Gene Review:
Tnfsf13b - tumor necrosis factor (ligand) superfamily...
Mus musculus
Synonyms:
B-cell-activating factor, BAFF, BLyS, Baff, D8Ertd387e, ...
- Act1, a negative regulator in CD40- and BAFF-mediated B cell survival. Qian, Y., Qin, J., Cui, G., Naramura, M., Snow, E.C., Ware, C.F., Fairchild, R.L., Omori, S.A., Rickert, R.C., Scott, M., Kotzin, B.L., Li, X. Immunity (2004)
- BAFF augments certain Th1-associated inflammatory responses. Sutherland, A.P., Ng, L.G., Fletcher, C.A., Shum, B., Newton, R.A., Grey, S.T., Rolph, M.S., Mackay, F., Mackay, C.R. J. Immunol. (2005)
- Development of nephritis but not sialadenitis in autoimmune-prone BAFF transgenic mice lacking marginal zone B cells. Fletcher, C.A., Sutherland, A.P., Groom, J.R., Batten, M.L., Ng, L.G., Gommerman, J., Mackay, F. Eur. J. Immunol. (2006)
- In vitro and in vivo activation induces BAFF and APRIL expression in B cells. Chu, V.T., Enghard, P., Riemekasten, G., Berek, C. J. Immunol. (2007)
- TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Gross, J.A., Johnston, J., Mudri, S., Enselman, R., Dillon, S.R., Madden, K., Xu, W., Parrish-Novak, J., Foster, D., Lofton-Day, C., Moore, M., Littau, A., Grossman, A., Haugen, H., Foley, K., Blumberg, H., Harrison, K., Kindsvogel, W., Clegg, C.H. Nature (2000)
- An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Schiemann, B., Gommerman, J.L., Vora, K., Cachero, T.G., Shulga-Morskaya, S., Dobles, M., Frew, E., Scott, M.L. Science (2001)
- Immunology. Long live the mature B cell--a baffling mystery resolved. Waldschmidt, T.J., Noelle, R.J. Science (2001)
- Alternative and Classical NF-kappaB Signaling Retain Autoreactive B Cells in the Splenic Marginal Zone and Result in Lupus-like Disease. Enzler, T., Bonizzi, G., Silverman, G.J., Otero, D.C., Widhopf, G.F., Anzelon-Mills, A., Rickert, R.C., Karin, M. Immunity (2006)
- Homeostatic cell-cycle control by BLyS: Induction of cell-cycle entry but not G1/S transition in opposition to p18INK4c and p27Kip1. Huang, X., Di Liberto, M., Cunningham, A.F., Kang, L., Cheng, S., Ely, S., Liou, H.C., Maclennan, I.C., Chen-Kiang, S. Proc. Natl. Acad. Sci. U.S.A. (2004)
- A role for B cell-activating factor of the TNF family in chemically induced autoimmunity. Zheng, Y., Gallucci, S., Gaughan, J.P., Gross, J.A., Monestier, M. J. Immunol. (2005)
- Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice. Rahman, Z.S., Rao, S.P., Kalled, S.L., Manser, T. J. Exp. Med. (2003)
- Extracellular proteinase inhibitor-accelerated apoptosis is associated with B cell activating factor in mammary epithelial cells. Jung, D.J., Bong, J.J., Baik, M. Exp. Cell Res. (2004)
- Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-kappaB activation pathways. Zarnegar, B., He, J.Q., Oganesyan, G., Hoffmann, A., Baltimore, D., Cheng, G. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Activation and accumulation of B cells in TACI-deficient mice. Yan, M., Wang, H., Chan, B., Roose-Girma, M., Erickson, S., Baker, T., Tumas, D., Grewal, I.S., Dixit, V.M. Nat. Immunol. (2001)
- Reactive oxygen species augment B-cell-activating factor expression. Moon, E.Y., Lee, J.H., Oh, S.Y., Ryu, S.K., Kim, H.M., Kwak, H.S., Yoon, W.K. Free Radic. Biol. Med. (2006)
- BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway. Craxton, A., Draves, K.E., Gruppi, A., Clark, E.A. J. Exp. Med. (2005)
- Formation of virus-like clusters is an intrinsic property of the tumor necrosis factor family member BAFF (B cell activating factor). Cachero, T.G., Schwartz, I.M., Qian, F., Day, E.S., Bossen, C., Ingold, K., Tardivel, A., Krushinskie, D., Eldredge, J., Silvian, L., Lugovskoy, A., Farrington, G.K., Strauch, K., Schneider, P., Whitty, A. Biochemistry (2006)
- Comparison of soluble decoy IgG fusion proteins of BAFF-R and BCMA as antagonists for BAFF. Pelletier, M., Thompson, J.S., Qian, F., Bixler, S.A., Gong, D., Cachero, T., Gilbride, K., Day, E., Zafari, M., Benjamin, C., Gorelik, L., Whitty, A., Kalled, S.L., Ambrose, C., Hsu, Y.M. J. Biol. Chem. (2003)
- BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells. Claudio, E., Brown, K., Park, S., Wang, H., Siebenlist, U. Nat. Immunol. (2002)
- NF-kappa B1 p50 is required for BLyS attenuation of apoptosis but dispensable for processing of NF-kappa B2 p100 to p52 in quiescent mature B cells. Hatada, E.N., Do, R.K., Orlofsky, A., Liou, H.C., Prystowsky, M., MacLennan, I.C., Caamano, J., Chen-Kiang, S. J. Immunol. (2003)
- B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation. Shulga-Morskaya, S., Dobles, M., Walsh, M.E., Ng, L.G., MacKay, F., Rao, S.P., Kalled, S.L., Scott, M.L. J. Immunol. (2004)
- Regulation of B-cell survival by BAFF-dependent PKCdelta-mediated nuclear signalling. Mecklenbräuker, I., Kalled, S.L., Leitges, M., Mackay, F., Tarakhovsky, A. Nature (2004)
- BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2. Kayagaki, N., Yan, M., Seshasayee, D., Wang, H., Lee, W., French, D.M., Grewal, I.S., Cochran, A.G., Gordon, N.C., Yin, J., Starovasnik, M.A., Dixit, V.M. Immunity (2002)
- B cell maturation antigen, the receptor for a proliferation-inducing ligand and B cell-activating factor of the TNF family, induces antigen presentation in B cells. Yang, M., Hase, H., Legarda-Addison, D., Varughese, L., Seed, B., Ting, A.T. J. Immunol. (2005)
- APRIL-deficient mice have normal immune system development. Varfolomeev, E., Kischkel, F., Martin, F., Seshasayee, D., Wang, H., Lawrence, D., Olsson, C., Tom, L., Erickson, S., French, D., Schow, P., Grewal, I.S., Ashkenazi, A. Mol. Cell. Biol. (2004)
- Expression and function of TNF family member B cell-activating factor in the development of autoimmune arthritis. Zhang, M., Ko, K.H., Lam, Q.L., Lo, C.K., Srivastava, G., Zheng, B., Lau, Y.L., Lu, L. Int. Immunol. (2005)
- Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis. Magliozzi, R., Columba-Cabezas, S., Serafini, B., Aloisi, F. J. Neuroimmunol. (2004)
- BLyS--an essential survival factor for B cells: basic biology, links to pathology and therapeutic target. Baker, K.P. Autoimmunity reviews. (2004)
- Rapid and specific targeting of 125I-labeled B lymphocyte stimulator to lymphoid tissues and B cell tumors in mice. Riccobene, T.A., Miceli, R.C., Lincoln, C., Knight, Y., Meadows, J., Stabin, M.G., Sung, C. J. Nucl. Med. (2003)