Gene Review:
TUBB4A - tubulin, beta 4A class IVa
Homo sapiens
Synonyms:
DYT4, TUBB4, TUBB5, Tubulin 5 beta, Tubulin beta-4 chain, ...
- Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Wickham, T.J., Mathias, P., Cheresh, D.A., Nemerow, G.R. Cell (1993)
- Alpha v beta 5 integrin-dependent programmed cell death triggered by a peptide mimic of annexin V. Cardó-Vila, M., Arap, W., Pasqualini, R. Mol. Cell (2003)
- Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface. Wayner, E.A., Orlando, R.A., Cheresh, D.A. J. Cell Biol. (1991)
- Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation. Lewis, J.M., Cheresh, D.A., Schwartz, M.A. J. Cell Biol. (1996)
- Integrin alpha v beta 5 selectively promotes adenovirus mediated cell membrane permeabilization. Wickham, T.J., Filardo, E.J., Cheresh, D.A., Nemerow, G.R. J. Cell Biol. (1994)
- AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection. Summerford, C., Bartlett, J.S., Samulski, R.J. Nat. Med. (1999)
- The production of a new MAGE-3 peptide presented to cytolytic T lymphocytes by HLA-B40 requires the immunoproteasome. Schultz, E.S., Chapiro, J., Lurquin, C., Claverol, S., Burlet-Schiltz, O., Warnier, G., Russo, V., Morel, S., Lévy, F., Boon, T., Van den Eynde, B.J., van der Bruggen, P. J. Exp. Med. (2002)
- Vitronectin expression in differentiating neuroblastic tumors: integrin alpha v beta 5 mediates vitronectin-dependent adhesion of retinoic-acid-differentiated neuroblastoma cells. Gladson, C.L., Dennis, C., Rotolo, T.C., Kelly, D.R., Grammer, J.R. Am. J. Pathol. (1997)
- Activity patterns of proteasome subunits reflect bortezomib sensitivity of hematologic malignancies and are variable in primary human leukemia cells. Kraus, M., R??ckrich, T., Reich, M., Gogel, J., Beck, A., Kammer, W., Berkers, C.R., Burg, D., Overkleeft, H., Ovaa, H., Driessen, C. Leukemia (2007)
- Effects of phospholipid unsaturation on the bilayer nonpolar region: a molecular simulation study. Róg, T., Murzyn, K., Gurbiel, R., Takaoka, Y., Kusumi, A., Pasenkiewicz-Gierula, M. J. Lipid Res. (2004)
- Contrasting roles for integrin beta 1 and beta 5 cytoplasmic domains in subcellular localization, cell proliferation, and cell migration. Pasqualini, R., Hemler, M.E. J. Cell Biol. (1994)
- Switch from alphavbeta5 to alphavbeta6 integrin expression protects squamous cell carcinomas from anoikis. Janes, S.M., Watt, F.M. J. Cell Biol. (2004)
- Characterization of the integrin receptor subunit profile in the mammalian sclera. Metlapally, R., Jobling, A.I., Gentle, A., McBrien, N.A. Mol. Vis. (2006)
- Localization of a site on bacterial superantigens that determines T cell receptor beta chain specificity. Mollick, J.A., McMasters, R.L., Grossman, D., Rich, R.R. J. Exp. Med. (1993)
- Cloning, primary structure and properties of a novel human integrin beta subunit. Ramaswamy, H., Hemler, M.E. EMBO J. (1990)
- Polarized expression of integrin receptors (alpha 6 beta 4, alpha 2 beta 1, alpha 3 beta 1, and alpha v beta 5) and their relationship with the cytoskeleton and basement membrane matrix in cultured human keratinocytes. Marchisio, P.C., Bondanza, S., Cremona, O., Cancedda, R., De Luca, M. J. Cell Biol. (1991)
- Thyrostimulin, a heterodimer of two new human glycoprotein hormone subunits, activates the thyroid-stimulating hormone receptor. Nakabayashi, K., Matsumi, H., Bhalla, A., Bae, J., Mosselman, S., Hsu, S.Y., Hsueh, A.J. J. Clin. Invest. (2002)
- Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin. Klemke, R.L., Yebra, M., Bayna, E.M., Cheresh, D.A. J. Cell Biol. (1994)
- A novel integrin specificity exemplified by binding of the alpha v beta 5 integrin to the basic domain of the HIV Tat protein and vitronectin. Vogel, B.E., Lee, S.J., Hildebrand, A., Craig, W., Pierschbacher, M.D., Wong-Staal, F., Ruoslahti, E. J. Cell Biol. (1993)
- Inhibition of cell adhesion by antibodies to Arg-Gly-Asp (RGD) in normal immunoglobulin for therapeutic use (intravenous immunoglobulin, IVIg). Vassilev, T.L., Kazatchkine, M.D., Van Huyen, J.P., Mekrache, M., Bonnin, E., Mani, J.C., Lecroubier, C., Korinth, D., Baruch, D., Schriever, F., Kaveri, S.V. Blood (1999)
- Direct integrin alphavbeta6-ERK binding: implications for tumour growth. Ahmed, N., Niu, J., Dorahy, D.J., Gu, X., Andrews, S., Meldrum, C.J., Scott, R.J., Baker, M.S., Macreadie, I.G., Agrez, M.V. Oncogene (2002)
- Heterologous expression and folding analysis of a beta-tubulin isotype from the Antarctic ciliate Euplotes focardii. Pucciarelli, S., Miceli, C., Melki, R. Eur. J. Biochem. (2002)
- Overexpressed Csk tyrosine kinase is localized in focal adhesions, causes reorganization of alpha v beta 5 integrin, and interferes with HeLa cell spreading. Bergman, M., Joukov, V., Virtanen, I., Alitalo, K. Mol. Cell. Biol. (1995)
- Purification and functional characterization of integrin alpha v beta 5. An adhesion receptor for vitronectin. Smith, J.W., Vestal, D.J., Irwin, S.V., Burke, T.A., Cheresh, D.A. J. Biol. Chem. (1990)
- Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit. Ermakova, I., Boldyreff, B., Issinger, O.G., Niefind, K. J. Mol. Biol. (2003)
- Activation and inhibition of G protein-coupled inwardly rectifying potassium (Kir3) channels by G protein beta gamma subunits. Lei, Q., Jones, M.B., Talley, E.M., Schrier, A.D., McIntire, W.E., Garrison, J.C., Bayliss, D.A. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Differential activity of the G protein beta5 gamma2 subunit at receptors and effectors. Lindorfer, M.A., Myung, C.S., Savino, Y., Yasuda, H., Khazan, R., Garrison, J.C. J. Biol. Chem. (1998)
- Modulation of estrogen receptor-beta isoforms by phytoestrogens in breast cancer cells. Cappelletti, V., Miodini, P., Di Fronzo, G., Daidone, M.G. Int. J. Oncol. (2006)
- A C-helix Residue, Arg-123, Has Important Roles in Both the Active and Inactive Forms of the cAMP Receptor Protein. Youn, H., Kerby, R.L., Koh, J., Roberts, G.P. J. Biol. Chem. (2007)
- P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration. Zhang, H., Li, Z., Viklund, E.K., Strömblad, S. J. Cell Biol. (2002)
- Characterisation of the newly identified human Ump1 homologue POMP and analysis of LMP7(beta 5i) incorporation into 20 S proteasomes. Witt, E., Zantopf, D., Schmidt, M., Kraft, R., Kloetzel, P.M., Krüger, E. J. Mol. Biol. (2000)
- Allorecognition and T cell repertoire selection in severe combined immunodeficiency lacking HLA class II antigens. Knobloch, C., Ballas, M., Wölpl, A., Friedrich, W. Transplantation (1992)
- Enhancement of endothelial cell migration and in vitro tube formation by TAP20, a novel beta 5 integrin-modulating, PKC theta-dependent protein. Tang, S., Gao, Y., Ware, J.A. J. Cell Biol. (1999)
- Integrin alpha v beta 3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor alpha 5 beta 1. Blystone, S.D., Graham, I.L., Lindberg, F.P., Brown, E.J. J. Cell Biol. (1994)
- Growth of primary T-cell non-Hodgkin's lymphomata in SCID-hu mice: requirement for a human lymphoid microenvironment. Waller, E.K., Kamel, O.W., Cleary, M.L., Majumdar, A.S., Schick, M.R., Lieberman, M., Weissman, I.L. Blood (1991)
- Increased expression levels of integrin alphavbeta5 on scleroderma fibroblasts. Asano, Y., Ihn, H., Yamane, K., Kubo, M., Tamaki, K. Am. J. Pathol. (2004)