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Chemical Compound Review

PCMBS     chloro-(4-sulfophenyl)mercury

Synonyms: C6H4ClHgO3S, CHEBI:33206, AC1L1WOV, LS-175626, AI3-51823, ...
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Disease relevance of Chloromercuriphenylsulfonate


Psychiatry related information on Chloromercuriphenylsulfonate


High impact information on Chloromercuriphenylsulfonate


Chemical compound and disease context of Chloromercuriphenylsulfonate


Biological context of Chloromercuriphenylsulfonate


Anatomical context of Chloromercuriphenylsulfonate


Associations of Chloromercuriphenylsulfonate with other chemical compounds

  • Glucose transport activity was stereospecific, temperature-dependent, sensitive to inactivation by p-chloromercuriphenylsulfonate, and accompanied plasma membrane material during subcellular fractionation [23].
  • Growth for 96 hours in the presence of both EGF and cholera toxin or another cyclic AMP elevating agent induced an ectoATPase activity which was more active with CaATP and resistant to inhibition by the sulfydryl reagent, p-chloromercuriphenylsulfonate (pCMPS) (Knowles: Arch. Biochem. Biophys., 263: 264-271, 1988) [24].
  • The sulfhydryl reagents mersalyl, PCMBS, NEM, and DTNB also inhibited net uptake, suggesting that sulfhydryl groups may be involved in the activity of the carrier protein [25].
  • Use of specific inhibitors, including L-trans-epoxysuccinyl-leucylamino-(4- guanidino)-butane (E-64), p-chloromercuriphenylsulfonic acid (PCMS), and oryzacystatin, indicated that nearly all of the proteinase activity against casein was contributed by cysteine proteinases [26].
  • D-Aspartate, p-chloromercuriphenylsulfonate and GABA had comparable effects on isolated medial giant nerve fibers.These studies indicate that L-glutamate is taken up primarily by the periaxonal glia of crayfish central nerve fibers by a low-affinity, saturable, Na(+)-dependent transport system and is retained by the fibers primarily in that form [27].

Gene context of Chloromercuriphenylsulfonate


Analytical, diagnostic and therapeutic context of Chloromercuriphenylsulfonate


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