. Immun. (1986)
- Pyelonephritic potential of Pseudomonas aeruginosa in ascending mouse model. Yadav, V., Harjai, K., Joshi, K., Sharma, S. Indian J. Med. Res. (2000)
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- Carrier protein recognition in siderophore-producing nonribosomal peptide synthetases. Marshall, C.G., Burkart, M.D., Meray, R.K., Walsh, C.T. Biochemistry (2002)
- Synthesis and biological activity of pyochelin, a siderophore of Pseudomonas aeruginosa. Ankenbauer, R.G., Toyokuni, T., Staley, A., Rinehart, K.L., Cox, C.D. J. Bacteriol. (1988)
- Ferric uptake regulator (Fur) mutants of Pseudomonas aeruginosa demonstrate defective siderophore-mediated iron uptake, altered aerobic growth, and decreased superoxide dismutase and catalase activities. Hassett, D.J., Sokol, P.A., Howell, M.L., Ma, J.F., Schweizer, H.T., Ochsner, U., Vasil, M.L. J. Bacteriol. (1996)
- Pseudomonas fluorescens CHA0 produces enantio-pyochelin, the optical antipode of the Pseudomonas aeruginosa siderophore pyochelin. Youard, Z.A., Mislin, G.L., Majcherczyk, P.A., Schalk, I.J., Reimmann, C. J. Biol. Chem. (2007)
- Salicylate biosynthesis in Pseudomonas aeruginosa. Purification and characterization of PchB, a novel bifunctional enzyme displaying isochorismate pyruvate-lyase and chorismate mutase activities. Gaille, C., Kast, P., Haas, D. J. Biol. Chem. (2002)
- Isolation and characterization of Pseudomonas aeruginosa genes inducible by respiratory mucus derived from cystic fibrosis patients. Wang, J., Lory, S., Ramphal, R., Jin, S. Mol. Microbiol. (1996)
- Biosynthesis of pyochelin and dihydroaeruginoic acid requires the iron-regulated pchDCBA operon in Pseudomonas aeruginosa. Serino, L., Reimmann, C., Visca, P., Beyeler, M., Chiesa, V.D., Haas, D. J. Bacteriol. (1997)
- Mutasynthesis of siderophore analogues by Pseudomonas aeruginosa. Ankenbauer, R.G., Staley, A.L., Rinehart, K.L., Cox, C.D. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Crystallization and X-ray diffraction analyses of the outer membrane pyochelin receptor FptA from Pseudomonas aeruginosa. Cobessi, D., Célia, H., Pattus, F. Acta Crystallogr. D Biol. Crystallogr. (2004)
- Different iron-chelating properties of pyochelin diastereoisomers revealed by LC/MS. Hayen, H., Volmer, D.A. Analytical and bioanalytical chemistry. (2006)