Gene Review:
IGKC - immunoglobulin kappa constant
Homo sapiens
Synonyms:
HCAK1, IGKCD, Ig kappa chain C region, Km
- Association between Crohn's disease and immunoglobulin heavy chain (Gm) allotypes. Kagnoff, M.F., Brown, R.J., Schanfield, M.S. Gastroenterology (1983)
- Differences in idiopathic inflammatory myopathy phenotypes and genotypes between Mesoamerican Mestizos and North American Caucasians: ethnogeographic influences in the genetics and clinical expression of myositis. Shamim, E.A., Rider, L.G., Pandey, J.P., O'Hanlon, T.P., Jara, L.J., Samayoa, E.A., Burgos-Vargas, R., Vazquez-Mellado, J., Alcocer-Varela, J., Salazar-Paramo, M., Kutzbach, A.G., Malley, J.D., Targoff, I.N., Garcia-De la Torre, I., Miller, F.W. Arthritis Rheum. (2002)
- The intron enhancer of the immunoglobulin kappa gene activates c-myc but does not induce the Burkitt-specific promoter shift. Polack, A., Strobl, L., Feederle, R., Schweizer, M., Koch, E., Eick, D., Wiegand, H., Bornkamm, G.W. Oncogene (1991)
- Immunoglobulin allotypes and immunoglobulin G subclass responses to Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in early-onset periodontitis. Choi, J.I., Ha, M.H., Kim, J.H., Kim, S.J. Infect. Immun. (1996)
- Catalytic hydrolysis of vasoactive intestinal peptide by human autoantibody. Paul, S., Volle, D.J., Beach, C.M., Johnson, D.R., Powell, M.J., Massey, R.J. Science (1989)
- Selective chemical catalysis by an antibody. Pollack, S.J., Jacobs, J.W., Schultz, P.G. Science (1986)
- Correlation of the Km(1) immunoglobulin allotype with anti-polysaccharide antibodies in Caucasian adults. Ambrosino, D.M., Barrus, V.A., DeLange, G.G., Siber, G.R. J. Clin. Invest. (1986)
- Radioimmune determination of hypoxanthine phosphoribosyltransferase crossreacting material in erythrocytes of Lesch-Nyhan patients. Ghangas, G.S., Milman, G. Proc. Natl. Acad. Sci. U.S.A. (1975)
- Characterization of the human immunoglobulin kappa gene 3' enhancer: functional importance of three motifs that demonstrate B-cell-specific in vivo footprints. Judde, J.G., Max, E.E. Mol. Cell. Biol. (1992)
- Hormonal and chemical influences on the expression of class 2 aldehyde dehydrogenases in rat H4IIEC3 and human HuH7 hepatoma cells. Crabb, D.W., Stewart, M.J., Xiao, Q. Alcohol. Clin. Exp. Res. (1995)
- Comparative study of human steroid 5alpha-reductase isoforms in prostate and female breast skin tissues: sensitivity to inhibition by finasteride and epristeride. Ranjan, M., Diffley, P., Stephen, G., Price, D., Walton, T.J., Newton, R.P. Life Sci. (2002)
- Residual disease in B-cell chronic lymphocytic leukemia patients and prognostic value. Lenormand, B., Bizet, M., Fruchart, C., Tilly, H., Daliphard, S., Thouret, F., Canipel, C., Callat, M.P., Piguet, H., Lefranc, M.P. Leukemia (1994)
- Six loci mapped on to human chromosome 2p are assigned to sheep chromosome 3p. Broad, T.E., Burkin, D.J., Cambridge, L.M., Jones, C., Lewis, P.E., Morse, H.G., Geyer, D., Pearce, P.D., Ansari, H.A., Maher, D.W. Anim. Genet. (1995)
- High Km soluble 5'-nucleotidase from human placenta. Properties and allosteric regulation by IMP and ATP. Spychała, J., Madrid-Marina, V., Fox, I.H. J. Biol. Chem. (1988)
- Association of immunoglobulin Km and Gm allotypes with specific antinuclear antibodies and disease susceptibility among connective tissue disease patients. Hoffman, R.W., Sharp, G.C., Irvin, W.S., Anderson, S.K., Hewett, J.E., Pandey, J.P. Arthritis Rheum. (1991)
- Identification of a novel substitution in the constant region of a gene coding for an amyloidogenic kappa1 light chain. Wally, J., Kica, G., Zhang, Y., Ericsson, T., Connors, L.H., Benson, M.D., Liepnieks, J.J., Murray, J., Skinner, M., Comenzo, R.L. Biochim. Biophys. Acta (1999)
- Cyclic adenosine 3':5'-monophosphate phosphodiesterase. Distinct forms in human lymphocytes and monocytes. Thompson, W.J., Ross, C.P., Pledger, W.J., Strada, S.J., Banner, R.L., Hersh, E.M. J. Biol. Chem. (1976)
- 7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes. Yamazaki, H., Inoue, K., Mimura, M., Oda, Y., Guengerich, F.P., Shimada, T. Biochem. Pharmacol. (1996)
- Km mutant of acid alpha-glucosidase in a case of cardiomyopathy without signs of skeletal muscle involvement. Suzuki, Y., Tsuji, A., Omura, K., Nakamura, G., Awa, S., Kroos, M., Reuser, A.J. Clin. Genet. (1988)
- Purification and properties of alpha-D-mannose:beta-1,2-N-acetylglucosaminyl-transferases and alpha-D-mannosidases from human adenocarcinoma. Chandrasekaran, E.V., Davila, M., Nixon, D., Mendicino, J. Cancer Res. (1984)
- Optimized assay for thymidine kinase and its application to the detection of antibodies against herpes simplex virus type 1- and 2-induced thymidine kinase. Gronowitz, J.S., Källander, C.F. Infect. Immun. (1980)
- Isolation and characterization of cancer-associated galactosyltransferase isoenzyme. Ram, B.P., Munjal, D.D. Clin. Chem. (1984)
- Lactate transport in skeletal muscle - role and regulation of the monocarboxylate transporter. Juel, C., Halestrap, A.P. J. Physiol. (Lond.) (1999)
- A linkage study of acrokeratoelastoidosis. Possible mapping to chromosome 2. Greiner, J., Krüger, J., Palden, L., Jung, E.G., Vogel, F. Hum. Genet. (1983)
- Detection of illegitimate rearrangements within the immunoglobulin light chain loci in B cell malignancies using end sequenced probes. Poulsen, T.S., Silahtaroglu, A.N., Gisselø, C.G., Tommerup, N., Johnsen, H.E. Leukemia (2002)
- Marsupial light chains: IGK with four V families in the opossum Monodelphis domestica. Miller, R.D., Bergemann, E.R., Rosenberg, G.H. Immunogenetics (1999)
- Km genotyping using polymerase chain reaction-allele specific oligonucleotide in Koreans. Park, K.S., Nam, J.H., Kim, M.Y. Mol. Cells (1997)
- Kappa marker typing with high-performance liquid chromatography: identification of kappa marker specific tryptic peptide from the kappa light chain of immunoglobulin G. Iida, R., Yasuda, T., Nadano, D., Takeshita, H., Kishi, K. J. Chromatogr. (1993)
- Soluble "high Km" 5'-nucleotidase activity in human T- and B-lymphoblasts: isolation and some properties. Madrid-Marina, V. Int. J. Biochem. (1990)
- Allotypes and gynecological cancer. Hitoglou-Hadji, S., Makedos, G., Papanicolaou, A., Dozi-Vasiliadou, I. Clinical and experimental obstetrics & gynecology. (1997)