Disease relevance of Frontal Bone

• Thallium-201 uptake in eosinophilic granuloma of the frontal bone: comparison with technetium-99m-MDP imaging [1].
• MR imaging showed a mass in the right frontal bone with intra- and extracranial extension and a dural tail sign after gadopentetate dimeglumine administration, mimicking a meningioma in which the dural tail sign was due to a direct noninvasive superficial growth of the lesion [2].
• Cholesterol granuloma of the frontal bone: CT diagnosis [3].
• The presence of an extra-osseous lipoma on the forehead and of a vertical bony bar in the intracranial midline in contact with the frontal bone are definite signs of the presence of a lipoma in the corpus callosum [4].
• Osteoblasts derived from sagittal sutures with premature synostosis, noninvolved coronal sutures, and normal frontal bone were harvested and cultured as cells in an attempt to determine if osteoblasts at the site of premature fusion exhibited altered in vitro cellular dynamics [5].

High impact information on Frontal Bone

• However, this requirement is restricted to the developing calvarial aspect of the frontal bone, whereas the orbital aspect forms despite the ablation of Tgfbr2 gene, implying a differential requirement for TGFbeta signaling during the development of various regions of the frontal bone [6].
• Both the quantity and proliferation of the frontal bone skeletogenic mesenchyme are reduced in Msx2-Twist double mutants compared with individual mutants [7].
• In contrast, no significant difference was found in extent of lysine hydroxylation of the collagens of frontal bones of embryos and postnatal animals [8].
• Exposure of embryos to retinoic acid at E10.0 reduces this meningeal neural crest and inhibits parietal ossification, suggesting that intramembranous ossification of this mesodermal bone requires interaction with neural crest-derived meninges, whereas ossification of the neural crest-derived frontal bone is autonomous [9].
• Pedicles and antlers originate from a specialized region of the frontal bone; the 'antlerogeneic periosteum' and the systemic cue which triggers their development in the fawn is an increase in circulating androgen [10].

Chemical compound and disease context of Frontal Bone

• Treatment of some sinus diseases can be enhanced by access through direct sinus endoscopy for focal lesions, use of large frontal bone flaps for diffuse sinus lesions, standing surgery through a frontal flap for a variety of sinus disorders, and intralesional formalin for progressive ethmoidal hematomas [11].

Biological context of Frontal Bone

• As the OIFs of the parietal and frontal bones approach, but prior to any physical overlap, they lie in different planes dorsoventrally; the parietal OIF located dorsal to the frontal OIF, a pattern maintained throughout subsequent sutural morphogenesis [12].

Anatomical context of Frontal Bone

• In animals treated with TGF beta alone or TGF beta and indomethacin, then killed on day 19 (day 1 = day of first TGF beta injection), the combined frontal and parietal bones were heavier and the frontal bones were thicker than in controls [13].
• Since then, similar frontal burr holes have been made in five juvenile cases of moyamoya disease; this procedure involved making a burr hole in both frontal bones and incising both the dura and the arachnoid membrane [14].
• At 3 weeks of age, six Landrace White cross male pigs had a 3.75 x 3.0 mm titanium fixture (Noblepharma) inserted into their right frontal bone where the right frontal sinus would subsequently develop [15].
• Displacement of the mandible and the maxilla with growth in relationship to the frontal bone was recorded in eleven children with hemifacial microsomia, aged 3 to 14 years at the initial examination [16].

Associations of Frontal Bone with chemical compounds

• In frontal bone and cartilage, [3H] hydroxyproline content was decreased 88% and 57%, respectively, and [3H]proline content was decreased 68% and 37%, respectively; neither was affected in the aorta [17].
• Amalgam markers were placed in the parietal and frontal bones across the coronal suture, and were measured immediately after surgery and at the time of sacrifice to confirm mechanical immobility [18].
• CLINICAL PRESENTATION: Hydroxyapatite cement was used for reconstruction of a frontal bone defect secondary to a traumatic depressed cranial fracture in a 9-year-old male patient [19].
• Two radiopaque implants were inserted into each (left and right) frontal bone in five female rabbits [20].
• Twenty-eight tricalcium phosphate implants (15 mm diameter x 5 mm; pore size, 100-200 microns) were divided into experimental and control groups and placed on the frontal bone of 14 adult New Zealand White rabbits [21].

Gene context of Frontal Bone

• Here, we show that TGFbeta IIR is required for proliferation of osteoprogenitor cells in the CNC-derived frontal bone anlagen [6].
• He also has a defect of the anterior midline scalp with involvement of the frontal bone as documented by a computed tomography (CT) scan [22].
• The clinical diagnosis of HCC was made because of the presence of a liver mass on abdominal computed tomography (CT) scan, high serum alpha-fetoprotein value and tissue diagnosis on frontal bone biopsy [23].
• The olfactory aspect of the frontal bone bulged slightly outwards, medial walls of orbits were laterally displaced, parietal and interparietal showed distention and their related sagittal and coronal sutures unfused and open to 1 mm in places [24].

Analytical, diagnostic and therapeutic context of Frontal Bone

• Use of a rivet-like titanium clamp closure system to replace an external frontal bone flap after transfrontal craniotomy in a dog [25].
• Prenatal diagnosis of de novo interstitial 16q deletion in a fetus associated with sonographic findings of prominent coronal sutures, a prominent frontal bone, and shortening of the long bones [26].
• This case of a 65-year-old Korean man with HCC and metastatic frontal bone mass that regressed after radiotherapy for frontal bone mass without any other therapeutic modalities is described [23].
• MATERIALS AND METHODS: Under general endotracheal anesthesia, two Champy miniplates (titanium or stainless steel) were placed on the frontal bone in an animal model [27].
• By means of Vitallium screws and a small head cap of plaster of Paris it is possible to achieve stiff, external immobilization of facial fractures, even when they are situated in the frontal bones [28].

References