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Chemical Compound Review

CHEMBL146972     2-aminoethoxyphosphonic acid

Synonyms: CHEBI:17553, P0503_SIGMA, HMDB00224, ANW-43177, GEO-00129, ...
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Disease relevance of ethanolamine phosphate


Psychiatry related information on ethanolamine phosphate


High impact information on ethanolamine phosphate


Chemical compound and disease context of ethanolamine phosphate


Biological context of ethanolamine phosphate


Anatomical context of ethanolamine phosphate


Associations of ethanolamine phosphate with other chemical compounds


Gene context of ethanolamine phosphate


Analytical, diagnostic and therapeutic context of ethanolamine phosphate


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  2. Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili. Hegge, F.T., Hitchen, P.G., Aas, F.E., Kristiansen, H., Løvold, C., Egge-Jacobsen, W., Panico, M., Leong, W.Y., Bull, V., Virji, M., Morris, H.R., Dell, A., Koomey, M. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  3. Regulation of the cytidine phospholipid pathways in human cancer cells and effects of 1-beta-D-arabinofuranosylcytosine: a noninvasive 31P nuclear magnetic resonance study. Daly, P.F., Zugmaier, G., Sandler, D., Carpen, M., Myers, C.E., Cohen, J.S. Cancer Res. (1990) [Pubmed]
  4. Identification of sn-glycero-1-phosphate and phosphoethanolamine residues linked to the membrane-derived Oligosaccharides of Escherichia coli. Kennedy, E.P., Rumley, M.K., Schulman, H., Van Golde, L.M. J. Biol. Chem. (1976) [Pubmed]
  5. Lipid A modifications in polymyxin-resistant Salmonella typhimurium: PMRA-dependent 4-amino-4-deoxy-L-arabinose, and phosphoethanolamine incorporation. Zhou, Z., Ribeiro, A.A., Lin, S., Cotter, R.J., Miller, S.I., Raetz, C.R. J. Biol. Chem. (2001) [Pubmed]
  6. Ethanolamine and phosphoethanolamine inhibit mitochondrial function in vitro: implications for mitochondrial dysfunction hypothesis in depression and bipolar disorder. Modica-Napolitano, J.S., Renshaw, P.F. Biol. Psychiatry (2004) [Pubmed]
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  8. Phosphatidylethanolamine is the donor of the terminal phosphoethanolamine group in trypanosome glycosylphosphatidylinositols. Menon, A.K., Eppinger, M., Mayor, S., Schwarz, R.T. EMBO J. (1993) [Pubmed]
  9. Structure and dynamics of the phosphatidylcholine and the phosphatidylethanolamine head group in L-M fibroblasts as studied by deuterium nuclear magnetic resonance. Scherer, P.G., Seelig, J. EMBO J. (1987) [Pubmed]
  10. Silencing of phosphoethanolamine N-methyltransferase results in temperature-sensitive male sterility and salt hypersensitivity in Arabidopsis. Mou, Z., Wang, X., Fu, Z., Dai, Y., Han, C., Ouyang, J., Bao, F., Hu, Y., Li, J. Plant Cell (2002) [Pubmed]
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  12. Ca2+-induced phosphoethanolamine transfer to the outer 3-deoxy-D-manno-octulosonic acid moiety of Escherichia coli lipopolysaccharide. A novel membrane enzyme dependent upon phosphatidylethanolamine. Kanipes, M.I., Lin, S., Cotter, R.J., Raetz, C.R. J. Biol. Chem. (2001) [Pubmed]
  13. Requirement of PIG-F and PIG-O for transferring phosphoethanolamine to the third mannose in glycosylphosphatidylinositol. Hong, Y., Maeda, Y., Watanabe, R., Inoue, N., Ohishi, K., Kinoshita, T. J. Biol. Chem. (2000) [Pubmed]
  14. Identification of a gene (lpt-3) required for the addition of phosphoethanolamine to the lipopolysaccharide inner core of Neisseria meningitidis and its role in mediating susceptibility to bactericidal killing and opsonophagocytosis. Mackinnon, F.G., Cox, A.D., Plested, J.S., Tang, C.M., Makepeace, K., Coull, P.A., Wright, J.C., Chalmers, R., Hood, D.W., Richards, J.C., Moxon, E.R. Mol. Microbiol. (2002) [Pubmed]
  15. In vivo, ex vivo, and in vitro one- and two-dimensional nuclear magnetic resonance spectroscopy of an intracerebral glioma in rat brain: assignment of resonances. Rémy, C., Arús, C., Ziegler, A., Lai, E.S., Moreno, A., Le Fur, Y., Décorps, M. J. Neurochem. (1994) [Pubmed]
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  17. Pseudohypophosphatasia: aberrant localization and substrate specificity of alkaline phosphatase in cultured skin fibroblasts. Fedde, K.N., Cole, D.E., Whyte, M.P. Am. J. Hum. Genet. (1990) [Pubmed]
  18. Evidence of the presence of a specific ATPase responsible for ATP-initiated calcification by matrix vesicles isolated from cartilage and bone. Hsu, H.H., Anderson, H.C. J. Biol. Chem. (1996) [Pubmed]
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  20. Deep zone articular chondrocytes in vitro express genes that show specific changes with mineralization. Sun, Y., Kandel, R. J. Bone Miner. Res. (1999) [Pubmed]
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  25. Murine mammary tumor response to hyperthermia and radiotherapy evaluated by in vivo 31P-nuclear magnetic resonance spectroscopy. Sijens, P.E., Bovée, W.M., Seijkens, D., Koole, P., Los, G., van Rijssel, R.H. Cancer Res. (1987) [Pubmed]
  26. Choline regulates phosphatidylethanolamine biosynthesis in isolated hamster heart. Zelinski, T.A., Choy, P.C. J. Biol. Chem. (1982) [Pubmed]
  27. Lipid A modifications characteristic of Salmonella typhimurium are induced by NH4VO3 in Escherichia coli K12. Detection of 4-amino-4-deoxy-L-arabinose, phosphoethanolamine and palmitate. Zhou, Z., Lin, S., Cotter, R.J., Raetz, C.R. J. Biol. Chem. (1999) [Pubmed]
  28. Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositol. Hong, Y., Maeda, Y., Watanabe, R., Ohishi, K., Mishkind, M., Riezman, H., Kinoshita, T. J. Biol. Chem. (1999) [Pubmed]
  29. Glycosylphosphatidylinositol biosynthesis defects in Gpi11p- and Gpi13p-deficient yeast suggest a branched pathway and implicate gpi13p in phosphoethanolamine transfer to the third mannose. Taron, C.H., Wiedman, J.M., Grimme, S.J., Orlean, P. Mol. Biol. Cell (2000) [Pubmed]
  30. Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component. Bottazzi, B., Vouret-Craviari, V., Bastone, A., De Gioia, L., Matteucci, C., Peri, G., Spreafico, F., Pausa, M., D'Ettorre, C., Gianazza, E., Tagliabue, A., Salmona, M., Tedesco, F., Introna, M., Mantovani, A. J. Biol. Chem. (1997) [Pubmed]
  31. Isolation and characterization of ECT1 gene encoding CTP: phosphoethanolamine cytidylyltransferase of Saccharomyces cerevisiae. Min-Seok, R., Kawamata, Y., Nakamura, H., Ohta, A., Takagi, M. J. Biochem. (1996) [Pubmed]
  32. Interaction of non-aggregated boar AWN-1 and AQN-3 with phospholipid matrices. A model for coating of spermadhesins to the sperm surface. Dostàlovà, Z., Calvete, J.J., Töpfer-Petersen, E. Biol. Chem. Hoppe-Seyler (1995) [Pubmed]
  33. Mutation of the htrB locus of Haemophilus influenzae nontypable strain 2019 is associated with modifications of lipid A and phosphorylation of the lipo-oligosaccharide. Lee, N.G., Sunshine, M.G., Engstrom, J.J., Gibson, B.W., Apicella, M.A. J. Biol. Chem. (1995) [Pubmed]
  34. The use of the chemical shift of the phosphomonoester P-31 magnetic resonance peak for the determination of intracellular pH in the brains of neonates. Corbett, R.J., Laptook, A.R., Nunnally, R.L. Neurology (1987) [Pubmed]
  35. Studies on the effects of lactate transport inhibition, pyruvate, glucose and glutamine on amino acid, lactate and glucose release from the ischemic rat cerebral cortex. Phillis, J.W., Ren, J., O'Regan, M.H. J. Neurochem. (2001) [Pubmed]
  36. P-31 nuclear magnetic resonance analysis of brain: II. Effects of oxygen deprivation on isolated perfused and nonperfused rat brain. Kopp, S.J., Krieglstein, J., Freidank, A., Rachman, A., Seibert, A., Cohen, M.M. J. Neurochem. (1984) [Pubmed]
  37. Minimal oligosaccharide structures required for induction of immune responses against meningococcal immunotype L1, L2, and L3,7,9 lipopolysaccharides determined by using synthetic oligosaccharide-protein conjugates. Verheul, A.F., Boons, G.J., Van der Marel, G.A., Van Boom, J.H., Jennings, H.J., Snippe, H., Verhoef, J., Hoogerhout, P., Poolman, J.T. Infect. Immun. (1991) [Pubmed]
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