Gene Review:
Ghsr - growth hormone secretagogue receptor
Mus musculus
Synonyms:
C530020I22Rik, GH-releasing peptide receptor, GHRP, GHS-R, Ghrelin receptor, ...
- Is ghrelin a signal for the development of metabolic systems? Grove, K.L., Cowley, M.A. J. Clin. Invest. (2005)
- Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Sun, Y., Wang, P., Zheng, H., Smith, R.G. Proc. Natl. Acad. Sci. U.S.A. (2004)
- GH-releasing peptide-2 increases fat mass in mice lacking NPY: indication for a crucial mediating role of hypothalamic agouti-related protein. Tschöp, M., Statnick, M.A., Suter, T.M., Heiman, M.L. Endocrinology (2002)
- NPY/AgRP neurons are not essential for feeding responses to glucoprivation. Luquet, S., Phillips, C.T., Palmiter, R.D. Peptides (2007)
- Mice lacking ghrelin receptors resist the development of diet-induced obesity. Zigman, J.M., Nakano, Y., Coppari, R., Balthasar, N., Marcus, J.N., Lee, C.E., Jones, J.E., Deysher, A.E., Waxman, A.R., White, R.D., Williams, T.D., Lachey, J.L., Seeley, R.J., Lowell, B.B., Elmquist, J.K. J. Clin. Invest. (2005)
- Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats. Clegg, D.J., Brown, L.M., Zigman, J.M., Kemp, C.J., Strader, A.D., Benoit, S.C., Woods, S.C., Mangiaracina, M., Geary, N. Diabetes (2007)
- Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue receptor/dopamine receptor subtype 1 heterodimers. Jiang, H., Betancourt, L., Smith, R.G. Mol. Endocrinol. (2006)
- Ghrelin differentially affects hepatic and peripheral insulin sensitivity in mice. Heijboer, A.C., van den Hoek, A.M., Parlevliet, E.T., Havekes, L.M., Romijn, J.A., Pijl, H., Corssmit, E.P. Diabetologia (2006)
- Effects of ghrelin on anorexia in tumor-bearing mice with eicosanoid-related cachexia. Wang, W., Andersson, M., Iresjö, B.M., Lönnroth, C., Lundholm, K. Int. J. Oncol. (2006)
- [Trp3, Arg5]-ghrelin(1-5) stimulates growth hormone secretion and food intake via growth hormone secretagogue (GHS) receptor. Ohinata, K., Kobayashi, K., Yoshikawa, M. Peptides (2006)
- Inhibition of adipogenesis by ghrelin. Zhang, W., Zhao, L., Lin, T.R., Chai, B., Fan, Y., Gantz, I., Mulholland, M.W. Mol. Biol. Cell (2004)
- Gastric motor effects of peptide and non-peptide ghrelin agonists in mice in vivo and in vitro. Kitazawa, T., De Smet, B., Verbeke, K., Depoortere, I., Peeters, T.L. Gut (2005)
- Peripheral ghrelin deepens torpor bouts in mice through the arcuate nucleus neuropeptide Y signaling pathway. Gluck, E.F., Stephens, N., Swoap, S.J. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2006)
- IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion. Doi, A., Shono, T., Nishi, M., Furuta, H., Sasaki, H., Nanjo, K. Proc. Natl. Acad. Sci. U.S.A. (2006)
- The mitogenic and antiapoptotic actions of ghrelin in 3T3-L1 adipocytes. Kim, M.S., Yoon, C.Y., Jang, P.G., Park, Y.J., Shin, C.S., Park, H.S., Ryu, J.W., Pak, Y.K., Park, J.Y., Lee, K.U., Kim, S.Y., Lee, H.K., Kim, Y.B., Park, K.S. Mol. Endocrinol. (2004)
- Ghrelin inhibits the development of mouse preimplantation embryos in vitro. Kawamura, K., Sato, N., Fukuda, J., Kodama, H., Kumagai, J., Tanikawa, H., Nakamura, A., Honda, Y., Sato, T., Tanaka, T. Endocrinology (2003)
- Discovery and pharmacological evaluation of growth hormone secretagogue receptor antagonists. Xin, Z., Serby, M.D., Zhao, H., Kosogof, C., Szczepankiewicz, B.G., Liu, M., Liu, B., Hutchins, C.W., Sarris, K.A., Hoff, E.D., Falls, H.D., Lin, C.W., Ogiela, C.A., Collins, C.A., Brune, M.E., Bush, E.N., Droz, B.A., Fey, T.A., Knourek-Segel, V.E., Shapiro, R., Jacobson, P.B., Beno, D.W., Turner, T.M., Sham, H.L., Liu, G. J. Med. Chem. (2006)
- Upregulation of Ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration. Toshinai, K., Mondal, M.S., Nakazato, M., Date, Y., Murakami, N., Kojima, M., Kangawa, K., Matsukura, S. Biochem. Biophys. Res. Commun. (2001)
- Antagonism of ghrelin receptor reduces food intake and body weight gain in mice. Asakawa, A., Inui, A., Kaga, T., Katsuura, G., Fujimiya, M., Fujino, M.A., Kasuga, M. Gut (2003)
- Impact of obesity on the growth hormone axis: evidence for a direct inhibitory effect of hyperinsulinemia on pituitary function. Luque, R.M., Kineman, R.D. Endocrinology (2006)
- Expression analysis of hypothalamic and pituitary components of the growth hormone axis in fasted and streptozotocin-treated neuropeptide Y (NPY)-intact (NPY+/+) and NPY-knockout (NPY-/-) mice. Park, S., Peng, X.D., Frohman, L.A., Kineman, R.D. Neuroendocrinology (2005)
- Oestrogen replacement in vivo rescues the dysfunction of pituitary somatotropes in ovariectomised aromatase knockout mice. Yan, M., Jones, M.E., Hernandez, M., Liu, D., Simpson, E.R., Chen, C. Neuroendocrinology (2005)