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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Wettability


High impact information on Wettability

  • In this study we investigated the effects of acidified aspirin on the wettability of the luminal surface of gastric mucosae mounted in Ussing chambers in the presence of varying concentrations of 16,16-dimethyl prostaglandin E2 [6].
  • Imidazolium ion-terminated self-assembled monolayers on Au: effects of counteranions on surface wettability [7].
  • The examination of wettability of the copolymer surfaces showed that the contact angle of water on the hydrophobic surfaces is an increasing linear function of styrene content in the copolymer [8].
  • The negativity and wettability of surfaces of polystyrene beads and plates can be increased by pretreatment with acid, and adhesion of haemocytes to these modified surfaces has been examined in vivo and in vitro [9].
  • Photoswitched wettability on inverse opal modified by a self-assembled azobenzene monolayer [10].

Biological context of Wettability


Anatomical context of Wettability


Associations of Wettability with chemical compounds

  • An increase in wettability of the tugsten surface after growing randomly oriented TON on its surface allows strong adhesion of approximately 50 nL of the methanol solution at its tip [21].
  • In addition, the wettability of the titanium surface was measured with and without GDP [22].
  • Ambient sulfate aerosol deposition in man: modeling the influence of hygroscopicity [23].
  • SAMs exhibited various substratum compositions and wettabilities, ranging from hydrophilic, hydroxyl-terminated monolayers to hydrophobic, methyl-terminated monolayers [24].
  • This spice-induced increase in surface wettability was long-lasting, could be enhanced in the presence of ethanol and reversed by post-treating the rats with BSS [25].

Gene context of Wettability

  • This study shows that regardless of wettability and the biomaterial used, initial adhesion of platelets appears to be mediated by GPIIb/IIIa binding to surface adsorbed fibrinogen [26].
  • We demonstrated that the decreasing wettability of the materials significantly reduced endogenous fibronectin deposition on the substratum [27].
  • The relationship between lens wettability, back surface deposits, and steeper corneal curvature with mucin balls supports the hypothesis that the mechanical interaction of a lens with the surface layer of the epithelium and the tear film in association with the blinking forces of the lid is involved in mucin ball formation [28].
  • The AEP and the actual electroosmotic mobility should allow a better understanding of the perfusive EOF and stationary-phase wettability [29].
  • TL may have an important role in removing lipids from the corneal surface to maintain the wettability and integrity of the ocular surface [30].

Analytical, diagnostic and therapeutic context of Wettability


  1. Effect of a combined gamma irradiation and Parylene plasma treatment on the hydrolytic degradation of synthetic biodegradable sutures. Zhang, L., Chu, C.C., Loh, I.H. J. Biomed. Mater. Res. (1993) [Pubmed]
  2. Optimization of an alum-adsorbed vaccine powder formulation for epidermal powder immunization. Maa, Y.F., Shu, C., Ameri, M., Zuleger, C., Che, J., Osorio, J.E., Payne, L.G., Chen, D. Pharm. Res. (2003) [Pubmed]
  3. Primary bacterial colonization of implant surfaces. Drake, D.R., Paul, J., Keller, J.C. The International journal of oral & maxillofacial implants. (1999) [Pubmed]
  4. "Inert" formulation ingredients with activity: toxicity of trisiloxane surfactant solutions to twospotted spider mites (Acari: Tetranychidae). Cowles, R.S., Cowles, E.A., McDermott, A.M., Ramoutar, D. J. Econ. Entomol. (2000) [Pubmed]
  5. Clinical performances of two disposable soft contact lenses of different materials on Hong Kong-Chinese. Cho, P., Ng, V. Contact lens & anterior eye : the journal of the British Contact Lens Association. (2000) [Pubmed]
  6. Effect of 16,16-dimethyl prostaglandin E2 on the surface hydrophobicity of aspirin-treated canine gastric mucosa. Lichtenberger, L.M., Richards, J.E., Hills, B.A. Gastroenterology (1985) [Pubmed]
  7. Imidazolium ion-terminated self-assembled monolayers on Au: effects of counteranions on surface wettability. Lee, B.S., Chi, Y.S., Lee, J.K., Choi, I.S., Song, C.E., Namgoong, S.K., Lee, S.G. J. Am. Chem. Soc. (2004) [Pubmed]
  8. Adhesion of L1210 cells to modified styrene copolymer surfaces in the presence of serum. Kowalczynska, H.M., Kaminski, J. J. Cell. Sci. (1991) [Pubmed]
  9. Effect of substratum wettability and charge on adhesion in vitro and encapsulation in vivo by insect haemocytes. Lackie, A.M. J. Cell. Sci. (1983) [Pubmed]
  10. Photoswitched wettability on inverse opal modified by a self-assembled azobenzene monolayer. Ge, H., Wang, G., He, Y., Wang, X., Song, Y., Jiang, L., Zhu, D. Chemphyschem : a European journal of chemical physics and physical chemistry. (2006) [Pubmed]
  11. Effect of culture substrates and fibroblast growth factor addition on the proliferation and differentiation of rat bone marrow stromal cells. Hori, Y., Inoue, S., Hirano, Y., Tabata, Y. Tissue engineering. (2004) [Pubmed]
  12. Hygroscopicity of water-soluble organic compounds in atmospheric aerosols: amino acids and biomass burning derived organic species. Chan, M.N., Choi, M.Y., Ng, N.L., Chan, C.K. Environ. Sci. Technol. (2005) [Pubmed]
  13. Preparation and in vitro evaluation of solid dispersions of halofantrine. Abdul-Fattah, A.M., Bhargava, H.N. International journal of pharmaceutics. (2002) [Pubmed]
  14. Effect of immersion disinfection on properties of impression materials. Davis, B.A., Powers, J.M. Journal of prosthodontics : official journal of the American College of Prosthodontists. (1994) [Pubmed]
  15. Stability of the powdered dosage form prepared by unsealing the capsules: water vapor sorption and discoloration of the powdery contents of clorazepate dipotassium capsules. Hanawa, T., Ohta, T., Kimura, F., Tsuchiya, T., Ikoma, R., Uchida, T., Suzuki, M., Nakajima, S. Drug development and industrial pharmacy. (2000) [Pubmed]
  16. Microfluidic immunoassay for bacterial toxins with supported phospholipid bilayer membranes on poly(dimethylsiloxane). Phillips, K.S., Cheng, Q. Anal. Chem. (2005) [Pubmed]
  17. Surface hydrophobicity and water transport of the toad urinary bladder: effects of vasopressin. Dial, E.J., Huang, J., O'Neil, R.G., Hills, B.A., Lichtenberger, L.M. J. Membr. Biol. (1988) [Pubmed]
  18. Studies on the biocompatibility of materials: fibroblast reorganization of substratum-bound fibronectin on surfaces varying in wettability. Altankov, G., Grinnell, F., Groth, T. J. Biomed. Mater. Res. (1996) [Pubmed]
  19. Plasma-treated polystyrene surfaces: model surfaces for studying cell-biomaterial interactions. van Kooten, T.G., Spijker, H.T., Busscher, H.J. Biomaterials (2004) [Pubmed]
  20. Adhesion of cultured human endothelial cells onto methacrylate polymers with varying surface wettability and charge. van Wachem, P.B., Hogt, A.H., Beugeling, T., Feijen, J., Bantjes, A., Detmers, J.P., van Aken, W.G. Biomaterials (1987) [Pubmed]
  21. Electrospray from nanostructured tungsten oxide surfaces with ultralow sample volume. Jeng, J., Lin, C.H., Shiea, J. Anal. Chem. (2005) [Pubmed]
  22. Anode glow discharge plasma treatment enhances calcium phosphate adsorption onto titanium plates. Shibata, Y., Miyazaki, T. J. Dent. Res. (2002) [Pubmed]
  23. Ambient sulfate aerosol deposition in man: modeling the influence of hygroscopicity. Martonen, T.B., Barnett, A.E., Miller, F.J. Environ. Health Perspect. (1985) [Pubmed]
  24. Bacterial adhesion to hydroxyl- and methyl-terminated alkanethiol self-assembled monolayers. Wiencek, K.M., Fletcher, M. J. Bacteriol. (1995) [Pubmed]
  25. Effect of pepper and bismuth subsalicylate on gastric pain and surface hydrophobicity in the rat. Lichtenberger, L.M., Romero, J.J., Carryl, O.R., Illich, P.A., Walters, E.T. Aliment. Pharmacol. Ther. (1998) [Pubmed]
  26. GpIIb/IIIa is the main receptor for initial platelet adhesion to glass and titanium surfaces in contact with whole blood. Broberg, M., Eriksson, C., Nygren, H. J. Lab. Clin. Med. (2002) [Pubmed]
  27. Fibronectin matrix formation by human fibroblasts on surfaces varying in wettability. Altankov, G., Groth, T. Journal of biomaterials science. Polymer edition. (1996) [Pubmed]
  28. Mucin balls with wear of conventional and silicone hydrogel contact lenses. Tan, J., Keay, L., Jalbert, I., Naduvilath, T.J., Sweeney, D.F., Holden, B.A. Optometry and vision science : official publication of the American Academy of Optometry. (2003) [Pubmed]
  29. Selection of two reliable parameters to evaluate the impact of the mobile-phase composition on capillary electrochromatography performance with monolithic and particle-packed capillary columns. Progent, F., Augustin, V., Tran, N.T., Descroix, S., Taverna, M. Electrophoresis (2006) [Pubmed]
  30. Tear lipocalin: evidence for a scavenging function to remove lipids from the human corneal surface. Gasymov, O.K., Abduragimov, A.R., Prasher, P., Yusifov, T.N., Glasgow, B.J. Invest. Ophthalmol. Vis. Sci. (2005) [Pubmed]
  31. Integrin expression and osteopontin regulation in human fetal osteoblastic cells mediated by substratum surface characteristics. Lim, J.Y., Taylor, A.F., Li, Z., Vogler, E.A., Donahue, H.J. Tissue engineering. (2005) [Pubmed]
  32. Phosphorylcholine-containing polyurethanes for the control of protein adsorption and cell attachment via photoimmobilized laminin oligopeptides. Ruiz, L., Fine, E., Vörös, J., Makohliso, S.A., Léonard, D., Johnston, D.S., Textor, M., Mathieu, H.J. Journal of biomaterials science. Polymer edition. (1999) [Pubmed]
  33. Swelling behavior of organoclays in styrene and exfoliation in nanocomposites. Fu, X.A., Qutubuddin, S. Journal of colloid and interface science. (2005) [Pubmed]
  34. Wettability studies of morphine sulfate powders. Prestidge, C.A., Tsatouhas, G. International journal of pharmaceutics. (2000) [Pubmed]
  35. Analogies in the two-dimensional spatial arrangement of adsorbed proteins and adhering bacteria: bovine serum albumin and Streptococcus sanguis 12. Busscher, H.J., van der Mei, H.C., Schakenraad, J.M. Journal of biomaterials science. Polymer edition. (1991) [Pubmed]
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