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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
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Disease relevance of Bronchopneumonia


Psychiatry related information on Bronchopneumonia


High impact information on Bronchopneumonia


Chemical compound and disease context of Bronchopneumonia


Biological context of Bronchopneumonia


Anatomical context of Bronchopneumonia

  • Therefore, production of DNT by B. bronchiseptica is necessary to produce the lesions of turbinate atrophy and bronchopneumonia in pigs infected with this organism [19].
  • NF-kappaB activity was induced in alveolar like cells by BALs in all groups, was higher in bronchopneumonia and infected ARDS groups (P<0.02), and was correlated to IL-1beta (P=0.0002), IL-8 (P=0.02), NTP (P=0.014), myeloperoxidase (P=0.016), and neutrophil counts (P=0.003) [20].
  • Bone marrow from a patient with bilateral staphylococcal bronchopneumonia who was treated with large doses of chloramphenicol was examined with the electron microscope [21].
  • In conclusion, cell-associated SP-D protein expression significantly decreases within hyperplastic epithelium of lungs from infected animals during chronic bronchopneumonia [22].
  • The combination of LPS and PmA induced a subacute bronchopneumonia characterised by macrophage, neutrophil, and lymphocyte infiltration, changes in Penh and an increase in the mRNA level of IFN-gamma while IL8, IL-18 and TNF-alpha mRNA levels remained unchanged [23].

Gene context of Bronchopneumonia

  • Areas with bronchopneumonia exhibited markedly decreased endothelial TM staining of alveolar walls and small vessels [24].
  • The peak of histopathological changes and inflammation in C57BL/6J mice was characterized by subacute lymphohistiocytic bronchopneumonia and persistent elevation of tumor necrosis factor alpha and macrophage inflammatory protein 2 in the lung but not in the serum [25].
  • In addition, cytokine production coincided with the onset of general and respiratory symptoms of influenza and with the development of a necrotizing bronchopneumonia [26].
  • The enzyme had the characteristics of a metalloprotease, a pH optimum of 6, and a temperature optimum of 45 degrees C. Intratracheal instillation of purified PSCP into rat lungs produced a bronchopneumonia characterized by polymorphonuclear cell infiltration and proteinaceous exudation into large airways [27].
  • As a result, bronchopneumonia, not PCP, is now the leading cause of death among the patients with AIDS in this study [28].

Analytical, diagnostic and therapeutic context of Bronchopneumonia


  1. Lung deposition and efficiency of nebulized amikacin during Escherichia coli pneumonia in ventilated piglets. Goldstein, I., Wallet, F., Nicolas-Robin, A., Ferrari, F., Marquette, C.H., Rouby, J.J. Am. J. Respir. Crit. Care Med. (2002) [Pubmed]
  2. Immunomodulatory and protective effects of moxifloxacin against Candida albicans-induced bronchopneumonia in mice injected with cyclophosphamide. Shalit, I., Horev-Azaria, L., Fabian, I., Blau, H., Kariv, N., Shechtman, I., Alteraz, H., Kletter, Y. Antimicrob. Agents Chemother. (2002) [Pubmed]
  3. Intravenous versus nebulized ceftazidime in ventilated piglets with and without experimental bronchopneumonia: comparative effects of helium and nitrogen. Tonnellier, M., Ferrari, F., Goldstein, I., Sartorius, A., Marquette, C.H., Rouby, J.J. Anesthesiology (2005) [Pubmed]
  4. Efficacy of different dosing schedules of tobramycin for treating a murine Klebsiella pneumoniae bronchopneumonia. Pechère, M., Letarte, R., Pechère, J.C. J. Antimicrob. Chemother. (1987) [Pubmed]
  5. Fatal pulmonary hypertension in identical twins with systemic lupus erythematosus. Wilson, L., Tomita, T., Braniecki, M. Hum. Pathol. (1991) [Pubmed]
  6. Callosal defect, microcephaly, severe mental retardation, and other anomalies in three sibs. da-Silva, E.O. Am. J. Med. Genet. (1988) [Pubmed]
  7. Population pharmacokinetics of moxifloxacin in plasma and bronchial secretions in patients with severe bronchopneumonia. Simon, N., Sampol, E., Albanese, J., Martin, C., Arvis, P., Urien, S., Lacarelle, B., Bruguerolle, B. Clin. Pharmacol. Ther. (2003) [Pubmed]
  8. Population pharmacokinetics of ceftriaxone and pharmacodynamic considerations in haemodialysed patients. Simon, N., Dussol, B., Sampol, E., Purgus, R., Brunet, P., Lacarelle, B., Berland, Y., Bruguerolle, B., Urien, S. Clinical pharmacokinetics. (2006) [Pubmed]
  9. Correlation between Torque tenovirus infection and serum levels of eosinophil cationic protein in children hospitalized for acute respiratory diseases. Maggi, F., Pifferi, M., Tempestini, E., Lanini, L., De Marco, E., Fornai, C., Andreoli, E., Presciuttini, S., Vatteroni, M.L., Pistello, M., Ragazzo, V., Macchia, P., Pietrobelli, A., Boner, A., Bendinelli, M. J. Infect. Dis. (2004) [Pubmed]
  10. Pneumococcal behavior and host responses during bronchopneumonia are affected differently by the cytolytic and complement-activating activities of pneumolysin. Jounblat, R., Kadioglu, A., Mitchell, T.J., Andrew, P.W. Infect. Immun. (2003) [Pubmed]
  11. Cefpodoxime proxetil. A review of its antibacterial activity, pharmacokinetic properties and therapeutic potential. Frampton, J.E., Brogden, R.N., Langtry, H.D., Buckley, M.M. Drugs (1992) [Pubmed]
  12. Penetration of ciprofloxacin into bronchial secretions from mechanically ventilated patients with nosocomial bronchopneumonia. Saux, P., Martin, C., Mallet, M.N., Papazian, L., Bruguerolle, B., De Micco, P., Gouin, F. Antimicrob. Agents Chemother. (1994) [Pubmed]
  13. Increased alpha-hydroxybutyrate dehydrogenase in serum from children with measles. Kano, K., Ichimura, T. Clin. Chem. (1992) [Pubmed]
  14. Cefepime versus cefotaxime in the treatment of lower respiratory tract infections. Barckow, D., Schwigon, C.D. J. Antimicrob. Chemother. (1993) [Pubmed]
  15. Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice. Miyazaki, S., Fujikawa, T., Matsumoto, T., Tateda, K., Yamaguchi, K. J. Antimicrob. Chemother. (2001) [Pubmed]
  16. Human pharmacokinetics and distribution in various tissues of ceftriaxone. Fraschini, F., Braga, P.C., Scarpazza, G., Scaglione, F., Pignataro, O., Sambataro, G., Mariani, C., Roviaro, G.C., Varoli, F., Esposti, G. Chemotherapy. (1986) [Pubmed]
  17. Effect of steroidal and non-steroidal anti-inflammatory drugs in combination with long-acting oxytetracycline on non-specific immunity of calves suffering from enzootic bronchopneumonia. Bednarek, D., Zdzisińska, B., Kondracki, M., Kandefer-Szerszeń, M. Vet. Microbiol. (2003) [Pubmed]
  18. Phagocytosis and oxidative burst of blood phagocytes in chronic obstructive airway disease. Müns, G., Rubinstein, I., Bergmann, K.C. Scand. J. Infect. Dis. (1995) [Pubmed]
  19. Role of the dermonecrotic toxin of Bordetella bronchiseptica in the pathogenesis of respiratory disease in swine. Brockmeier, S.L., Register, K.B., Magyar, T., Lax, A.J., Pullinger, G.D., Kunkle, R.A. Infect. Immun. (2002) [Pubmed]
  20. Bronchoalveolar lavage fluids of ventilated patients with acute lung injury activate NF-kappaB in alveolar epithelial cell line: role of reactive oxygen/nitrogen species and cytokines. Nys, M., Deby-Dupont, G., Habraken, Y., Legrand-Poels, S., Kohnen, S., Ledoux, D., Canivet, J.L., Damas, P., Lamy, M. Nitric Oxide (2003) [Pubmed]
  21. Chloramphenicol-induced mitochondrial and ultrastructural changes in hemopoietic cells. Skinnider, L.F., Ghadially, F.N. Arch. Pathol. Lab. Med. (1976) [Pubmed]
  22. Surfactant protein D expression in normal and pneumonic ovine lung. Grubor, B., Gallup, J.M., Ramírez-Romero, R., Bailey, T.B., Crouch, E.C., Brogden, K.A., Ackermann, M.R. Vet. Immunol. Immunopathol. (2004) [Pubmed]
  23. Pathophysiological changes occurring during Escherichia coli endotoxin and Pasteurella multocida challenge in piglets: relationship with cough and temperature and predicitive value for intensity of lesions. Halloy, D.J., Bouhet, S., Oswald, I.P., Goret-Nicaise, M., Kobisch, M., Mainil, J., Gustin, P.G. Vet. Res. (2004) [Pubmed]
  24. Association between decreased pulmonary endothelial cell thrombomodulin and local fibrin deposition in pneumonia. Albertson, C.M., Richter, K.K., Kudryk, B.J., Fink, L.M., Hauer-Jensen, M. Blood Coagul. Fibrinolysis (2001) [Pubmed]
  25. Microbial pathogenesis in cystic fibrosis: pulmonary clearance of mucoid Pseudomonas aeruginosa and inflammation in a mouse model of repeated respiratory challenge. Yu, H., Hanes, M., Chrisp, C.E., Boucher, J.C., Deretic, V. Infect. Immun. (1998) [Pubmed]
  26. Bronchoalveolar interferon-alpha, tumor necrosis factor-alpha, interleukin-1, and inflammation during acute influenza in pigs: a possible model for humans? Van Reeth, K., Nauwynck, H., Pensaert, M. J. Infect. Dis. (1998) [Pubmed]
  27. Purification and characterization of an extracellular protease from Pseudomonas cepacia. McKevitt, A.I., Bajaksouzian, S., Klinger, J.D., Woods, D.E. Infect. Immun. (1989) [Pubmed]
  28. Comparison of changing autopsy trends in the Bronx population with acquired immunodeficiency syndrome. Concepcion, L., Markowitz, G.S., Borczuk, A.C., Factor, S.M. Mod. Pathol. (1996) [Pubmed]
  29. Loracarbef (LY163892) versus amoxicillin/clavulanate in bronchopneumonia and lobar pneumonia. Hyslop, D.L., Jacobson, K., Guerra, F.J. Clinical therapeutics. (1992) [Pubmed]
  30. Intramural squamous cell carcinoma of the esophagus. McGregor, D.H., Mills, G., Boudet, R.A. Cancer (1976) [Pubmed]
  31. Fatal toxic epidermal necrolysis in autoimmune polyglandular syndrome type I. Porzionato, A., Zancaner, S., Betterle, C., Ferrara, S.D. J. Endocrinol. Invest. (2004) [Pubmed]
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