Gene Review:
Oxtr - oxytocin receptor
Mus musculus
Synonyms:
OT-R, OTR, Oxytocin receptor
Evans,
Forrest-Owen,
McArdle,
Olazábal,
Young,
Arend,
Smart,
Briggs,
Bussolati,
Chinol,
Chini,
Nacca,
Cassoni,
Paganelli,
Mantella,
Vollmer,
Li,
Amico,
Douglas,
Brunton,
Bosch,
Russell,
Neumann,
Amico,
Vollmer,
Karam,
Lee,
Li,
Koenig,
McCarthy,
Kaluz,
Kaluzova,
Flint,
Paquin,
Danalache,
Jankowski,
McCann,
Gutkowska,
Lim,
Murphy,
Young,
Patisaul,
Scordalakes,
Young,
Rissman,
Siebel,
Gehring,
Reytomas,
Parry,
Kubota,
Kimura,
Hashimoto,
Tokugawa,
Nobunaga,
Azuma,
Saji,
Murata,
- Oxytocin inhibits the progression of human ovarian carcinoma cells in vitro and in vivo. Morita, T., Shibata, K., Kikkawa, F., Kajiyama, H., Ino, K., Mizutani, S. Int. J. Cancer (2004)
- Oxytocin receptor within the breast: biological function and distribution. Sapino, A., Cassoni, P., Stella, A., Bussolati, G. Anticancer Res. (1998)
- 111In-labeled 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid-lys(8)-vasotocin: a new powerful radioligand for oxytocin receptor-expressing tumors. Bussolati, G., Chinol, M., Chini, B., Nacca, A., Cassoni, P., Paganelli, G. Cancer Res. (2001)
- Neurohypophysial receptor gene expression by thymic T cell subsets and thymic T cell lymphoma cell lines. Hansenne, I., Rasier, G., Charlet-Renard, C.h., DeFresne, M.P., Greimers, R., Breton, C., Legros, J.J., Geenen, V., Martens, H. Clin. Dev. Immunol. (2004)
- Expression of the oxytocin receptor in clinical human breast cancer tissues. Ito, I., Kimura, T., Wakasugi, E., Takeda, T., Kobayashi, T., Shimano, T., Kubota, Y., Makino, Y., Azuma, C., Saji, F. Adv. Exp. Med. Biol. (1995)
- Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice. Takayanagi, Y., Yoshida, M., Bielsky, I.F., Ross, H.E., Kawamata, M., Onaka, T., Yanagisawa, T., Kimura, T., Matzuk, M.M., Young, L.J., Nishimori, K. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Ventral striatopallidal oxytocin and vasopressin V1a receptors in the monogamous prairie vole (Microtus ochrogaster). Lim, M.M., Murphy, A.Z., Young, L.J. J. Comp. Neurol. (2004)
- Species and individual differences in juvenile female alloparental care are associated with oxytocin receptor density in the striatum and the lateral septum. Olazábal, D.E., Young, L.J. Hormones and behavior. (2006)
- Oxytocin induces differentiation of P19 embryonic stem cells to cardiomyocytes. Paquin, J., Danalache, B.A., Jankowski, M., McCann, S.M., Gutkowska, J. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes. Matsuura, K., Nagai, T., Nishigaki, N., Oyama, T., Nishi, J., Wada, H., Sano, M., Toko, H., Akazawa, H., Sato, T., Nakaya, H., Kasanuki, H., Komuro, I. J. Biol. Chem. (2004)
- Inhibition of oxytocin receptor and estrogen receptor-alpha expression, but not relaxin receptors (LGR7), in the myometrium of late pregnant relaxin gene knockout mice. Siebel, A.L., Gehring, H.M., Reytomas, I.G., Parry, L.J. Endocrinology (2003)
- Mapping oxytocin receptor gene expression in the mouse brain and mammary gland using an oxytocin receptor-LacZ reporter mouse. Gould, B.R., Zingg, H.H. Neuroscience (2003)
- Oxytocin, but not oxytocin receptor, is rRegulated by oestrogen receptor beta in the female mouse hypothalamus. Patisaul, H.B., Scordalakes, E.M., Young, L.J., Rissman, E.F. J. Neuroendocrinol. (2003)
- The differential coupling of oxytocin receptors to uterine contractions in murine estrous cycle. Kawamata, M., Tonomura, Y., Kimura, T., Yanagisawa, T., Nishimori, K. Biochem. Biophys. Res. Commun. (2004)
- Oxytocin receptor-mediated activation of phosphoinositidase C and elevation of cytosolic calcium in the gonadotrope-derived alphaT3-1 cell line. Evans, J.J., Forrest-Owen, W., McArdle, C.A. Endocrinology (1997)
- Oxytocin modulates the onset of murine parturition by competing ovarian and uterine effects. Imamura, T., Luedke, C.E., Vogt, S.K., Muglia, L.J. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2000)
- Estrogen receptor alpha is essential for induction of oxytocin receptor by estrogen. Young, L.J., Wang, Z., Donaldson, R., Rissman, E.F. Neuroreport (1998)
- Female oxytocin-deficient mice display enhanced anxiety-related behavior. Mantella, R.C., Vollmer, R.R., Li, X., Amico, J.A. Endocrinology (2003)
- Structure and expression of the mouse oxytocin receptor gene. Kubota, Y., Kimura, T., Hashimoto, K., Tokugawa, Y., Nobunaga, K., Azuma, C., Saji, F., Murata, Y. Mol. Cell. Endocrinol. (1996)
- Centrally administered oxytocin elicits exaggerated grooming in oxytocin null mice. Amico, J.A., Vollmer, R.R., Karam, J.R., Lee, P.R., Li, X., Koenig, J.I., McCarthy, M.M. Pharmacol. Biochem. Behav. (2004)
- Oxytocin, vasopressin, and the neuroendocrine basis of pair bond formation. Insel, T.R., Winslow, J.T., Wang, Z., Young, L.J. Adv. Exp. Med. Biol. (1998)
- Metanephric rat-mouse chimeras to study cell lineage of the nephron. Arend, L.J., Smart, A., Briggs, J.P. Dev. Genet. (1999)
- Neuroendocrine responses to stress in mice: hyporesponsiveness in pregnancy and parturition. Douglas, A.J., Brunton, P.J., Bosch, O.J., Russell, J.A., Neumann, I.D. Endocrinology (2003)
- Ontogenesis and functional aspects of oxytocin and vasopressin gene expression in the thymus network. Hansenne, I., Rasier, G., Péqueux, C., Brilot, F., Renard, C.h., Breton, C., Greimers, R., Legros, J.J., Geenen, V., Martens, H.J. J. Neuroimmunol. (2005)
- Oxytocin receptors in brain cortical regions are reduced in haploinsufficient (+/-) reeler mice. Liu, W., Pappas, G.D., Carter, C.S. Neurol. Res. (2005)
- Failure of parturition in mice lacking the prostaglandin F receptor. Sugimoto, Y., Yamasaki, A., Segi, E., Tsuboi, K., Aze, Y., Nishimura, T., Oida, H., Yoshida, N., Tanaka, T., Katsuyama, M., Hasumoto, K., Murata, T., Hirata, M., Ushikubi, F., Negishi, M., Ichikawa, A., Narumiya, S. Science (1997)
- The comparative distribution of forebrain receptors for neurohypophyseal peptides in monogamous and polygamous mice. Insel, T.R., Gelhard, R., Shapiro, L.E. Neuroscience (1991)
- Heterogeneity in the third intracytoplasmic region of the oxytocin receptor-encoding gene. Kaluz, S., Kaluzova, M., Flint, A.P. Gene (1996)