Gene Review:
Umod - uromodulin
Mus musculus
Synonyms:
THP, Tamm-Horsfall glycoprotein, Tamm-Horsfall urinary glycoprotein, Urehd1, Uromodulin, ...
- A transcriptional network in polycystic kidney disease. Gresh, L., Fischer, E., Reimann, A., Tanguy, M., Garbay, S., Shao, X., Hiesberger, T., Fiette, L., Igarashi, P., Yaniv, M., Pontoglio, M. EMBO J. (2004)
- Defective expression of Tamm-Horsfall protein/uromodulin in COX-2-deficient mice increases their susceptibility to urinary tract infections. Dou, W., Thompson-Jaeger, S., Laulederkind, S.J., Becker, J.W., Montgomery, J., Ruiz-Bustos, E., Hasty, D.L., Ballou, L.R., Eastman, P.S., Srichai, B., Breyer, M.D., Raghow, R. Am. J. Physiol. Renal Physiol. (2005)
- Ablation of the Tamm-Horsfall protein gene increases susceptibility of mice to bladder colonization by type 1-fimbriated Escherichia coli. Mo, L., Zhu, X.H., Huang, H.Y., Shapiro, E., Hasty, D.L., Wu, X.R. Am. J. Physiol. Renal Physiol. (2004)
- Tamm-Horsfall protein is a critical renal defense factor protecting against calcium oxalate crystal formation. Mo, L., Huang, H.Y., Zhu, X.H., Shapiro, E., Hasty, D.L., Wu, X.R. Kidney Int. (2004)
- Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice. Bachmann, S., Mutig, K., Bates, J., Welker, P., Geist, B., Gross, V., Luft, F.C., Alenina, N., Bader, M., Thiele, B.J., Prasadan, K., Raffi, H.S., Kumar, S. Am. J. Physiol. Renal Physiol. (2005)
- Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4-dependent mechanism. Säemann, M.D., Weichhart, T., Zeyda, M., Staffler, G., Schunn, M., Stuhlmeier, K.M., Sobanov, Y., Stulnig, T.M., Akira, S., von Gabain, A., von Ahsen, U., Hörl, W.H., Zlabinger, G.J. J. Clin. Invest. (2005)
- Molecular basis of Escherichia coli colonization of the upper urinary tract in BALB/c mice. Gal-Gal pili immunization prevents Escherichia coli pyelonephritis in the BALB/c mouse model of human pyelonephritis. O'Hanley, P., Lark, D., Falkow, S., Schoolnik, G. J. Clin. Invest. (1985)
- Serial microanalysis of renal transcriptomes. Virlon, B., Cheval, L., Buhler, J.M., Billon, E., Doucet, A., Elalouf, J.M. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Detection of novel carbohydrate binding activity of interleukin-1. Tandai-Hiruma, M., Endo, T., Kobata, A. J. Biol. Chem. (1999)
- Adenosinergic modulation of 3alpha-hydroxy-5alpha-pregnan-20-one induced catalepsy in mice. Mandhane, S.N., Khisti, R.T., Chopde, C.T. Psychopharmacology (Berl.) (1999)
- Laser flow cytometric studies on the intracellular accumulation of anthracyclines when combined with heat. Sakaguchi, Y., Maehara, Y., Inutsuka, S., Takahashi, I., Yoshida, M., Emi, Y., Baba, H., Sugimachi, K. Cancer Chemother. Pharmacol. (1994)
- Preparation and pharmacokinetics of pirarubicin loaded dehydration-rehydration vesicles. Kawano, K., Takayama, K., Nagai, T., Maitani, Y. International journal of pharmaceutics. (2003)
- Influence of chlorpromazine on the toxicity of pirarubicin in mice. Maekawa, I., Shibata, H., Furusawa, S., Takayanagi, Y., Sasaki, K. Res. Commun. Chem. Pathol. Pharmacol. (1991)
- Isolation of mouse THP gene promoter and demonstration of its kidney-specific activity in transgenic mice. Zhu, X., Cheng, J., Gao, J., Lepor, H., Zhang, Z.T., Pak, J., Wu, X.R. Am. J. Physiol. Renal Physiol. (2002)
- GP2/THP gene family of self-binding, GPI-anchored proteins forms a cluster at chromosome 7F1 region in mouse genome. Kobayashi, K., Yanagihara, K., Ishiguro, K., Fukuoka, S. Biochem. Biophys. Res. Commun. (2004)
- Thick ascending limb-specific expression of Cre recombinase. Stricklett, P.K., Taylor, D., Nelson, R.D., Kohan, D.E. Am. J. Physiol. Renal Physiol. (2003)
- Steroid withdrawal in the mouse results in anxiogenic effects of 3alpha,5beta-THP: a possible model of premenstrual dysphoric disorder. Smith, S.S., Ruderman, Y., Frye, C., Homanics, G., Yuan, M. Psychopharmacology (Berl.) (2006)
- Brain neurosteroid changes after paroxetine administration in mice. Nechmad, A., Maayan, R., Spivak, B., Ramadan, E., Poyurovsky, M., Weizman, A. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. (2003)
- Axial heterogeneity of vasopressin-receptor subtypes along the human and mouse collecting duct. Carmosino, M., Brooks, H.L., Cai, Q., Davis, L.S., Opalenik, S., Hao, C., Breyer, M.D. Am. J. Physiol. Renal Physiol. (2007)
- The lectin-like interaction between recombinant tumor necrosis factor and uromodulin. Sherblom, A.P., Decker, J.M., Muchmore, A.V. J. Biol. Chem. (1988)
- Metanephric rat-mouse chimeras to study cell lineage of the nephron. Arend, L.J., Smart, A., Briggs, J.P. Dev. Genet. (1999)
- Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a toll-like receptor-4-dependent mechanism. Ratliff, T.L. J. Urol. (2005)
- Assignment of the Tamm-Horsfall protein/uromodulin gene (Umod) to mouse chromosome bands 7F1-F2 and rat chromosome bands 1q36-->q37 by in situ hybridization. Fukuoka, S., Matsuda, Y. Cytogenet. Cell Genet. (1997)
- Renal tubule-specific expression and urinary secretion of human growth hormone: a kidney-based transgenic bioreactor growth. Zhu, X., Cheng, J., Huang, L., Gao, J., Zhang, Z.T., Pak, J., Wu, X.R. Transgenic Res. (2003)