Chemical Compound Review:
CCRIS 3974 zinc 2-[(3-azanidyl-1-oxido...
Synonyms:
LS-162824, NCGC00181764-01, Polaprezinc [INN], Promac (antiulcer agent)
This record was replaced with 9369.
- Insulin-like growth factor I plays a role in gastric wound healing: evidence using a zinc derivative, polaprezinc, and an in vitro rabbit wound repair model. Watanabe, S., Wang, X.E., Hirose, M., Kivilioto, T., Osada, T., Miwa, H., Oide, H., Kitamura, T., Yoneta, T., Seto, K., Sato, N. Aliment. Pharmacol. Ther. (1998)
- Polaprezinc attenuates the Helicobacter pylori-induced gastric mucosal leucocyte activation in Mongolian gerbils--a study using intravital videomicroscopy. Suzuki, H., Mori, M., Seto, K., Miyazawa, M., Kai, A., Suematsu, M., Yoneta, T., Miura, S., Ishii, H. Aliment. Pharmacol. Ther. (2001)
- Polaprezinc attenuates Helicobacter pylori-associated gastritis in Mongolian gerbils. Ishihara, R., Iishi, H., Sakai, N., Yano, H., Uedo, N., Narahara, H., Iseki, K., Mikuni, T., Ishiguro, S., Tatsuta, M. Helicobacter (2002)
- Evaluation of topical external medicine for 5-fluorouracil-induced oral mucositis in hamsters. Mitsuhashi, H., Suemaru, K., Li, B., Cui, R., Araki, H. Eur. J. Pharmacol. (2006)
- Role of elastase and active oxygen species in gastric mucosal injury induced by aspirin administration in Helicobacter pylori-infected Mongolian gerbils. Yoshida, N., Sugimoto, N., Ochiai, J., Nakamura, Y., Ichikawa, H., Naito, Y., Yoshikawa, T. Aliment. Pharmacol. Ther. (2002)
- Polaprezinc down-regulates proinflammatory cytokine-induced nuclear factor-kappaB activiation and interleukin-8 expression in gastric epithelial cells. Shimada, T., Watanabe, N., Ohtsuka, Y., Endoh, M., Kojima, K., Hiraishi, H., Terano, A. J. Pharmacol. Exp. Ther. (1999)
- Effect of polaprezinc (N-(3-aminopropionyl)-L-histidinato zinc), a novel antiulcer agent containing zinc, on cellular proliferation: role of insulin-like growth factor I. Seto, K., Yoneta, T., Suda, H., Tamaki, H. Biochem. Pharmacol. (1999)
- Mucosal ulcerogenic action of monochloramine in rat stomachs: effects of polaprezinc and sucralfate. Kato, S., Nishiwaki, H., Konaka, A., Takeuchi, K. Dig. Dis. Sci. (1997)
- Polaprezinc (N-(3-aminopropionyl)-L-histidinato zinc) ameliorates dextran sulfate sodium-induced colitis in mice. Ohkawara, T., Takeda, H., Kato, K., Miyashita, K., Kato, M., Iwanaga, T., Asaka, M. Scand. J. Gastroenterol. (2005)
- Ulcerogenic and healing impairing actions of monochloramine in rat stomachs: effects of zinc L-carnosine, polaprezinc. Nishiwaki, H., Kato, S., Sugamoto, S., Umeda, M., Morita, H., Yoneta, T., Takeuchi, K. J. Physiol. Pharmacol. (1999)
- Tissue distribution of polaprezinc in rats determined by the double tracer method. Furuta, S., Suzuki, M., Toyama, S., Miwa, M., Sano, H. Journal of pharmaceutical and biomedical analysis. (1999)
- Polaprezinc, a gastroprotective agent: attenuation of monochloramine-evoked gastric DNA fragmentation. Suzuki, H., Mori, M., Seto, K., Nagahashi, S., Kawaguchi, C., Morita, H., Suzuki, M., Miura, S., Yoneta, T., Ishii, H. J. Gastroenterol. (1999)
- Polaprezinc protects gastric mucosal cells from noxious agents through antioxidant properties in vitro. Hiraishi, H., Sasai, T., Oinuma, T., Shimada, T., Sugaya, H., Terano, A. Aliment. Pharmacol. Ther. (1999)
- Disposition of polaprezinc (zinc L-carnosine complex) in rat gastrointestinal tract and effect of cimetidine on its adhesion to gastric tissues. Furuta, S., Toyama, S., Miwa, M., Sano, H. J. Pharm. Pharmacol. (1995)
- Polaprezinc protects human colon cells from oxidative injury induced by hydrogen peroxide: Relevant to cytoprotective heat shock proteins. Ohkawara, T., Nishihira, J., Nagashima, R., Takeda, H., Asaka, M. World J. Gastroenterol. (2006)
- Polaprezinc, a mucosal protective agent, in combination with lansoprazole, amoxycillin and clarithromycin increases the cure rate of Helicobacter pylori infection. Kashimura, H., Suzuki, K., Hassan, M., Ikezawa, K., Sawahata, T., Watanabe, T., Nakahara, A., Mutoh, H., Tanaka, N. Aliment. Pharmacol. Ther. (1999)