Gene Review:
NOS2 - nitric oxide synthase 2, inducible
Bos taurus
Synonyms:
NOS2A, iNOS
- Endothelial cells inhibit NO generation by vascular smooth muscle cells. Role of transforming growth factor-beta. López Farré, A., Mosquera, J.R., Sánchez de Miguel, L., Millás, I., de Frutos, T., Montón, M., Sierra, M.P., Riesco, A., Casado, S. Arterioscler. Thromb. Vasc. Biol. (1996)
- Diabetes-induced nitrative stress in the retina, and correction by aminoguanidine. Du, Y., Smith, M.A., Miller, C.M., Kern, T.S. J. Neurochem. (2002)
- Underlying disease stress augments plasma and tissue adrenomedullin (AM) responses to endotoxin: colocalized increases in AM and inducible nitric oxide synthase within pancreatic islets. Elsasser, T.H., Sartin, J.L., Martínez, A., Kahl, S., Montuenga, L., Pío, R., Fayer, R., Miller, M.J., Cuttitta, F. Endocrinology (1999)
- Aspirin inhibits inducible nitric oxide synthase expression and tumour necrosis factor-alpha release by cultured smooth muscle cells. Sánchez de Miguel, L., de Frutos, T., González-Fernández, F., del Pozo, V., Lahoz, C., Jiménez, A., Rico, L., García, R., Aceituno, E., Millás, I., Gómez, J., Farré, J., Casado, S., López-Farré, A. Eur. J. Clin. Invest. (1999)
- Induction of nitric oxide production by bovine alveolar macrophages in response to Pasteurella haemolytica A1. Yoo, H.S., Rutherford, M.S., Maheswaran, S.K., Srinand, S., Ames, T.R. Microb. Pathog. (1996)
- Mechanisms underlying growth hormone effects in augmenting nitric oxide production and protein tyrosine nitration during endotoxin challenge. Elsasser, T.H., Kahl, S., MacLeod, C., Nicholson, B., Sartin, J.L., Li, C. Endocrinology (2004)
- Tumor cell apoptosis by irradiation-induced nitric oxide production in vascular endothelium. Hirakawa, M., Oike, M., Masuda, K., Ito, Y. Cancer Res. (2002)
- Proline-rich tyrosine kinase 2 and Src kinase signaling transduce monosodium urate crystal-induced nitric oxide production and matrix metalloproteinase 3 expression in chondrocytes. Liu, R., Lioté, F., Rose, D.M., Merz, D., Terkeltaub, R. Arthritis Rheum. (2004)
- Staphylococcus aureus stimulates inducible nitric oxide synthase in articular cartilage. Jang, D., Williams, R.J., Wang, M.X., Wei, A.Q., Murrell, G.A. Arthritis Rheum. (1999)
- Role of interferon regulatory factor-1 and mitogen-activated protein kinase pathways in the induction of nitric oxide synthase-2 in retinal pigmented epithelial cells. Faure, V., Hecquet, C., Courtois, Y., Goureau, O. J. Biol. Chem. (1999)
- SB 203580 inhibits p38 mitogen-activated protein kinase, nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes. Badger, A.M., Cook, M.N., Lark, M.W., Newman-Tarr, T.M., Swift, B.A., Nelson, A.H., Barone, F.C., Kumar, S. J. Immunol. (1998)
- Minocycline inhibits the production of inducible nitric oxide synthase in articular chondrocytes. Sadowski, T., Steinmeyer, J. J. Rheumatol. (2001)
- Are free radicals responsible for endothelial cell killing of Staphylococcus aureus? Zhang, B., Centra, M., Cao, G.L., Ratych, R.E., Domachowske, J.B., Malech, H.L., Rosen, G.M. Immunol. Lett. (1997)
- Induction of nitric oxide synthase in bovine mononuclear phagocytes is differentiation stage-dependent. Jungi, T.W., Thöny, M., Brcic, M., Adler, B., Pauli, U., Peterhans, E. Immunobiology (1996)
- Inhibition of inducible nitric oxide synthase expression by interferons alpha and beta in bovine retinal pigmented epithelial cells. Faure, V., Courtois, Y., Goureau, O. J. Biol. Chem. (1997)
- Oxygen-glucose deprivation induces inducible nitric oxide synthase and nitrotyrosine expression in cerebral endothelial cells. Xu, J., He, L., Ahmed, S.H., Chen, S.W., Goldberg, M.P., Beckman, J.S., Hsu, C.Y. Stroke (2000)
- Inhibition of interleukin-1-induced proteoglycan degradation and nitric oxide production in bovine articular cartilage/chondrocyte cultures by the natural product, hymenialdisine. Badger, A.M., Cook, M.N., Swift, B.A., Newman-Tarr, T.M., Gowen, M., Lark, M. J. Pharmacol. Exp. Ther. (1999)
- Gene transfer with inducible nitric oxide synthase decreases production of urea by arginase in pulmonary arterial endothelial cells. Stanley, K.P., Chicoine, L.G., Young, T.L., Reber, K.M., Lyons, C.R., Liu, Y., Nelin, L.D. Am. J. Physiol. Lung Cell Mol. Physiol. (2006)
- Involvement of pro-inflammatory cytokines, mediators of inflammation, and basic fibroblast growth factor in prostaglandin F2alpha-induced luteolysis in bovine corpus luteum. Neuvians, T.P., Schams, D., Berisha, B., Pfaffl, M.W. Biol. Reprod. (2004)
- Region-specific expression of nitric oxide synthases in the bovine oviduct during the oestrous cycle and in vitro. Ulbrich, S.E., Rehfeld, S., Bauersachs, S., Wolf, E., Rottmayer, R., Hiendleder, S., Vermehren, M., Sinowatz, F., Meyer, H.H., Einspanier, R. J. Endocrinol. (2006)
- Expression of inducible nitric oxide synthase in bovine corneal endothelial cells and keratocytes in vitro after lipopolysaccharide and cytokines stimulation. Dighiero, P., Behar-Cohen, F., Courtois, Y., Goureau, O. Invest. Ophthalmol. Vis. Sci. (1997)
- Stimulation of nitric oxide-cyclic guanosine monophosphate pathway in bovine ovarian theca cells by tumor necrosis factor alpha (TNF alpha). Is this pathway implicated in the TNF alpha-induced inhibition of luteinizing hormone-stimulated prorenin production? Brunswig-Spickenheier, B., Mukhopadhyay, A.K. Biol. Reprod. (1997)
- Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes. Ea, H.K., Uzan, B., Rey, C., Lioté, F. Arthritis Res. Ther. (2005)
- Cationic amino acid transport across the blood-brain barrier is mediated exclusively by system y+. O'Kane, R.L., Viña, J.R., Simpson, I., Zaragozá, R., Mokashi, A., Hawkins, R.A. Am. J. Physiol. Endocrinol. Metab. (2006)
- Nitric oxide, an autocrine regulator of wound fibroblast synthetic function. Schäffer, M.R., Efron, P.A., Thornton, F.J., Klingel, K., Gross, S.S., Barbul, A. J. Immunol. (1997)