Gene Review:
Meis1 - Meis homeobox 1
Mus musculus
Synonyms:
C530044H18Rik, Evi8, Homeobox protein Meis1, Myeloid ecotropic viral integration site 1
- Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation. Mamo, A., Krosl, J., Kroon, E., Bijl, J., Thompson, A., Mayotte, N., Girard, S., Bisaillon, R., Beslu, N., Featherstone, M., Sauvageau, G. Blood (2006)
- Identification of a new family of Pbx-related homeobox genes. Nakamura, T., Jenkins, N.A., Copeland, N.G. Oncogene (1996)
- The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo. Azcoitia, V., Aracil, M., Martínez-A, C., Torres, M. Dev. Biol. (2005)
- Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4 : 11) abnormality. Rozovskaia, T., Feinstein, E., Mor, O., Foa, R., Blechman, J., Nakamura, T., Croce, C.M., Cimino, G., Canaani, E. Oncogene (2001)
- Induction of tolerance to immunogenic tumor antigens associated with lymphomagenesis in HOX11 transgenic mice. Rosic-Kablar, S., Chan, K., Reis, M.D., Dubé, I.D., Hough, M.R. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype. Ferretti, E., Villaescusa, J.C., Di Rosa, P., Fernandez-Diaz, L.C., Longobardi, E., Mazzieri, R., Miccio, A., Micali, N., Selleri, L., Ferrari, G., Blasi, F. Mol. Cell. Biol. (2006)
- Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1. Pineault, N., Buske, C., Feuring-Buske, M., Abramovich, C., Rosten, P., Hogge, D.E., Aplan, P.D., Humphries, R.K. Blood (2003)
- Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression. Calvo, K.R., Sykes, D.B., Pasillas, M., Kamps, M.P. Mol. Cell. Biol. (2000)
- Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins. Chang, C.P., Jacobs, Y., Nakamura, T., Jenkins, N.A., Copeland, N.G., Cleary, M.L. Mol. Cell. Biol. (1997)
- Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes. Fujino, T., Yamazaki, Y., Largaespada, D.A., Jenkins, N.A., Copeland, N.G., Hirokawa, K., Nakamura, T. Exp. Hematol. (2001)
- Expression of Meis and Pbx genes and their protein products in the developing telencephalon: implications for regional differentiation. Toresson, H., Parmar, M., Campbell, K. Mech. Dev. (2000)
- Evolutionary divergence of vertebrate Hoxb2 expression patterns and transcriptional regulatory loci. Scemama, J.L., Hunter, M., McCallum, J., Prince, V., Stellwag, E. J. Exp. Zool. (2002)
- c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells. Hess, J.L., Bittner, C.B., Zeisig, D.T., Bach, C., Fuchs, U., Borkhardt, A., Frampton, J., Slany, R.K. Blood (2006)
- 5' hox genes and meis 1, a hox-DNA binding cofactor, are expressed in the adult mouse epididymis. Bomgardner, D., Hinton, B.T., Turner, T.T. Biol. Reprod. (2003)