Gene Review:
ADAM9 - ADAM metallopeptidase domain 9
Homo sapiens
Synonyms:
ADAM 9, CORD9, Cellular disintegrin-related protein, Disintegrin and metalloproteinase domain-containing protein 9, KIAA0021, ...
- The disintegrin-metalloproteinases ADAM9, ADAM12, and ADAM15 are upregulated in gastric cancer. Carl-McGrath, S., Lendeckel, U., Ebert, M., Roessner, A., Röcken, C. Int. J. Oncol. (2005)
- Oxidative Stress Induces ADAM9 Protein Expression in Human Prostate Cancer Cells. Sung, S.Y., Kubo, H., Shigemura, K., Arnold, R.S., Logani, S., Wang, R., Konaka, H., Nakagawa, M., Mousses, S., Amin, M., Anderson, C., Johnstone, P., Petros, J.A., Marshall, F.F., Zhau, H.E., Chung, L.W. Cancer Res. (2006)
- Overexpression of ADAM9 in non-small cell lung cancer correlates with brain metastasis. Shintani, Y., Higashiyama, S., Ohta, M., Hirabayashi, H., Yamamoto, S., Yoshimasu, T., Matsuda, H., Matsuura, N. Cancer Res. (2004)
- ADAM9 expression is a significant and independent prognostic marker of PSA relapse in prostate cancer. Fritzsche, F.R., Jung, M., Tölle, A., Wild, P., Hartmann, A., Wassermann, K., Rabien, A., Lein, M., Dietel, M., Pilarsky, C., Calvano, D., Grützmann, R., Jung, K., Kristiansen, G. Eur. Urol. (2008)
- MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains. Weskamp, G., Krätzschmar, J., Reid, M.S., Blobel, C.P. J. Cell Biol. (1996)
- Mitogenic activity and signaling mechanism of 2-(14,15- epoxyeicosatrienoyl)glycerol, a novel cytochrome p450 arachidonate metabolite. Chen, J., Chen, J.K., Falck, J.R., Anjaiah, S., Capdevila, J.H., Harris, R.C. Mol. Cell. Biol. (2007)
- ADAM-9 (MDC-9/meltrin-gamma), a member of the a disintegrin and metalloproteinase family, regulates myeloma-cell-induced interleukin-6 production in osteoblasts by direct interaction with the alpha(v)beta5 integrin. Karadag, A., Zhou, M., Croucher, P.I. Blood (2006)
- How ADAM-9 and ADAM-11 differentially from estrogen receptor predict response to tamoxifen treatment in patients with recurrent breast cancer: a retrospective study. Sieuwerts, A.M., Meijer-van Gelder, M.E., Timmermans, M., Trapman, A.M., Garcia, R.R., Arnold, M., Goedheer, A.J., Portengen, H., Klijn, J.G., Foekens, J.A. Clin. Cancer Res. (2005)
- Adam-9 expression and regulation in human skin melanoma and melanoma cell lines. Zigrino, P., Mauch, C., Fox, J.W., Nischt, R. Int. J. Cancer (2005)
- The disintegrin ADAM9 indirectly contributes to the physiological processing of cellular prion by modulating ADAM10 activity. Cissé, M.A., Sunyach, C., Lefranc-Jullien, S., Postina, R., Vincent, B., Checler, F. J. Biol. Chem. (2005)
- Involvement of ADAM9 in multinucleated giant cell formation of blood monocytes. Namba, K., Nishio, M., Mori, K., Miyamoto, N., Tsurudome, M., Ito, M., Kawano, M., Uchida, A., Ito, Y. Cell. Immunol. (2001)
- ADAM12 in human liver cancers: TGF-beta-regulated expression in stellate cells is associated with matrix remodeling. Le Pabic, H., Bonnier, D., Wewer, U.M., Coutand, A., Musso, O., Baffet, G., Clément, B., Théret, N. Hepatology (2003)
- A secreted form of human ADAM9 has an alpha-secretase activity for APP. Hotoda, N., Koike, H., Sasagawa, N., Ishiura, S. Biochem. Biophys. Res. Commun. (2002)
- Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity. Roghani, M., Becherer, J.D., Moss, M.L., Atherton, R.E., Erdjument-Bromage, H., Arribas, J., Blackburn, R.K., Weskamp, G., Tempst, P., Blobel, C.P. J. Biol. Chem. (1999)
- The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins. Mahimkar, R.M., Visaya, O., Pollock, A.S., Lovett, D.H. Biochem. J. (2005)
- Overexpression of ADAM9 enhances growth factor-mediated recycling of E-cadherin in human colon cancer cell line HT29 cells. Hirao, T., Nanba, D., Tanaka, M., Ishiguro, H., Kinugasa, Y., Doki, Y., Yano, M., Matsuura, N., Monden, M., Higashiyama, S. Exp. Cell Res. (2006)
- Expression of ADAM-9 mRNA and protein in human breast cancer. O'Shea, C., McKie, N., Buggy, Y., Duggan, C., Hill, A.D., McDermott, E., O'Higgins, N., Duffy, M.J. Int. J. Cancer (2003)
- Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta. Nelson, K.K., Schlöndorff, J., Blobel, C.P. Biochem. J. (1999)
- The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs. Amour, A., Knight, C.G., English, W.R., Webster, A., Slocombe, P.M., Knäuper, V., Docherty, A.J., Becherer, J.D., Blobel, C.P., Murphy, G. FEBS Lett. (2002)