Disease relevance of Intraoperative Complications

• Keloids are skin fibrotic conditions characterized by an excess accumulation of extracellular matrix (ECM) components secondary to trauma or surgical injuries [1].
• Potential risk factors for endophthalmitis may include intraoperative complications, relative immune compromise, application of lidocaine 2% gel before povidone-iodine preparation, and inferior incision location [2].
• Pseudo vitreous hemorrhage: a new intraoperative complication of sodium hyaluronate [3].
• Thus, in our experimental conditions, propranolol treatment: does not modify fetal weight; has no effect on AIB placental transfer and tissue uptake, and could protect towards the stress of anesthesia and surgical injuries, since H2O transfer was impaired in control but not in treated animals [4].
• Both groups were comparable with regard to operative time (P = 0.77), intraoperative complications (P = 0.1), postoperative complications (P = 0.55), hospital stay (P = 0.13), convalescence (P = 0.96), and postoperative serum creatinine (112.2 vs 123.7 micromol/L [1.27 vs 1.4 mg/dL]; P = 0.31) [5].

High impact information on Intraoperative Complications

• Distinct temporal patterns of macrophage-inflammatory protein-2 and KC chemokine gene expression in surgical injury [6].
• We propose that deficiency of hypothalamic messengers after surgical injury induces a paracrine/autocrine effect of enhanced glucocorticoid activity due to up-regulated 11 beta-HSD1 activity [7].
• Neutrophil chemoattractant genes KC and MIP-2 are expressed in different cell populations at sites of surgical injury [8].
• RESULTS: Twenty-eight patients (2.5%) had intraoperative complications related to the vena cava preservation technique, which were treated during the operation [9].
• Of the LRP and RAP patients 21 (5.9%) and 3 (0.3%), respectively, experienced intraoperative complications [10].

Chemical compound and disease context of Intraoperative Complications

• BACKGROUND: The aim of this study was to determine whether halothane and isoflurane used during and after surgical injury attenuate subsequent hyperexcitability of spinal dorsal horn (SDH) neurons by preventing development of central sensitization [11].
• The effects of starvation and surgical injury on the plasma levels of glucose, free fatty acids, and neutral lipids in newborn babies suffering from various congenital anomalies [12].
• Twelve-lead electrocardiograms were performed daily and echocardiographic studies were performed on patients with either; electrocardiographic changes signifying likely myocardial damage, intraoperative complications, or elevated creatine kinase subfraction MB or troponin values [13].
• In the Control group, the rate of conversion was 16.3% (P<0.05) and the rate of intraoperative complications was 7.0% [14].
• The late recovery after isoflurane was equal to that obtained using an intravenous technique with alfentanil, although the peroperative complication rate was higher [15].

Biological context of Intraoperative Complications

• Kupffer cell complement receptor clearance function after surgical injury and phagocytosis of immune complexes: effect of changes in plasma fibronectin [16].

Anatomical context of Intraoperative Complications

• The ventricular septal defect may be close to or related to the membranous septum, and the atrioventricular bundle and the beginning of the bundle branches may be vulnerable to surgical injury [17].
• We examined whether the same response occurred after surgical injury, and whether this reduced activity was associated with differential monocyte toll-like receptor (TLR) expression [18].
• These data suggest that the increase in incorporation of glucosamine and proline into connective tissue protein by postsurgical repair cells may be directly modulated by macrophages recruited in response to surgical injury and that this increase is due to the fibroproliferative effect of postsurgical macrophages [19].
• Extracellular matrices in peritendinous connective tissue after surgical injury to the chicken flexor tendon [20].
• The effect of occlusal alteration upon healing of the periodontium after surgical injury was studied in 62 male Wistar rats, nine weeks of age [21].

Gene context of Intraoperative Complications

• KC and macrophage-inflammatory protein-2 (MIP-2) are CXC chemokines that exhibit distinct temporal patterns of expression in the skin following surgical injury [8].
• Conclusions: PBMCs from septic patients, but not following surgical injury, have a reduced capacity to respond to a secondary inflammatory signal, but this defect is not associated with reduced TLR-4 or CD14 expression [18].
• CONCLUSIONS: Cytokine response after cholecystectomy demonstrates the lesser degree of surgical injury in the laparoscopic group, however, TNF-alpha demonstrates on day 4 a similar increase in both groups [22].
• Similarly, the microglial and astroglial responses to surgical injury of the cortex are significantly slower in LIF KO mice compared with WT mice [23].
• MATERIALS AND METHODS: Fifty-four adult male CD rats were divided into three groups: 1) saline-injected (0.1 ml.) into the tunica albuginea; 2) TGF-beta1 (0.5 microgram.) injected into the tunica albuginea; and 3) surgical injury to the tunica albuginea [24].

Analytical, diagnostic and therapeutic context of Intraoperative Complications

• This diagnostic procedure avoids the upper midline incision and the surgical injury of cholecystectomy [25].
• Thus, surgical injury hastens regression of sensory analgesia during continuous epidural bupivacaine infusion [26].
• Among other questions the participants were asked for the number of lasersurgical treatments of the larynx performed in the past, the usual type of ETTs in use, whether other safety precautions were taken during CO2 laser surgery of the larynx and for intraoperative complications like tube ignition, fires or combustions [27].
• Effects of the administration of progesterone and adrenal medullectomy on the plasma fibrinogen levels in rats with surgical injury (laparotomy) [28].
• End points were intraoperative complications and patency of the gastro jejunostomy [29].

References