Gene Review:
Ly6a - lymphocyte antigen 6 complex, locus A
Mus musculus
Synonyms:
Ly-6A.2, Ly-6A.2/Ly-6E.1, Ly-6A/E, Ly-6E.1, Ly6, ...
- Cloning of the complete Ly-6E.1 gene and identification of DNase I hypersensitive sites corresponding to expression in hematopoietic cells. Sinclair, A.M., Dzierzak, E.A. Blood (1993)
- The differentiation antigen Ly-6E.1 is expressed in mouse metastatic tumor cell lines. Cohn, M.A., Kramerov, D., Hulgaard, E.F., Lukanidin, E.M. FEBS Lett. (1997)
- Functional and phenotypic analysis of thymocytes in SCID mice. Evidence for functional response transitions before and after the SCID arrest point. Rothenberg, E.V., Chen, D., Diamond, R.A. J. Immunol. (1993)
- E mu-bcl-2 transgene facilitates spontaneous transformation of early pre-B and immunoglobulin-secreting cells but not T cells. Strasser, A., Harris, A.W., Cory, S. Oncogene (1993)
- Dual roles of telomerase in cardiac protection and repair. Schneider, M.D. Novartis Found. Symp. (2006)
- Gene gun-mediated IL-12 gene therapy induces antitumor effects in the absence of toxicity: a direct comparison with systemic IL-12 protein therapy. Rakhmilevich, A.L., Timmins, J.G., Janssen, K., Pohlmann, E.L., Sheehy, M.J., Yang, N.S. J. Immunother. (1999)
- Phenotypic plasticity of T cell progenitors upon exposure to Notch ligands. Krueger, A., Garbe, A.I., von Boehmer, H. J. Exp. Med. (2006)
- TAP, a novel T cell-activating protein involved in the stimulation of MHC-restricted T lymphocytes. Rock, K.L., Yeh, E.T., Gramm, C.F., Haber, S.I., Reiser, H., Benacerraf, B. J. Exp. Med. (1986)
- Long-term extensive expansion of mouse hepatic stem/progenitor cells in a novel serum-free culture system. Tsuchiya, A., Heike, T., Fujino, H., Shiota, M., Umeda, K., Yoshimoto, M., Matsuda, Y., Ichida, T., Aoyagi, Y., Nakahata, T. Gastroenterology (2005)
- The human E48 antigen, highly homologous to the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion. Brakenhoff, R.H., Gerretsen, M., Knippels, E.M., van Dijk, M., van Essen, H., Weghuis, D.O., Sinke, R.J., Snow, G.B., van Dongen, G.A. J. Cell Biol. (1995)
- Isolation of a murine Ly-6 cDNA reveals a new multigene family. LeClair, K.P., Palfree, R.G., Flood, P.M., Hammerling, U., Bothwell, A. EMBO J. (1986)
- LY6A/E (SCA-1) expression in the mouse testis. van Bragt, M.P., Ciliberti, N., Stanford, W.L., de Rooij, D.G., van Pelt, A.M. Biol. Reprod. (2005)
- Characterization of Ly-6M, a novel member of the Ly-6 family of hematopoietic proteins. Patterson, J.M., Johnson, M.H., Zimonjic, D.B., Graubert, T.A. Blood (2000)
- Expression of Ly-6, a marker for highly malignant murine tumor cells, is regulated by growth conditions and stress. Treister, A., Sagi-Assif, O., Meer, M., Smorodinsky, N.I., Anavi, R., Golan, I., Meshel, T., Kahana, O., Eshel, R., Katz, B.Z., Shevach, E., Witz, I.P. Int. J. Cancer (1998)
- Roles of Sca-1 in hematopoietic stem/progenitor cell function. Bradfute, S.B., Graubert, T.A., Goodell, M.A. Exp. Hematol. (2005)
- Expression of the hematopoietic stem cell antigen Sca-1 (LY-6A/E) in liver sinusoidal endothelial cells: possible function of Sca-1 in endothelial cells. Luna, G., Paez, J., Cardier, J.E. Stem cells and development. (2004)
- A systemic provascular response in bone marrow to musculoskeletal trauma in mice. Laing, A.J., Dillon, J.P., Condon, E.T., Coffey, J.C., Street, J.T., Wang, J.H., McGuinness, A.J., Redmond, H.P. The Journal of bone and joint surgery. British volume (2007)
- Biosynthesis, glycosylation, and partial N-terminal amino acid sequence of the T-cell-activating protein TAP. Reiser, H., Coligan, J., Benacerraf, B., Rock, K.L. Proc. Natl. Acad. Sci. U.S.A. (1987)
- Overexpressed Ly-6A.2 mediates cell-cell adhesion by binding a ligand expressed on lymphoid cells. Bamezai, A., Rock, K.L. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes. Matsuura, K., Nagai, T., Nishigaki, N., Oyama, T., Nishi, J., Wada, H., Sano, M., Toko, H., Akazawa, H., Sato, T., Nakaya, H., Kasanuki, H., Komuro, I. J. Biol. Chem. (2004)
- TNFalpha and anti-Fas antibodies regulate Ly-6E.1 expression by tumor cells: a possible link between angiogenesis and Ly-6E.1. Sagi-Assif, O., Traister, A., Katz, B.Z., Anavi, R., Eskenasy, M., Witz, I.P. Immunol. Lett. (1996)
- Ly-6A.2 expression regulates antigen-specific CD4+ T cell proliferation and cytokine production. Henderson, S.C., Kamdar, M.M., Bamezai, A. J. Immunol. (2002)
- The T-cell activating protein (TAP) is up-regulated by endogenous IFN-gamma in activated T cells. Dumont, F.J., Palfree, R.G., Fisher, P.A. Immunology (1988)
- Selective up-regulation by interferon-gamma of surface molecules of the Ly-6 complex in resting T cells: the Ly-6A/E and TAP antigens are preferentially enhanced. Dumont, F.J., Dijkmans, R., Palfree, R.G., Boltz, R.D., Coker, L. Eur. J. Immunol. (1987)
- Ly-6A.2 and Ly-6E.1 molecules are antithetical and identical to MALA-1. Palfree, R.G., Dumont, F.J., Hammerling, U. Immunogenetics (1986)
- Isolation and characterization of cDNA clones for the mouse thymocyte B cell antigen (ThB). Gumley, T.P., McKenzie, I.F., Kozak, C.A., Sandrin, M.S. J. Immunol. (1992)
- Mouse hematopoietic stem-cell antigen Sca-1 is a member of the Ly-6 antigen family. van de Rijn, M., Heimfeld, S., Spangrude, G.J., Weissman, I.L. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Expression cloning and characterization of a novel glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein, GPI-HBP1. Ioka, R.X., Kang, M.J., Kamiyama, S., Kim, D.H., Magoori, K., Kamataki, A., Ito, Y., Takei, Y.A., Sasaki, M., Suzuki, T., Sasano, H., Takahashi, S., Sakai, J., Fujino, T., Yamamoto, T.T. J. Biol. Chem. (2003)
- Systemically transferred hematopoietic stem cells home to the subretinal space and express RPE-65 in a mouse model of retinal pigment epithelium damage. Atmaca-Sonmez, P., Li, Y., Yamauchi, Y., Schanie, C.L., Ildstad, S.T., Kaplan, H.J., Enzmann, V. Exp. Eye Res. (2006)