The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

CMTD     2-tetradecylsulfanylethanoic acid

Synonyms: Lopac-T-1698, CHEMBL187734, T1698_SIGMA, CCG-205229, KST-1A3586, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Lopac-T-1698


High impact information on Lopac-T-1698


Chemical compound and disease context of Lopac-T-1698


Biological context of Lopac-T-1698


Anatomical context of Lopac-T-1698


Associations of Lopac-T-1698 with other chemical compounds


Gene context of Lopac-T-1698


Analytical, diagnostic and therapeutic context of Lopac-T-1698


  1. Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha. Tobin, K.A., Steineger, H.H., Alberti, S., Spydevold, O., Auwerx, J., Gustafsson, J.A., Nebb, H.I. Mol. Endocrinol. (2000) [Pubmed]
  2. A bioactively modified fatty acid improves survival and impairs metastasis in preclinical models of acute leukemia. Iversen, P.O., Sørensen, D.R., Tronstad, K.J., Gudbrandsen, O.A., Rustan, A.C., Berge, R.K., Drevon, C.A. Clin. Cancer Res. (2006) [Pubmed]
  3. Metabolic effects of thia fatty acids. Berge, R.K., Skorve, J., Tronstad, K.J., Berge, K., Gudbrandsen, O.A., Grav, H. Curr. Opin. Lipidol. (2002) [Pubmed]
  4. Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter. Schoonjans, K., Watanabe, M., Suzuki, H., Mahfoudi, A., Krey, G., Wahli, W., Grimaldi, P., Staels, B., Yamamoto, T., Auwerx, J. J. Biol. Chem. (1995) [Pubmed]
  5. Mitochondrial-targeted fatty acid analog induces apoptosis with selective loss of mitochondrial glutathione in promyelocytic leukemia cells. Tronstad, K.J., Gjertsen, B.T., Krakstad, C., Berge, K., Brustugun, O.T., Døskeland, S.O., Berge, R.K. Chem. Biol. (2003) [Pubmed]
  6. Tetradecylthioacetic acid and tetradecylselenoacetic acid inhibit lipid peroxidation and interact with superoxide radical. Muna, Z.A., Bolann, B.J., Chen, X., Songstad, J., Berge, R.K. Free Radic. Biol. Med. (2000) [Pubmed]
  7. Hormonal and substrate regulation of 3-thia fatty acid metabolism in Morris 7800 C1 hepatoma cells. Hvattum, E., Grav, H.J., Bremer, J. Biochem. J. (1993) [Pubmed]
  8. Retinoid X receptor (RXR alpha) gene expression is regulated by fatty acids and dexamethasone in hepatic cells. Steineger, H.H., Arntsen, B.M., Spydevold, O., Sørensen, H.N. Biochimie (1997) [Pubmed]
  9. Optimization of methods and treatment conditions for studying effects of fatty acids on cell growth. Tronstad, K.J., Berge, K., Flindt, E.N., Kristiansen, K., Berge, R.K. Lipids (2001) [Pubmed]
  10. Substrate and hormone regulation of palmitoyl-CoA synthetase in 7800 C1 Morris hepatoma cells and cultured rat hepatocytes. Wu, P., Skrede, S., Hvattum, E., Bremer, J. Biochim. Biophys. Acta (1993) [Pubmed]
  11. Effect of topical PPARbeta/delta and PPARgamma agonists on plaque psoriasis. A pilot study. Kuenzli, S., Saurat, J.H. Dermatology (Basel) (2003) [Pubmed]
  12. 1-(Carboxymethylthio)tetradecane attenuates PDGF- and TPA-induced c-fos mRNA expression and increases the formation of phosphatidylethanolamine with a shift from less to more polar molecular species in C3H/10T1/2 cells. Helleland, C., Eiane, S.A., Berge, R.K., Holmsen, H., Lillehaug, J.R. Exp. Cell Res. (1997) [Pubmed]
  13. Modulation of rat liver apolipoprotein gene expression and serum lipid levels by tetradecylthioacetic acid (TTA) via PPARalpha activation. Raspé, E., Madsen, L., Lefebvre, A.M., Leitersdorf, I., Gelman, L., Peinado-Onsurbe, J., Dallongeville, J., Fruchart, J.C., Berge, R., Staels, B. J. Lipid Res. (1999) [Pubmed]
  14. Antiproliferative effects of a non-beta-oxidizable fatty acid, tetradecylthioacetic acid, in native human acute myelogenous leukemia blast cultures. Tronstad, K.J., Bruserud, Ø., Berge, K., Berge, R.K. Leukemia (2002) [Pubmed]
  15. Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance. Madsen, L., Guerre-Millo, M., Flindt, E.N., Berge, K., Tronstad, K.J., Bergene, E., Sebokova, E., Rustan, A.C., Jensen, J., Mandrup, S., Kristiansen, K., Klimes, I., Staels, B., Berge, R.K. J. Lipid Res. (2002) [Pubmed]
  16. Tetradecylthioacetic acid (a 3-thia fatty acid) decreases triacylglycerol secretion in CaCo-2 cells. Gedde-Dahl, A., Ranheim, T., Drevon, C.A., Skrede, S., Berge, R.K., Rustan, A.C. J. Lipid Res. (1995) [Pubmed]
  17. Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid. Westergaard, M., Henningsen, J., Svendsen, M.L., Johansen, C., Jensen, U.B., Schrøder, H.D., Kratchmarova, I., Berge, R.K., Iversen, L., Bolund, L., Kragballe, K., Kristiansen, K. J. Invest. Dermatol. (2001) [Pubmed]
  18. Tetradecylthioacetic acid reduces the amount of lipid droplets, induces megamitochondria formation and increases the fatty acid oxidation in rat heart. Hexeberg, S., Frøyland, L., Asiedu, D.K., Demoz, A., Berge, R.K. J. Mol. Cell. Cardiol. (1995) [Pubmed]
  19. Stimulation of fatty acid oxidation by a 3-thia fatty acid reduces triacylglycerol secretion in cultured rat hepatocytes. Skrede, S., Bremer, J., Berge, R.K., Rustan, A.C. J. Lipid Res. (1994) [Pubmed]
  20. Eicosapentaenoic acid and sulphur substituted fatty acid analogues inhibit the proliferation of human breast cancer cells in culture. Abdi-Dezfuli, F., Frøyland, L., Thorsen, T., Aakvaag, A., Berge, R.K. Breast Cancer Res. Treat. (1997) [Pubmed]
  21. Hepatic fatty acid metabolism as a determinant of plasma and liver triacylglycerol levels. Studies on tetradecylthioacetic and tetradecylthiopropionic acids. Asiedu, D.K., al-Shurbaji, A., Rustan, A.C., Björkhem, I., Berglund, L., Berge, R.K. Eur. J. Biochem. (1995) [Pubmed]
  22. Gas chromatographic measurement of 3- and 4-thia fatty acids incorporated into various classes of rat liver lipids during feeding experiments. Grav, H.J., Asiedu, D.K., Berge, R.K. J. Chromatogr. B, Biomed. Appl. (1994) [Pubmed]
  23. Evaluation of the therapeutic potential of PPARalpha agonists for X-linked adrenoleukodystrophy. Rampler, H., Weinhofer, I., Netik, A., Forss-Petter, S., Brown, P.J., Oplinger, J.A., Bugaut, M., Berger, J. Mol. Genet. Metab. (2003) [Pubmed]
  24. Antiinflammatory effects of tetradecylthioacetic acid involve both peroxisome proliferator-activated receptor alpha-dependent and -independent pathways. Dyrøy, E., Yndestad, A., Ueland, T., Halvorsen, B., Damås, J.K., Aukrust, P., Berge, R.K. Arterioscler. Thromb. Vasc. Biol. (2005) [Pubmed]
  25. The metabolic syndrome and the hepatic fatty acid drainage hypothesis. Berge, R.K., Tronstad, K.J., Berge, K., Rost, T.H., Wergedahl, H., Gudbrandsen, O.A., Skorve, J. Biochimie (2005) [Pubmed]
  26. Immunomodulating effects of 3-thia fatty acids in activated peripheral blood mononuclear cells. Aukrust, P., Wergedahl, H., Müller, F., Ueland, T., Dyrøy, E., Damås, J.K., Frøland, S.S., Berge, R.K. Eur. J. Clin. Invest. (2003) [Pubmed]
  27. Sustained retention of tetradecylthioacetic acid after local delivery reduces angioplasty-induced coronary stenosis in the minipig. Pettersen, R.J., Muna, Z.A., Kuiper, K.K., Svendsen, E., Müller, F., Aukrust, P., Berge, R.K., Nordrehaug, J.E. Cardiovasc. Res. (2001) [Pubmed]
  28. Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status. Tronstad, K.J., Berge, K., Dyroy, E., Madsen, L., Berge, R.K. Biochem. Pharmacol. (2001) [Pubmed]
  29. Tetradecylthioacetic acid reduces stenosis development after balloon angioplasty injury of rabbit iliac arteries. Kuiper, K.K., Muna, Z.A., Erga, K.S., Dyrøy, E., Svendsen, E., Berge, R.K., Nordrehaug, J.E. Atherosclerosis (2001) [Pubmed]
  30. Lipid-lowering and anti-inflammatory effects of tetradecylthioacetic acid in HIV-infected patients on highly active antiretroviral therapy. Fredriksen, J., Ueland, T., Dyrøy, E., Halvorsen, B., Melby, K., Melbye, L., Skalhegg, B.S., Bohov, P., Skorve, J., Berge, R.K., Aukrust, P., Frøland, S.S. Eur. J. Clin. Invest. (2004) [Pubmed]
WikiGenes - Universities