Chemical Compound Review:
Spasmomen diethyl-methyl-[2-[4-[(2...
Synonyms:
Octylonium, SP63, SureCN109554, AG-E-81199, CHEMBL2103773, ...
This record was replaced with 72093.
- Otilonium bromide in irritable bowel syndrome: a double-blind, placebo-controlled, 15-week study. Battaglia, G., Morselli-Labate, A.M., Camarri, E., Francavilla, A., De Marco, F., Mastropaolo, G., Naccarato, R. Aliment. Pharmacol. Ther. (1998)
- Irritable bowel syndrome. Spinelli, A. Clinical drug investigation (2007)
- Assessment of potential selectivity of antispasmodics for the various sections of the gastrointestinal tract of the rat as a guideline for their clinical use. Maggi, C.A., Meli, A. Archives internationales de pharmacodynamie et de thérapie. (1983)
- Effects exerted by otilonium bromide administration on precipitated opioid withdrawal syndrome in rats. Pinelli, A., Trivulzio, S., Vignati, S. Toxicology (1997)
- Colonic motility and gastric emptying in patients with irritable bowel syndrome. Effect of pretreatment with octylonium bromide. Narducci, F., Bassotti, G., Granata, M.T., Pelli, M.A., Gaburri, M., Palumbo, R., Morelli, A. Dig. Dis. Sci. (1986)
- Otilonium bromide enhances sensory thresholds of volume and pressure in patients with irritable bowel syndrome. Czimmer, J., Süto, G., Király, A., Mózsik, G. J. Physiol. Paris (2001)
- Octylonium bromide in the treatment of the irritable bowel syndrome: a clinical-functional study. Baldi, F., Longanesi, A., Blasi, A., Monello, S., Cestari, R., Missale, G., Corazziari, E., Badiali, G., Marzio, L., Di Felice, F. Hepatogastroenterology (1992)
- Meta-analysis: The treatment of irritable bowel syndrome. Lesbros-Pantoflickova, D., Michetti, P., Fried, M., Beglinger, C., Blum, A.L. Aliment. Pharmacol. Ther. (2004)
- The colon-selective spasmolytic otilonium bromide inhibits muscarinic M(3) receptor-coupled calcium signals in isolated human colonic crypts. Lindqvist, S., Hernon, J., Sharp, P., Johns, N., Addison, S., Watson, M., Tighe, R., Greer, S., Mackay, J., Rhodes, M., Lewis, M., Stebbings, W., Speakman, C., Evangelista, S., Johnson, I., Williams, M. Br. J. Pharmacol. (2002)
- Platelet-activating factor regulates chloride transport in colonic epithelial cell monolayers. Claud, E.C., Li, D., Xiao, Y., Caplan, M.S., Jilling, T. Pediatr. Res. (2002)
- Otilonium bromide inhibits muscle contractions via L-type calcium channels in the rat colon. Martin, M.T., Hove-Madsen, L., Jimenez, M. Neurogastroenterol. Motil. (2004)
- A distribution study with (14)C-otilonium bromide in the rat: evidence for selective tropism for large intestine after oral administration. Evangelista, S., Cochet, P., Bromet, N., Criscuoli, M., Maggi, C.A. Drug Metab. Dispos. (2000)
- Antimuscarinic, calcium channel blocker and tachykinin NK2 receptor antagonist actions of otilonium bromide in the circular muscle of guinea-pig colon. Santicioli, P., Zagorodnyuk, V., Renzetti, A.R., Maggi, C.A. Naunyn Schmiedebergs Arch. Pharmacol. (1999)
- The clinical pharmacology of single doses of otilonium bromide in healthy volunteers. Sutton, J.A., Kilminster, S.G., Mould, G.P. Eur. J. Clin. Pharmacol. (1997)
- Receptor binding profile of Otilonium bromide. Evangelista, S., Giachetti, A., Chapelain, B., Neliat, G., Maggi, C.A. Pharmacol. Res. (1998)
- Blocking effects of otilonium on Ca2+ channels and secretion in rat chromaffin cells. Gandía, L., López, M.G., Villarroya, M., Gilabert, J.A., Cárdenas, A., García, A.G., Borges, R. Eur. J. Pharmacol. (1996)
- Octylonium bromide: a smooth muscle relaxant which interferes with calcium ions mobilization. Maggi, C.A., Manzini, S., Meli, A. Archives internationales de pharmacodynamie et de thérapie. (1983)
- High-performance liquid chromatographic method for assay of otilonium bromide, diazepam, and related compounds in finished pharmaceutical forms. Mannucci, C., Bertini, J., Cocchini, A., Perico, A., Salvagnini, F., Triolo, A. Journal of pharmaceutical sciences. (1993)
- Stability-indicating methods for determining omeprazole and octylonium bromide in the presence of their degradation products. el-Kousy, N.M., Bebawy, L.I. Journal of AOAC International. (1999)
- Clinical and functional evaluation of the efficacy of otilonium bromide: a multicenter study in Italy. Baldi, F., Longanesi, A., Blasi, A., Monello, S., Cestari, R., Missale, G., Corazziari, E., Badiali, G., Pescatori, M., Anastasio, G. The Italian journal of gastroenterology. (1991)