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Chemical Compound Review

KST-1A1565     (3S)-2,3-dihydroxybutanedioic acid

Synonyms: AC1L2WBV, AC1Q5QUM, AR-1A3172, 147-73-9, EINECS 205-696-1, ...
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Disease relevance of tartaric acid


High impact information on tartaric acid

  • We present X-ray photoelectron spectroscopy (XPS) and X-ray photoelectron diffraction (XPD) investigations of CuO thin films electrochemically deposited on an Au(001) single-crystal surface from a solution containing chiral tartaric acid (TA) [6].
  • Topotecan is stable in infusion fluids in the presence of tartaric acid (pH < 4.0), but is unstable in plasma, requiring immediate deproteinisation with cold methanol after blood sampling and storage of the extract at -30 degrees C to preserve the lactone form [7].
  • 4. PAP activity was assessed by subtracting tartaric acid-inhibited acid phosphatase activity from total acid phosphatase activity [8].
  • The basement membrane from bovine lens as well as type IV collagen prepared from it by tartaric acid extraction did not activate the human neutrophils [9].
  • Effects of methacholine induced bronchoconstriction and procaterol induced bronchodilation on cough receptor sensitivity to inhaled capsaicin and tartaric acid [10].

Chemical compound and disease context of tartaric acid


Biological context of tartaric acid


Anatomical context of tartaric acid


Associations of tartaric acid with other chemical compounds


Gene context of tartaric acid


Analytical, diagnostic and therapeutic context of tartaric acid


  1. Use of tartaric acid resistance of beta-glucuronidase for the characterization of cancer cells in pleural effusions. Apibal, S., Sestapruks, P., Bunyaratvej, A., Srivannaboon, S., Charoenpan, P. Acta Cytol. (1987) [Pubmed]
  2. Assessing the laryngeal cough reflex and the risk of developing pneumonia after stroke. Addington, W.R., Stephens, R.E., Gilliland, K., Rodriguez, M. Archives of physical medicine and rehabilitation. (1999) [Pubmed]
  3. Tartaric Acid recovery from distilled lees and use of the residual solid as an economic nutrient for lactobacillus. Rivas, B., Torrado, A., Moldes, A.B., Dom??nguez, J.M. J. Agric. Food Chem. (2006) [Pubmed]
  4. Cough receptor sensitivity to capsaicin and tartaric acid in patients with Mycoplasma pneumonia. Fujimura, M., Myou, S., Matsuda, M., Amemiya, T., Kamio, Y., Iwasa, K., Ishiura, Y., Yasui, M., Tagami, A., Matsuda, T. Lung (1998) [Pubmed]
  5. Morbid obesity treated with gastric partitioning and gastrogastrostomy. Amland, P.F., Tofte, A.J., Jorde, R., Johnson, J.A., Gjøen, A.U., Giercksky, K.E. Scand. J. Gastroenterol. (1986) [Pubmed]
  6. Surface Chirality of CuO Thin Films. Widmer, R., Haug, F.J., Ruffieux, P., Gr??ning, O., Bielmann, M., Gr??ning, P., Fasel, R. J. Am. Chem. Soc. (2006) [Pubmed]
  7. Clinical pharmacokinetics of topotecan. Herben, V.M., ten Bokkel Huinink, W.W., Beijnen, J.H. Clinical pharmacokinetics. (1996) [Pubmed]
  8. Prostatic acid phosphatase assay with self-indicating substrate 2,6-dichloro-4-acetylphenyl phosphate. Osawa, S., Iida, S., Yonemitsu, H., Kuroiwa, K., Katayama, K., Nagasawa, T. Clin. Chem. (1995) [Pubmed]
  9. Adhesion and activation of human neutrophils on basement membrane molecules. Borel, J.P., Bellon, G., Garnotel, R., Monboisse, J.C. Kidney Int. (1993) [Pubmed]
  10. Effects of methacholine induced bronchoconstriction and procaterol induced bronchodilation on cough receptor sensitivity to inhaled capsaicin and tartaric acid. Fujimura, M., Sakamoto, S., Kamio, Y., Matsuda, T. Thorax (1992) [Pubmed]
  11. The effect of alpha-difluromethylornithine and tartaric acid on sperm count, seminal gamma GT, FSH, LH, testosterone and steroid excretion in patients with chronic prostatitis. Dunzendorfer, U., Feller, H. Andrologia (1981) [Pubmed]
  12. Sex difference in the inhaled tartaric acid cough threshold in non-atopic healthy subjects. Fujimura, M., Sakamoto, S., Kamio, Y., Matsuda, T. Thorax (1990) [Pubmed]
  13. Dipyridamole bioavailability in subjects with reduced gastric acidity. Derendorf, H., VanderMaelen, C.P., Brickl, R.S., MacGregor, T.R., Eisert, W. Journal of clinical pharmacology. (2005) [Pubmed]
  14. Cough receptor sensitivity and bronchial responsiveness in normal and asthmatic subjects. Fujimura, M., Sakamoto, S., Kamio, Y., Matsuda, T. Eur. Respir. J. (1992) [Pubmed]
  15. Anesthesia for the superior laryngeal nerves and tartaric acid-induced cough. Addington, W.R., Stephens, R.E., Goulding, R.E. Archives of physical medicine and rehabilitation. (1999) [Pubmed]
  16. Tartaric acid-induced cough and the superior laryngeal nerve evoked potential. Addington, W.R., Stephens, R.E., Gilliland, K., Miller, S.P. American journal of physical medicine & rehabilitation / Association of Academic Physiatrists. (1998) [Pubmed]
  17. Acute esophageal food impaction treated by gas-forming agents. Rice, B.T., Spiegel, P.K., Dombrowski, P.J. Radiology. (1983) [Pubmed]
  18. A parallel between two techniques of extraction of connective tissue macromolecules. Bellon, G., Wegrowski, J., Perreau, C., Randoux, A., Borel, J.P., Malgras, A., Chastang, F. Anal. Biochem. (1988) [Pubmed]
  19. Relationships between spontaneous discharge rates and taste responses of the dog thalamic neurons. Ninomiya, Y., Funakoshi, M. Brain Res. (1982) [Pubmed]
  20. Determination of peptides by capillary electrophoresis-electrochemical detection using on-column Cu(II) complexation. Deacon, M., O'Shea, T.J., Lunte, S.M., Smyth, M.R. Journal of chromatography. A. (1993) [Pubmed]
  21. Enhanced fluorescence and chiral discrimination for tartaric acid in a dual fluorophore boronic acid receptor. Zhao, J., James, T.D. Chem. Commun. (Camb.) (2005) [Pubmed]
  22. Phosphorylation status of nuclear and cytosolic androgen receptors in the rat ventral prostate. Golsteyn, E.J., Graham, J.S., Goren, H.J., Lefebvre, Y.A. Prostate (1989) [Pubmed]
  23. The hygroscopic properties of dicarboxylic and multifunctional acids: measurements and UNIFAC predictions. Peng, C., Chan, M.N., Chan, C.K. Environ. Sci. Technol. (2001) [Pubmed]
  24. Nearest-neighbor nonparametric method for estimating the configurational entropy of complex molecules. Hnizdo, V., Darian, E., Fedorowicz, A., Demchuk, E., Li, S., Singh, H. Journal of computational chemistry (2007) [Pubmed]
  25. Effects of clozapine and haloperidol on baseline levels of vacuous jaw movements in aged rats. Steinpreis, R.E., Parret, F., Summ, R.M., Panos, J.J. Behav. Brain Res. (1997) [Pubmed]
  26. Effect of tartaric acid on conformation and stability of human prostatic phosphatase: an infrared spectroscopic and calorimetric study. Bem, S., Ostrowski, W.S. Acta Biochim. Pol. (2001) [Pubmed]
  27. Reactions in glass ionomer cements: V. Effect of incorporating tartaric acid in the cement liquid. Crisp, S., Wilson, A.D. J. Dent. Res. (1976) [Pubmed]
  28. Influence of D(-) and L(+) tartaric acid on lysozyme adsorption onto a Si(Ti)-O2 surface. Ball, V., Ramsden, J.J. Naturwissenschaften (1998) [Pubmed]
  29. Cloning of a gluconate/polyol dehydrogenase gene from Gluconobacter suboxydans IFO 12528, characterisation of the enzyme and its use for the production of 5-ketogluconate in a recombinant Escherichia coli strain. Salusjärvi, T., Povelainen, M., Hvorslev, N., Eneyskaya, E.V., Kulminskaya, A.A., Shabalin, K.A., Neustroev, K.N., Kalkkinen, N., Miasnikov, A.N. Appl. Microbiol. Biotechnol. (2004) [Pubmed]
  30. Fungal bioconversion of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4-dichlorophenol (2,4-DCP). Vroumsia, T., Steiman, R., Seigle-Murandi, F., Benoit-Guyod, J.L. Chemosphere (2005) [Pubmed]
  31. Liquid chromatography with mass spectrometry in tandem mode applied for the identification of wine markers in residues from ancient Egyptian vessels. Guasch-Jané, M.R., Ibern-Gómez, M., Andrés-Lacueva, C., Jáuregui, O., Lamuela-Raventós, R.M. Anal. Chem. (2004) [Pubmed]
  32. Determination of tartaric acid in solid wine residues by capillary electrophoresis and indirect UV detection. Mallet, S., Arellano, M., Boulet, J.C., Couderc, F. Journal of chromatography. A. (1999) [Pubmed]
  33. Adsorption and coordination of tartaric acid enantiomers on Cu(111) in aqueous solution. Yan, H.J., Wang, D., Han, M.J., Wan, L.J., Bai, C.L. Langmuir : the ACS journal of surfaces and colloids. (2004) [Pubmed]
  34. Identification of oxalic acid and tartaric acid as major persistent pain-inducing toxins in the stinging hairs of the nettle, Urtica thunbergiana. Fu, H.Y., Chen, S.J., Chen, R.F., Ding, W.H., Kuo-Huang, L.L., Huang, R.N. Ann. Bot. (2006) [Pubmed]
  35. Packed column supercritical fluid chromatography of sodium stearyl fumarate aqueous suspension. Gyllenhaal, O. Journal of pharmaceutical and biomedical analysis. (2006) [Pubmed]
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